{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:02:58Z","timestamp":1772118178504,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T00:00:00Z","timestamp":1733961600000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007219","name":"Natural Science Foundation of Shanghai Municipality","doi-asserted-by":"publisher","award":["20ZR1434700"],"award-info":[{"award-number":["20ZR1434700"]}],"id":[{"id":"10.13039\/100007219","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Micturition desire\u2010awakening (MDA) function plays a pivotal role in the development of primary nocturnal enuresis (PNE); however, its neural correlates remain largely unexplored. Consequently, this study aimed to identify specific brain regional activities associated with MDA function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Neuroimaging data were collected from 173 children with varying MDA functional grade scores at the Department of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center, from July 2018 to November 2022. Resting\u2010state images were analyzed using whole\u2010brain correlation techniques and AlphaSim correction to identify brain regional activities and resting\u2010state functional connectivity (RSFC) associated with MDA functional grade scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Whole\u2010brain correlation analysis demonstrated that the fractional amplitude of low\u2010frequency fluctuations in the right angular gyrus (AG) exhibited a negative correlation with MDA functional grade scores (\n                      <jats:italic>r<\/jats:italic>\n                      <jats:sub>s<\/jats:sub>\n                      = \u22120.336,\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001), indicating reduced neural activity in this region with MDA dysfunction. Conversely, RSFC between the right middle frontal gyrus and the right AG was positively correlated with MDA functional grade scores (\n                      <jats:italic>r<\/jats:italic>\n                      <jats:sub>s<\/jats:sub>\n                      = 0.274,\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001), suggesting increased connectivity in these areas\u00a0associated with worse MDA functionality.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These findings provide preliminary insights into the neural underpinnings of MDA functionality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.70177","type":"journal-article","created":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T02:39:48Z","timestamp":1734057588000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Resting\u2010State Activities of the Angular Gyrus and the Micturition Desire\u2010Awakening Function in Children With and Without Enuresis"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4149-3246","authenticated-orcid":false,"given":"Xindi","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center, School of Medicine Shanghai Jiao Tong University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaogen","family":"Zhong","sequence":"additional","affiliation":[{"name":"Department of Developmental and Behavioral Pediatrics, Shanghai Children's 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