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We report an NDE in a 73\u2010year\u2010old woman with an acute exacerbation of chronic obstructive pulmonary disease, requiring emergency intubation and mechanical ventilation for acute respiratory failure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>The patient suffered from profound hypoxia and hypercapnia with uncompensated respiratory acidosis. Prehospital anesthesia was induced with an intravenous bolus of 500\u00a0mg of ketamine administered over 60 s, corresponding to 7\u00a0mg\/kg of adjusted body weight. The patient eventually recovered and was weaned from ventilator after 24 h. Semi\u2010structured interviews, including several standardized scales assessing potential subjective experience and post\u2010event impact, were conducted at 2 weeks and 2 months post\u2010event.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Finding<\/jats:title>\n                    <jats:p>Findings revealed a vivid NDE (i.e., meeting the NDE Content scale criteria, with total scores of 34\/80 and 32\/80 at the first and second interviews, respectively), notably characterized by feelings of peacefulness and well\u2010being, encounters with entities, and the perception of a bright light. Over time, the narrative evolved, with some elements no longer recalled at follow\u2010up, while the patient reported a positive psychological transformation, including improved mood and increased empathy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case, set within its medical and pharmacological context, provides a unique opportunity to study NDEs and their precipitating context. The reported transformations underscore the importance of recognizing NDEs for their possible long\u2010term effects on patients and relevance to medical practice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.70939","type":"journal-article","created":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T16:01:01Z","timestamp":1761321661000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Near\u2010Death Experience During Emergency Ketamine Use: A Case Report"],"prefix":"10.1002","volume":"15","author":[{"given":"Pauline","family":"Fritz","sequence":"first","affiliation":[{"name":"Coma Science Group, GIGA\u2010Consciousness University of Li\u00e8ge  Li\u00e8ge Belgium"},{"name":"NeuroRehab and Consciousness Clinic, Neurology department University Hospital of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana\u00efs","family":"Pichelin","sequence":"additional","affiliation":[{"name":"Coma Science Group, GIGA\u2010Consciousness University of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurore","family":"Ancion","sequence":"additional","affiliation":[{"name":"Coma Science Group, GIGA\u2010Consciousness University of Li\u00e8ge  Li\u00e8ge Belgium"},{"name":"Department of Emergency University Hospital of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naji","family":"Alnagger","sequence":"additional","affiliation":[{"name":"Coma Science Group, GIGA\u2010Consciousness University of Li\u00e8ge  Li\u00e8ge Belgium"},{"name":"NeuroRehab and Consciousness Clinic, Neurology department University Hospital of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Lejeune","sequence":"additional","affiliation":[{"name":"Coma Science Group, GIGA\u2010Consciousness University of Li\u00e8ge  Li\u00e8ge Belgium"},{"name":"NeuroRehab and Consciousness Clinic, Neurology department University Hospital of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Ghuysen","sequence":"additional","affiliation":[{"name":"Department of Emergency University Hospital of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia","family":"Gosseries","sequence":"additional","affiliation":[{"name":"Coma Science Group, GIGA\u2010Consciousness University of Li\u00e8ge  Li\u00e8ge Belgium"},{"name":"NeuroRehab and Consciousness Clinic, Neurology department University Hospital of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Martial","sequence":"additional","affiliation":[{"name":"Coma Science Group, GIGA\u2010Consciousness University of Li\u00e8ge  Li\u00e8ge Belgium"},{"name":"NeuroRehab and Consciousness Clinic, Neurology department University Hospital of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,24]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2020.09.071"},{"issue":"1","key":"e_1_2_11_3_1","first-page":"16","article-title":"An Update on the Dissociative Experiences Scale","volume":"6","author":"Carlston E. 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