{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T09:04:52Z","timestamp":1780909492028,"version":"3.54.1"},"reference-count":49,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T00:00:00Z","timestamp":1774915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T00:00:00Z","timestamp":1774915200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100012547","name":"Natural Science Foundation of Guangxi Zhuang Autonomous Region","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012547","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Memory impairment is a prevalent cognitive deficit following stroke, which can significantly impact quality of life and rehabilitation prognosis. Traditional cognitive rehabilitation therapy offers some benefits in improving memory function, its efficacy remains limited. This study investigated the effects of high\u2010frequency repetitive transcranial magnetic stimulation (rTMS) at the left parietal lobe on post\u2010stroke memory impairment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 45 patients with post\u2010stroke memory impairment were randomly divided into two groups. The rTMS group underwent 20 Hz rTMS on the left parietal lobe, while the non\u2010stimulated control group received sham stimulation. All participants underwent neuropsychological tests (including the montreal cognitive assessment (MoCA), Rey auditory verbal learning test (RAVLT), and Rey\u2010Osterrieth complex figure test (ROCF)) and functional near\u2010infrared spectroscopy (fNIRS) scans before and after intervention. fNIRS data was analyzed by functional connectivity analysis to measure changes within brain networks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After treatment, the rTMS group showed greater improvement in MoCA scores compared to baseline (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.05). Relative to the controls, the rTMS group demonstrated higher scores in delayed recall for RAVLT and ROCF (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.05), as well as significantly enhanced resting\u2010state functional connectivity (rsFC) within the prefrontal lobe and between the left prefrontal lobe and right occipital lobe (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>High\u2010frequency rTMS of the left parietal lobe effectively ameliorates memory impairment in stroke patients, and one of the possible mechanisms is the enhanced rsFC within the prefrontal lobe and between the prefrontal and occipital lobes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.71355","type":"journal-article","created":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T07:01:46Z","timestamp":1774940506000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["High\u2010Frequency Repetitive Transcranial Magnetic Stimulation on the Left Parietal Lobe Improves Post\u2010Stroke Memory Impairment: An fNIRS Study"],"prefix":"10.1002","volume":"16","author":[{"given":"Luhui","family":"Cai","sequence":"first","affiliation":[{"name":"Department of Neurological Rehabilitation Jiangbin Hospital of Guangxi Zhuang Autonomous Region  Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuye","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation The First People's Hospital of Yulin  Yulin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijiang","family":"Li","sequence":"additional","affiliation":[{"name":"Data Science with Artificial Intelligence University of Exeter  England UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peirong","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Neurological Rehabilitation Jiangbin Hospital of Guangxi Zhuang Autonomous Region  Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mindong","family":"Wei","sequence":"additional","affiliation":[{"name":"Cognitive Rehabilitation Center Jiangbin Hospital of Guangxi Zhuang Autonomous Region  Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinuo","family":"Bi","sequence":"additional","affiliation":[{"name":"Cognitive Rehabilitation Center Jiangbin Hospital of Guangxi Zhuang Autonomous Region  Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaowen","family":"Wang","sequence":"additional","affiliation":[{"name":"Cognitive Rehabilitation Center Jiangbin Hospital of Guangxi Zhuang Autonomous Region  Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenyu","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Neurological Rehabilitation Jiangbin Hospital of Guangxi Zhuang Autonomous Region  Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,31]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.883542"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2016.10.009"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978\u20100\u2010444\u201063622\u20105.00001\u20102"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2018.12.007"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/PHM.0000000000001118"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978\u20100\u201012\u2010804281\u20106.00005\u20107"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2012.02.070"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awl004"},{"issue":"2","key":"e_1_2_14_10_1","first-page":"95","article-title":"Performance on the Rey\u2010Osterrieth Complex Figure Test in Alzheimer Disease and Vascular Dementia","volume":"12","author":"Cherrier M. M.","year":"1999","journal-title":"Neuropsychiatry, Neuropsychology, and Behavioral"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/13554794.2011.588176"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002293.pub3"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2012.02.014"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978\u20100\u2010444\u201063622\u20105.00023\u20101"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2023.101919"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010020\u201071692\u20106"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3476"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2015.07.004"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11064\u2010020\u201003161\u20105"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp\u20102016\u2010314224"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhs278"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2012.01.005"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.12743"},{"key":"e_1_2_14_24_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2023.1189420"},{"key":"e_1_2_14_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/13854046.2018.1429670"},{"key":"e_1_2_14_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2017.01.004"},{"key":"e_1_2_14_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2013.06.009"},{"key":"e_1_2_14_28_1","doi-asserted-by":"publisher","DOI":"10.2147\/NDT.S467357"},{"key":"e_1_2_14_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2012.03.004"},{"key":"e_1_2_14_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/35036228"},{"key":"e_1_2_14_31_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnint.2012.00008"},{"key":"e_1_2_14_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2016.12.042"},{"key":"e_1_2_14_33_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.122.041497"},{"key":"e_1_2_14_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.13948"},{"issue":"1","key":"e_1_2_14_35_1","first-page":"149","article-title":"Evidence\u2010Based Practice Recommendations for Memory Rehabilitation","volume":"47","author":"Piras F.","year":"2011","journal-title":"European Journal of Physical and Rehabilitation Medicine"},{"key":"e_1_2_14_36_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.61.10.1545"},{"key":"e_1_2_14_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2009.03.012"},{"key":"e_1_2_14_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neures.2021.05.005"},{"key":"e_1_2_14_39_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2017.00457"},{"key":"e_1_2_14_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2005.08.020"},{"key":"e_1_2_14_41_1","doi-asserted-by":"publisher","DOI":"10.1109\/EMBC.2018.8512186"},{"key":"e_1_2_14_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2017.10.006"},{"key":"e_1_2_14_43_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/121.10.1985"},{"key":"e_1_2_14_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.22416"},{"key":"e_1_2_14_45_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1252900"},{"key":"e_1_2_14_46_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1418503111"},{"key":"e_1_2_14_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2021.06.015"},{"key":"e_1_2_14_48_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.NPh.9.4.045010"},{"key":"e_1_2_14_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2010.12.007"},{"key":"e_1_2_14_50_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD\u2010230648"}],"container-title":["Brain and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.71355","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/brb3.71355","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.71355","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T08:26:31Z","timestamp":1780907191000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/brb3.71355"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,31]]},"references-count":49,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1002\/brb3.71355"],"URL":"https:\/\/doi.org\/10.1002\/brb3.71355","archive":["Portico"],"relation":{},"ISSN":["2162-3279","2162-3279"],"issn-type":[{"value":"2162-3279","type":"print"},{"value":"2162-3279","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,31]]},"assertion":[{"value":"2025-12-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71355"}}