{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T04:29:27Z","timestamp":1775017767285,"version":"3.50.1"},"reference-count":48,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T00:00:00Z","timestamp":1725494400000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      Recent advances in artificial intelligence (AI) have been substantial. We investigated the effectiveness of an online meeting in which normal older adults (\n                      <jats:italic>otokai<\/jats:italic>\n                      ) used a music\u2010generative AI that transforms text to music (Music Trinity Generative Algorithm\u2010Human Refined [MusicTGA\u2010HR]).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>One hundred eighteen community\u2010dwelling, cognitively normal older adults were recruited through the internet (64 men, 54 women; mean age: 69.4\u00a0\u00b1\u00a04.4 years). Using MusicTGA\u2010HR, the participants chose music that they thought was the most suitable to a given theme. We established 11 classes of 7\u201310 members and one instructor each. Each class held an online meeting once a week, and each participant presented the music they chose. The other participants and the instructor then commented on the music. Neuropsychological assessments were performed before and after the intervention for 6 months, and the results before and after the intervention were statistically analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The category and letter word fluencies (WFs) were significantly improved (category WF:\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a0.003; letter WF:\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a0.036), and the time of the Trail\u2010Making Test\u2010B was also significantly shortened (\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a0.039). The Brain Assessment, an online cognitive test we developed, showed significant improvement in the memory of numbers (\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      &lt;\u00a0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      The online meeting of the\n                      <jats:italic>otokai<\/jats:italic>\n                      , which used music\u2010generative AI, improved the frontal lobe function and memory of independent normal older adults.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.70007","type":"journal-article","created":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T13:43:57Z","timestamp":1725543837000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Transforming text to music using artificial intelligence improves the frontal lobe function of normal older adults"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7704-7232","authenticated-orcid":false,"given":"Masayuki","family":"Satoh","sequence":"first","affiliation":[{"name":"Department of Dementia and Neuropsychology, Advanced Institute of Industrial Technology Tokyo Metropolitan Public University Corporation  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Inoue","sequence":"additional","affiliation":[{"name":"Amadeus Code, Co., Ltd  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun\u2010ichi","family":"Ogawa","sequence":"additional","affiliation":[{"name":"Department of Music Research Yamaha Music Foundation  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken\u2010ichi","family":"Tabei","sequence":"additional","affiliation":[{"name":"School of Industrial Technology, Advanced Institute of Industrial Technology Tokyo Metropolitan Public University Corporation  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiaki","family":"Kamikawa","sequence":"additional","affiliation":[{"name":"Department of Dementia and Neuropsychology, Advanced Institute of Industrial Technology Tokyo Metropolitan Public University Corporation  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makiko","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Dementia and Neuropsychology, Advanced Institute of Industrial Technology Tokyo Metropolitan Public University Corporation  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayaka","family":"Yoshizawa","sequence":"additional","affiliation":[{"name":"Amadeus Code, Co., Ltd  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gyo","family":"Kitagawa","sequence":"additional","affiliation":[{"name":"Amadeus Code, Co., Ltd  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yosinori","family":"Ota","sequence":"additional","affiliation":[{"name":"Research Institute of Brain Activation  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,9,5]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"Annual Report on the Ageing Society. (2010). (2010\u20102011).Cabinet Office Government of Japan."},{"key":"e_1_2_10_3_1","unstructured":"Annual Report on the Ageing Society. (2021).Cabinet Office Government of Japan."},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474\u20104422(11)70072\u20102"},{"key":"e_1_2_10_5_1","unstructured":"Communication Usage Trend Survey. 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