{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T12:55:30Z","timestamp":1791291330800,"version":"4.3.0"},"reference-count":45,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>We sought to explore outcomes at 1\u00a0year in functional neurological disorder (FND) following a neuroscience\u2010informed education and counseling assessment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with FND were assessed at a quaternary neuropsychiatry clinic in Toronto, Canada, and provided education and counseling to build insight into their FND diagnosis. Patient\u2010determined diagnostic agreement at follow\u2010up was categorized as a binary variable: (i) symptoms attributable primarily to FND or (ii) attributable to another cause (neurological disease or unknown). One\u2010year symptom status was patient\u2010reported on a 7\u2010point scale (\u22123 to +3), with scores \u22652 defined as meaningful improvement. Return to work\/school was assessed as an indicator of global improvement of functional status. Univariate tests screened variables for inclusion in multivariate logistic regression models, which evaluated associations between diagnostic agreement and other outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 282 patients with FND were assessed (mean age 38.9\u00a0\u00b1\u00a012.0\u00a0years; 80.3% female), and of these, 127 had 1\u2010year follow\u2010up data. FND subtypes included functional movement disorder (functional weakness [26.8%], hyperkinetic movement [15.7%]), seizure (15.0%), sensory (16.5%), functional cognitive disorder (7.9%), persistent postural perceptual dizziness (14.2%), and speech\/swallowing (3.9%). Diagnostic agreement was significantly associated with symptom improvement (odds ratio [OR]\u00a0=\u00a03.81, 95% CI: 1.33\u201311.71,\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a00.015) and global improvement (OR\u00a0=\u00a05.74, 95% CI: 1.11\u201337.54,\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a00.047). Psychiatric comorbidity (\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a00.026), childhood trauma (\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a00.015), and psychological triggers (\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a00.013) were associated with diagnostic agreement, while ongoing medical\/neurological workup was linked to disagreement (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Diagnostic agreement was associated with symptom improvement and return\u2010to\u2010work\/school status in FND patients who received a neuroscience\u2010informed education and counseling assessment. However, given the observational design and lack of baseline measurement of diagnostic agreement, the directionality of this relationship cannot be determined.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.71491","type":"journal-article","created":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T16:19:41Z","timestamp":1783527581000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Diagnostic Agreement and 1\u2010Year Outcomes in Functional Neurological Disorder Following Neuroscience\u2010Informed Assessment, Education, and Counseling: A Retrospective Cohort Study"],"prefix":"10.1002","volume":"16","author":[{"given":"Adriano","family":"Mollica","sequence":"first","affiliation":[{"name":"Neuropsychiatry Program, Department of Psychiatry, Sunnybrook Health Sciences Centre University of Toronto  Toronto Ontario Canada"},{"name":"Hurvitz Brain Sciences Program Sunnybrook Research Institute  Toronto 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