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Activation in these networks was also compared between the patient group and healthy controls (<jats:italic>n<\/jats:italic>\u00a0=\u00a020).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the patient group, higher levels of performance on measures of verbal memory and executive functioning were related to increased connectivity within the <jats:styled-content style=\"fixed-case\">DMN<\/jats:styled-content> (i.e., inferior parietal lobe; precuneus). Greater depression severity was related to reduced connectivity between the <jats:styled-content style=\"fixed-case\">SN<\/jats:styled-content> and a node of the <jats:styled-content style=\"fixed-case\">DMN<\/jats:styled-content> (i.e., posterior cingulate cortex) and higher depersonalization symptoms were related to enhanced connectivity between the <jats:styled-content style=\"fixed-case\">SN<\/jats:styled-content> and a node of the <jats:styled-content style=\"fixed-case\">DMN<\/jats:styled-content> (i.e., middle temporal gyrus). Higher symptoms of depersonalization were also associated with reduced integration of the <jats:styled-content style=\"fixed-case\">DMN<\/jats:styled-content> with the medial frontal gyrus. Relative to controls, patients with <jats:styled-content style=\"fixed-case\">MDD<\/jats:styled-content> showed greater connectivity of the ventromedial prefrontal cortex within the <jats:styled-content style=\"fixed-case\">DMN<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Intrinsic connectivity network patterns are related to cognitive performance and symptom presentation among trauma\u2010exposed patients with <jats:styled-content style=\"fixed-case\">MDD<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/brb3.664","type":"journal-article","created":{"date-parts":[[2017,4,3]],"date-time":"2017-04-03T22:31:48Z","timestamp":1491258708000},"source":"Crossref","is-referenced-by-count":19,"title":["Relation between patterns of intrinsic network connectivity, cognitive functioning, and symptom presentation in trauma\u2010exposed patients with major depressive disorder"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3639-1982","authenticated-orcid":false,"given":"Melissa","family":"Parlar","sequence":"first","affiliation":[{"name":"McMaster Integrative Neuroscience Discovery and Study McMaster University  Hamilton ON Canada"},{"name":"Mood Disorders Program St. Joseph's Healthcare  Hamilton ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Densmore","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Western Ontario  London ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey B.","family":"Hall","sequence":"additional","affiliation":[{"name":"Department of Psychology, Neuroscience, and Behaviour McMaster University  Hamilton ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul A.","family":"Frewen","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Western Ontario  London ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth A.","family":"Lanius","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Western Ontario  London ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret C.","family":"McKinnon","sequence":"additional","affiliation":[{"name":"McMaster Integrative Neuroscience Discovery and Study McMaster University  Hamilton ON Canada"},{"name":"Mood Disorders Program St. Joseph's Healthcare  Hamilton ON Canada"},{"name":"Homewood Research Institute  Guelph ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,31]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-012-0440-3"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2011.12.002"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2013.11.027"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2006.09.073"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0145-2134(02)00541-0"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jts.2490080106"},{"key":"e_1_2_7_8_1","first-page":"187","article-title":"Alterations in default network connectivity in posttraumatic stress disorder related to early\u2010life trauma","volume":"34","author":"Bluhm R. 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