{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:44:30Z","timestamp":1790837070103,"version":"4.1.0"},"reference-count":67,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:00:00Z","timestamp":1741824000000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Schizophrenia is a complex disorder characterized by altered brain functional connectivity, detectable during both task and resting state conditions using different neuroimaging methods. To this day, electroencephalography (EEG) studies have reported inconsistent results, showing both hyper\u2010 and hypo\u2010connectivity with diverse topographical distributions. Interpretation of these findings is complicated by volume\u2010conduction effects, where local brain activity fluctuations project simultaneously to distant scalp regions (zero\u2010phase lag), inducing spurious inter\u2010electrode correlations.<\/jats:p>\n                  <jats:p>\n                    <jats:bold>Aim<\/jats:bold>\n                    : In the present study, we explored the network dynamics of schizophrenia using a novel functional connectivity metric\u2014corrected imaginary phase locking value (ciPLV)\u2014which is insensitive to changes in amplitude as well as interactions at zero\u2010phase lag. This method, which is less prone to volume conduction effects, provides a more reliable\u00a0estimate of sensor\u2010space functional network connectivity in schizophrenia.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods<\/jats:bold>\n                    : We employed a cross\u2010sectional design, utilizing resting state EEG recordings from two adult groups: individuals diagnosed with chronic schizophrenia (\n                    <jats:italic>n<\/jats:italic>\n                    = 30) and a control group of healthy participants (\n                    <jats:italic>n<\/jats:italic>\n                    = 30), all aged between 18 and 55 years old.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results<\/jats:bold>\n                    : Our observations revealed that schizophrenia is characterized by a prevalence of excess theta (4\u20138\u00a0Hz) power localized to centroparietal electrodes. This was accompanied by significant alterations in inter\u2010 and intra\u2010hemispheric functional network connectivity patterns, mainly between frontotemporal regions within the theta band and frontoparietal regions within beta\/gamma bands.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions<\/jats:bold>\n                    : Our findings suggest that patients with schizophrenia demonstrate long\u2010range electrophysiological connectivity abnormalities that are independent of spectral power (i.e., volume conduction). Overall, distinct hemispheric differences were present in frontotemporo\u2010parietal networks in theta and beta\/gamma bands. While preliminary, these alterations could be promising new candidate biomarkers of chronic schizophrenia.\n                  <\/jats:p>","DOI":"10.1002\/brb3.70370","type":"journal-article","created":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T08:16:58Z","timestamp":1741853818000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Functional Connectivity in Chronic Schizophrenia: An EEG Resting\u2010State Study with Corrected Imaginary Phase\u2010Locking"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5855-1372","authenticated-orcid":false,"given":"Christophe","family":"Domingos","sequence":"first","affiliation":[{"name":"Institute of Psychology Jagiellonian University Krakow Poland"},{"name":"Life Quality Research Centre (CIEQV) Sport Science School of Rio Maior Rio Maior Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wiktor","family":"Wi\u0119c\u0142awski","sequence":"additional","affiliation":[{"name":"Institute of Psychology Jagiellonian University Krakow Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Frycz","sequence":"additional","affiliation":[{"name":"Institute of Psychology Jagiellonian University Krakow Poland"},{"name":"Doctoral School in the Social Sciences Jagiellonian University Krakow Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maja","family":"Wojcik","sequence":"additional","affiliation":[{"name":"Institute of Psychology Jagiellonian University Krakow Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"J\u00e1ni","sequence":"additional","affiliation":[{"name":"Institute of Psychology Jagiellonian University Krakow Poland"},{"name":"Department of Psychiatry, Faculty of Medicine Masaryk University and University Hospital Brno Brno Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Dudzi\u0144ska","sequence":"additional","affiliation":[{"name":"Institute of Psychology Jagiellonian University Krakow Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Przemys\u0142aw","family":"Adamczyk","sequence":"additional","affiliation":[{"name":"Institute of Psychology Jagiellonian University Krakow Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Ros","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience University of Geneva Geneva Switzerland"},{"name":"Center for Biomedical Imaging (CIBM) Geneva\u2010Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,13]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2014.12.018"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbu121"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00406\u2010018\u20100889\u2010z"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnsys.2015.00175"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1109\/EMBC.2013.6610881"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fninf.2015.00016"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.163.3.418"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1088\/1741\u20102552\/aacfe4"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1099745"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2022.853994"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2006.05.033"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2023.12.017"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2019.116356"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2015.00234"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2004.10.009"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbt072"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2016.08.009"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3901"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2015.09.034"},{"issue":"2","key":"e_1_2_12_21_1","first-page":"89","article-title":"Schizophrenia: a Disconnection Syndrome?","volume":"3","author":"Friston K. J.","year":"1995","journal-title":"Clinical Neuroscience"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2010.11.015"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2011.06.029"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2014.2642"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2022.110541"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2013.09.009"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2011.06.003"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/pcn.12495"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbq059"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100447.2008.01227.x"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2009.02.006"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059\u2010019\u20101716\u20101"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.2307\/2529310"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2017.02.076"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/epirev\/mxn001"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2021.08.020"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dcn.2021.101036"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00325"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532\u20105415.2005.53221.x"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2018.00521"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2010.07.015"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2004.04.029"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2016.08.003"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2010.11.009"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/0013\u20104694(94)90112\u20100"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.3389\/neuro.11.010.2008"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.3758\/s13428\u2010018\u201001193\u2010y"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2010.11.004"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2019.05.026"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2013.12.017"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2013.07.009"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.4306\/pi.2011.8.4.288"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0006\u20103223(00)00907\u20100"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00851.2013"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.20346"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbn176"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2013.05.028"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006\u20103223(97)00428\u20109"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2774"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2012.09.004"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2006.03.021"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(09)60995\u20108"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbn021"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev\u2010clinpsy\u2010032511\u2010143049"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0920\u20109964(00)00128\u20106"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.281053"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbab110"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajp.2021.102550"}],"container-title":["Brain and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.70370","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T01:42:25Z","timestamp":1749433345000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/brb3.70370"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":67,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["10.1002\/brb3.70370"],"URL":"https:\/\/doi.org\/10.1002\/brb3.70370","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1002\/BRB3.70370\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.70370\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.70370\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.70370\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.70370\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.70370\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.70370\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.70370\/v1\/review2","asserted-by":"object"}]},"ISSN":["2162-3279","2162-3279"],"issn-type":[{"value":"2162-3279","type":"print"},{"value":"2162-3279","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"2024-06-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70370"}}