{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:00:02Z","timestamp":1772118002776,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T00:00:00Z","timestamp":1750118400000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Eosinophilic esophagitis (EoE) is a chronic inflammatory esophageal disease associated with dysphagia, food impaction, feeding difficulties, vomiting, and failure to thrive in children. These symptoms result from dysregulated neural control and inflammation\u2010induced tissue remodeling and may extend beyond esophageal dysfunction to impact sensory processing. This study aimed to evaluate the sensory processing difficulties in children with EoE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective case\u2010control study included children with EoE and age\u2010matched healthy controls. Sociodemographic data and medical histories were collected. Sensory processing abilities were evaluated using the sensory profile, which evaluates sensory performance across multiple domains.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 69 children aged 3\u201310 years participated in the study, including 22 diagnosed with EoE and 47 healthy controls. No significant demographic differences were found between groups (\n                      <jats:italic>p<\/jats:italic>\n                      &gt; 0.05). Children with EoE exhibited significantly greater sensory processing difficulties in oral sensory processing, vestibular processing, and oral sensory sensitivity compared to healthy controls (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Sensory processing difficulties in children with EoE extend beyond feeding challenges, affecting oral sensory and vestibular processing functions. Incorporating sensory processing assessments into clinical evaluations may improve the understanding of sensory\u2010related challenges in this population. A multidisciplinary approach could help refine clinical management strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.70642","type":"journal-article","created":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T05:05:33Z","timestamp":1750136733000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Sensory Processing Difficulties in Children With Eosinophilic Esophagitis"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8274-8212","authenticated-orcid":false,"given":"Muserrefe Nur","family":"Keles","sequence":"first","affiliation":[{"name":"Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation Gazi University  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hacer Ilbilge","family":"Ertoy Karagol","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Pediatric Allergy Gazi University  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8007-7854","authenticated-orcid":false,"given":"Ramazan","family":"Yildiz","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation Erzurum Technical University  Erzurum Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Odul","family":"Egritas Gurkan","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Pediatric Gastroenterology Gazi University  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sinan","family":"Sari","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Pediatric Gastroenterology Gazi University  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bulent","family":"Elbasan","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation Gazi University  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Buket","family":"Dalgic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Pediatric Gastroenterology Gazi University  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arzu","family":"Bakirtas","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Pediatric Allergy Gazi University  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Gazi University Pediatric Eosinophilic Gastrointestinal Diseases Working Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,17]]},"reference":[{"key":"e_1_2_12_2_1","volume-title":"Sensory Integration and the Child","author":"Ayres A. 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