{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T03:48:37Z","timestamp":1787888917488,"version":"build-2784847793"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,4,7]],"date-time":"2017-04-07T00:00:00Z","timestamp":1491523200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Project of the department of health and family planning bureau of Zhoushan City, Zhejiang Province, China","award":["2014A17"],"award-info":[{"award-number":["2014A17"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2017,5]]},"abstract":"Abstract<\/jats:title>Objective<\/jats:title>Patients with Parkinson's disease (PD<\/jats:styled-content>) may have sensory dysfunction, and it can be more easily demonstrated through electrophysiologic testing. We aimed to explore whether the impairment of brainstem visual and auditory passageway exists in PD<\/jats:styled-content> patients using visual evoked potential (VEP<\/jats:styled-content>) and brainstem auditory evoked potential (BAEP<\/jats:styled-content>) examinations.<\/jats:p><\/jats:sec>Methods<\/jats:title>Forty\u2010two PD<\/jats:styled-content> cases and thirty controls participated in the study.\u00a0All subjects underwent the VEP<\/jats:styled-content> and BAEP<\/jats:styled-content> examinations. The N75, P100, N145 latencies and P100 amplitude of VEP<\/jats:styled-content>, the latencies of waves I, III<\/jats:styled-content>, V and the interpeak latencies (IPL<\/jats:styled-content>) of waves I\u2013III<\/jats:styled-content>, III<\/jats:styled-content>\u2013V, I\u2013V were measured.<\/jats:p><\/jats:sec>Results<\/jats:title>The N75, P100, N145 latencies of VEP<\/jats:styled-content>, but not the amplitude of P100, were significantly longer in patients with PD than the control group (p\u00a0<\/jats:italic><\u00a0<\/jats:italic>.05). The latencies of wave III<\/jats:styled-content> and wave V, the IPL<\/jats:styled-content> of III<\/jats:styled-content>\u2013V and I\u2013V were all significantly increased compared with control subjects while no significant difference was noted in waves I and I\u2013III IPL<\/jats:styled-content>.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Our results found that brainstem visual and auditory passageway may be impaired in PD<\/jats:styled-content> patients.<\/jats:p><\/jats:sec>Significance<\/jats:title>VEP<\/jats:styled-content> and BAEP<\/jats:styled-content> can be served as sensitive measurements in helping prognosis and assessment the severity of the disease.<\/jats:p><\/jats:sec>","DOI":"10.1002\/brb3.703","type":"journal-article","created":{"date-parts":[[2017,4,7]],"date-time":"2017-04-07T12:18:48Z","timestamp":1491567528000},"source":"Crossref","is-referenced-by-count":31,"title":["Evoked potential changes in patients with Parkinson's disease"],"prefix":"10.1002","volume":"7","author":[{"given":"Chunyan","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Neurology Zhoushan Hospital Wenzhou Medical University Zhoushan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaping","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurology Zhoushan Hospital Wenzhou Medical University Zhoushan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiguo","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Neurology Zhoushan Hospital Wenzhou Medical University Zhoushan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binda","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurology Zhoushan Hospital Wenzhou Medical University Zhoushan 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