{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T20:46:25Z","timestamp":1782938785439,"version":"3.54.5"},"reference-count":53,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T00:00:00Z","timestamp":1780099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T00:00:00Z","timestamp":1780099200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Previous task\u2010based fMRI work in a large cohort of young adults identified nine large\u2010scale functional brain networks whose encoding\u2010related responsivity was robustly associated with individual differences in episodic memory. It remains unclear whether structural connectivity within these task\u2010fMRI\u2010defined networks explains inter\u2010individual variability in memory performance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed diffusion MRI data from 1,156 young adults who completed a picture\u2010free\u2010recall task. For each participant, we reconstructed whole\u2010brain diffusion MRI tractography and extracted within\u2010network connectivity for nine independent components previously defined by task\u2010based fMRI. Edge\u2010wise multiple regression models related within\u2010network connectivity strength to free recall performance, controlling for age and sex. False discovery rate (FDR) correction was applied across all tested edges and networks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      No associations between within\u2010network structural connectivity and memory performance survived FDR correction. Several edges showed nominal (uncorrected) associations with memory, corresponding to very small effect sizes (maximum\n                      <jats:italic>r<\/jats:italic>\n                      &lt; 0.1).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In contrast to previous findings for functional responsivity during encoding, within\u2010network structural connectivity in these functionally defined episodic memory networks is only weakly related to individual differences in memory in young healthy adults.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.71515","type":"journal-article","created":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T11:10:31Z","timestamp":1780139431000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Structural Connectivity of Functionally Defined Episodic Memory Networks: A Large\u2010Scale Connectome\u2013Behavior Study"],"prefix":"10.1002","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5225-4381","authenticated-orcid":false,"given":"Neda","family":"Ghasemi","sequence":"first","affiliation":[{"name":"Division of Cognitive Neuroscience, Department of Biomedicine University of Basel  Basel Switzerland"},{"name":"Research Cluster Molecular and Cognitive Neurosciences University of Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Coynel","sequence":"additional","affiliation":[{"name":"Division of Cognitive Neuroscience, Department of Biomedicine University of Basel  Basel Switzerland"},{"name":"Research Cluster Molecular and Cognitive Neurosciences University of Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Papassotiropoulos","sequence":"additional","affiliation":[{"name":"Research Cluster Molecular and Cognitive Neurosciences University of Basel  Basel Switzerland"},{"name":"Division of Molecular Neuroscience, Department of Biomedicine University of Basel  Basel Switzerland"},{"name":"University Psychiatric Clinics University of Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique J. F.","family":"de Quervain","sequence":"additional","affiliation":[{"name":"Division of Cognitive Neuroscience, Department of Biomedicine University of Basel  Basel Switzerland"},{"name":"Research Cluster Molecular and Cognitive Neurosciences University of Basel  Basel Switzerland"},{"name":"University Psychiatric Clinics University of Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,30]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fninf.2014.00014"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.951076"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2016.06.058"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2015.10.019"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.3001275"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2016.00292"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.media.2023.102789"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.721"},{"key":"e_1_2_12_10_1","unstructured":"Dhollander T.2019. \u201cImproved White Matter Response Function Estimation for 3\u2010Tissue Constrained Spherical Deconvolution.\u201d In27th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM) 555. ISMRMhttps:\/\/archive.ismrm.org\/2019\/0555.html."},{"key":"e_1_2_12_11_1","unstructured":"Dhollander T. D.Raffelt andA.Connelly.2016. \u201cUnsupervised 3\u2010Tissue Response Function Estimation from Single\u2010Shell or Multi\u2010Shell Diffusion Mr Data Without a Co\u2010Registered T1 Image.\u201d InProceedings of the International Society for Magnetic Resonance in Medicine 5. ISMRM.https:\/\/cds.ismrm.org\/protected\/18MProceedings\/PDFfiles\/1570.html."},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2011.12.016"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0493\u201016.2016"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhv102"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2023.108723"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fninf.2014.00008"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010023\u201041380\u2010w"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.3389\/fninf.2011.00013"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291722004007"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010021\u201025184\u20104"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ibneur.2024.01.016"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0811168106"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2022.119474"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2013.09.069"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1101\/lm.919109"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/braincomms\/fcaf048"},{"key":"e_1_2_12_27_1","unstructured":"Lang P. J. M. M.Bradley andB. N.Cuthbert.2008.International Affective Picture System (IAPS): Affective Ratings of Pictures and Instruction Manual (Technical Report A\u20108 University of Florida)."},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1177\/1352458518771838"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2012.00056"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010022\u201004492\u20109"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0270592"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.5603\/fm.93251"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2317\u201011.2011"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhw089"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2011.10.001"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2021.04.050"},{"key":"e_1_2_12_37_1","unstructured":"Raffelt D. T.Dhollander J.\u2010D.Tournier et\u00a0al.2017. \u201cBias Field Correction and Intensity Normalisation for Quantitative Analysis of Apparent Fibre Density.\u201d InProceedings of the International Society for Magnetic Resonance in Medicine 3541.ISMRM.https:\/\/archive.ismrm.org\/2017\/3541.html."},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1162\/imag_a_00416"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429\u2010019\u201001945\u20102"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnana.2023.1240545"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429\u2010020\u201002129\u2010z"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.20.1.11"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.52294\/ApertureNeuro.2022.2.NEOD9565"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1523\/ENEURO.0418\u201023.2023"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.3752"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.26465"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1162\/jocn.2008.20104"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2004.07.037"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2019.116137"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2008.05.002"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2010.2046908"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1101\/lm.048199.118"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1903403116"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2016.08.016"}],"container-title":["Brain and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.71515","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/brb3.71515","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.71515","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T20:30:46Z","timestamp":1782937846000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/brb3.71515"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,30]]},"references-count":53,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1002\/brb3.71515"],"URL":"https:\/\/doi.org\/10.1002\/brb3.71515","archive":["Portico"],"relation":{},"ISSN":["2162-3279","2162-3279"],"issn-type":[{"value":"2162-3279","type":"print"},{"value":"2162-3279","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,30]]},"assertion":[{"value":"2026-01-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71515"}}