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The connectivity and microstructure of key brain white matter pathways, including fronto\u2013temporal trajectories, have been implicated in psychosis and psychosis\u2010risk. Although sex differences in PLE prevalence and characteristics have been reported, most neuroimaging studies of PLE have primarily included mixed\u2010sex, samples and little research has been carried out in females only. This study examines the associations between PLE and white matter characteristics in young to middle\u2010aged females.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed cross\u2010sectional diffusion magnetic resonance imaging (dMRI) and self\u2010reported data from 661 females aged 9\u201344 years using the 15\u2010item version of The Community Assessment of Psychic Experiences (CAPE) questionnaire. Associations between CAPE subscales and other psychopathology measures were tested. Using linked independent component analysis (LICA), we decomposed the voxel\u2010wise data from 24 dMRI metrics across five different diffusion models into 10 spatially independent components. We then examined the association between the LICA subject weights and age. Next, we tested for associations between the LICA subject weights and both CAPE total and subscales scores using Bayesian statistics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>PLE were broadly associated with various domains of psychopathology and psychosocial factors. Moderate evidence emerged for an association between PLE and an LICA component reflecting a broad and complex pattern of diffusivity in major pathways, including the inferior fronto\u2013 occipital fasciculus, anterior thalamic radiation, and forceps minor. The persecutory ideations subscale showed the strongest evidence of an effect.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>PLE in young females are associated with a distinct multimodal white matter pattern reflecting microstructural characteristics in key commissural, association, and thalamocortical pathways in young females. The findings support that LICA is a valuable tool for fusing and decomposing advanced dMRI metrics to delineate white matter patterns that show sensitivity to PLE and mental distress.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.70587","type":"journal-article","created":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T03:49:58Z","timestamp":1748576998000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Linking Psychotic\u2010Like Experiences and Brain White Matter Microstructure in Young Women"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4793-4428","authenticated-orcid":false,"given":"Rikka","family":"Kjelkenes","sequence":"first","affiliation":[{"name":"Department of Psychology University of Oslo  Oslo Norway"},{"name":"Center for Precision Psychiatry, Division of Mental Health and Addiction Oslo University Hospital  Oslo 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