{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T11:48:34Z","timestamp":1791460114279,"version":"4.3.4"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T00:00:00Z","timestamp":1739923200000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background:<\/jats:title><jats:p>Venous sinus stenting (VSS) has emerged as a novel treatment option for idiopathic intracranial hypertension (IIH) with transverse sinus stenosis (TSS). However, the efficacy of stenting in atypical IIH patients (body mass index [BMI]\u00a0&lt;\u00a024\u00a0kg\/m<jats:sup>2<\/jats:sup>, \u2265\u00a050\u00a0years of age, or male) has not been fully investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>The data of IIH\u00a0+\u00a0TSS patients who experienced conventional medical treatment failure and received VSS treatment at Beijing Tiantan Hospital in China between May 2021 and December 2022 were retrospectively reviewed in a prospectively maintained database. Baseline characteristics and periprocedural features were collected, and follow\u2010up clinical outcomes (intracranial pressure [ICP], stent\u2010adjacent stenosis, and symptoms and ophthalmic improvements) were compared between typical and atypical patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Data were available for 24 IIH\u00a0+\u00a0VSS patients. The median age was 37\u00a0years, and 95.8% were female. There were 9\/24 atypical patients (37.5%). At baseline, atypical patients had milder visual field defects than typical patients did, as reflected by the mean deviation (MD) of the worse eye (median of \u22123.08 decibel (dB) vs. \u22127.63\u00a0dB, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.027). Periprocedurally, 1\u20132 carotid self\u2010expandable stents with 7\u20139\u00a0mm in length and 40\u201350\u00a0mm in diameter were deployed at the site of the TSS. The median follow\u2010up duration was 12\u00a0months (range 8\u201322\u00a0months). At the last visit of follow\u2010up, stenting intervention significantly decreased the ICP and grade of papilledema and improved the best corrected visual acuity in the worse eye and MD in the fellow eye in both typical and atypical patients. The clinical outcomes of typical and atypical IIH\u00a0+\u00a0TSS patients were not significantly different, except that the MD of the worse eye in the atypical group was greater than that in the typical group (\u22121.33\u00a0dB vs. \u22125.31\u00a0dB, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>This study indicates a considerable proportion of atypical IIH cases among IIH\u00a0+\u00a0TSS patients with conventional medical treatment failure. Moreover, VSS seems to be an effective and safe therapeutic modality for atypical IIH\u00a0+\u00a0TSS.<\/jats:p><\/jats:sec>","DOI":"10.1002\/brb3.70351","type":"journal-article","created":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T01:17:26Z","timestamp":1740014246000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Outcomes of Stenting in Atypical Idiopathic Intracranial Hypertension Patients With Transverse Sinus Stenosis"],"prefix":"10.1002","volume":"15","author":[{"given":"Shuang","family":"Song","sequence":"first","affiliation":[{"name":"Department of Interventional Neuroradiology, Beijing Tiantan Hospital Capital Medical University  Beijing China"},{"name":"Department of Neurology the Second Hospital of Hebei Medical University  Shijiazhuang Hebei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongao","family":"Guan","sequence":"additional","affiliation":[{"name":"Department 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