{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T13:30:19Z","timestamp":1789047019203,"version":"build-2803163510"},"reference-count":155,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T00:00:00Z","timestamp":1786752000000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Ischemic stroke poses a major global health burden, and growing evidence points to the microbiota\u2013gut\u2013brain axis as an important contributor to stroke pathophysiology and recovery. The purpose of this review is to summarize current knowledge on bidirectional gut\u2010brain communication in stroke, establishing gut dysbiosis as an upstream risk factor for stroke onset and examining microbiota dynamics across acute and chronic phases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A comprehensive review of the current literature was conducted to synthesize existing evidence on the mechanisms of gut\u2010brain communication, the influence of host factors, post\u2010stroke complications, and candidate therapeutic interventions targeting the MGBA in ischemic stroke.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Finding<\/jats:title>\n                    <jats:p>\n                      Gut dysbiosis acts as a risk factor for stroke through TMAO\u2010mediated atherothrombosis, systemic inflammatory priming, and comorbidity\u2010associated dysbiotic pre\u2010conditioning. Following a stroke, dysbiosis is characterized by a depletion of short\u2010chain fatty acid (SCFA)\u2010producing taxa and an expansion of pro\u2010inflammatory bacteria, particularly\u00a0\n                      <jats:italic>Proteobacteria<\/jats:italic>\n                      \u00a0and\u00a0\n                      <jats:italic>Enterobacteriaceae<\/jats:italic>\n                      . Host factors (age, sex, genetics, and comorbidities) shape microbiota signatures and influence outcomes. Furthermore, post\u2010stroke complications\u2014including cognitive impairment, depression, stroke\u2010associated pneumonia, and gastrointestinal dysfunction\u2014are intimately linked to persistent dysbiosis. Mechanistically, the gut microbiota modulates stroke outcomes through immune regulation, metabolite signaling, blood\u2013brain barrier integrity, and vagal pathways. Candidate therapeutic interventions (probiotics\/prebiotics, fecal microbiota transplantation, SCFA supplementation, traditional Chinese medicine, and neuromodulation) demonstrate promising neuroprotective and recovery\u2010enhancing effects, predominantly in preclinical models.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>While targeted interventions like probiotics and dietary fiber supplementation have shown modest benefits in small clinical trials, human clinical evidence remains largely preliminary. The translation of FMT, SCFA supplementation, and neuromodulatory approaches to clinical practice requires validation through rigorous, adequately powered randomized controlled trials. Future precision microbiome medicine demands individualized profiling and phenotype\u2010specific interventions to establish microbiota\u2010targeted strategies as viable adjunctive stroke therapies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.71547","type":"journal-article","created":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T16:02:49Z","timestamp":1786809769000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Gut Microbiota and Ischemic Stroke: From Pre\u2010Stroke Dysbiosis and Acute\u2010Phase Changes to Therapeutic Applications"],"prefix":"10.1002","volume":"16","author":[{"given":"Ruihui","family":"Weng","sequence":"first","affiliation":[{"name":"Department of Neurology, National Clinical Research Center For Infectious Diseases The Third People's Hospital of Shenzhen  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaolei","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Clinical Research Center For Infectious Diseases The Third People's Hospital of Shenzhen  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianxin","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Liver Surgery &amp; Liver Transplantation Center, National Clinical Research Center For Infectious Diseases The Third People's Hospital of Shenzhen  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Clinical Research Center For Infectious Diseases The Third People's Hospital of Shenzhen  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,15]]},"reference":[{"key":"e_1_2_18_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2020.02.001"},{"key":"e_1_2_18_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msad216"},{"key":"e_1_2_18_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu17152538"},{"key":"e_1_2_18_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4068"},{"key":"e_1_2_18_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-020-01833-1"},{"key":"e_1_2_18_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtha.2024.06.028"},{"key":"e_1_2_18_8_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3009759"},{"key":"e_1_2_18_9_1","doi-asserted-by":"publisher","DOI":"10.2147\/NDT.S415098"},{"key":"e_1_2_18_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24021806"},{"key":"e_1_2_18_11_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI143771"},{"key":"e_1_2_18_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X221107702"},{"key":"e_1_2_18_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2025.157476"},{"key":"e_1_2_18_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2022.1073113"},{"key":"e_1_2_18_15_1","doi-asserted-by":"publisher","DOI":"10.1128\/msystems.00185-24"},{"key":"e_1_2_18_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30211-7"},{"key":"e_1_2_18_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.123.033221"},{"key":"e_1_2_18_18_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00661"},{"key":"e_1_2_18_19_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000479"},{"key":"e_1_2_18_20_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-nutr-082018-124344"},{"key":"e_1_2_18_21_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.528056"},{"key":"e_1_2_18_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.15770"},{"key":"e_1_2_18_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-023-02887-7"},{"key":"e_1_2_18_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/cns.14271"},{"key":"e_1_2_18_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2022.01.025"},{"key":"e_1_2_18_26_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/1469339"},{"key":"e_1_2_18_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2018.10.022"},{"key":"e_1_2_18_28_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2024.1378844"},{"key":"e_1_2_18_29_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.123.042755"},{"key":"e_1_2_18_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2024.106423"},{"key":"e_1_2_18_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-023-00874-w"},{"key":"e_1_2_18_32_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu16030390"},{"key":"e_1_2_18_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13293-020-00352-1"},{"key":"e_1_2_18_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2019.104349"},{"key":"e_1_2_18_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4030"},{"key":"e_1_2_18_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-020-0433-9"},{"key":"e_1_2_18_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2015.09.001"},{"key":"e_1_2_18_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4476"},{"key":"e_1_2_18_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature12721"},{"key":"e_1_2_18_40_1","doi-asserted-by":"publisher","DOI":"10.1093\/advances\/nmz127"},{"key":"e_1_2_18_41_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2021.701355"},{"key":"e_1_2_18_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mimet.2023.106846"},{"key":"e_1_2_18_43_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/5596924"},{"key":"e_1_2_18_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12975-020-00863-4"},{"key":"e_1_2_18_45_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.118.311023"},{"key":"e_1_2_18_46_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1324018"},{"key":"e_1_2_18_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11883-025-01381-0"},{"key":"e_1_2_18_48_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.797302"},{"key":"e_1_2_18_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)00642-1"},{"key":"e_1_2_18_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2020.07.012"},{"key":"e_1_2_18_51_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.122.319983"},{"key":"e_1_2_18_52_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-021-01181-z"},{"key":"e_1_2_18_53_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000034764"},{"key":"e_1_2_18_54_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-025-03689-9"},{"key":"e_1_2_18_55_1","doi-asserted-by":"publisher","DOI":"10.14336\/AD.2022.0916"},{"key":"e_1_2_18_56_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu14010166"},{"key":"e_1_2_18_57_1","doi-asserted-by":"publisher","DOI":"10.1038\/s44161-022-00197-4"},{"key":"e_1_2_18_58_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.02167"},{"key":"e_1_2_18_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2024.114834"},{"key":"e_1_2_18_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2023.03.032"},{"key":"e_1_2_18_61_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2021.663967"},{"key":"e_1_2_18_62_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12031-023-02149-4"},{"key":"e_1_2_18_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00126-9"},{"key":"e_1_2_18_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12975-022-01005-8"},{"key":"e_1_2_18_65_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-023-03504-7"},{"key":"e_1_2_18_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2020.105277"},{"key":"e_1_2_18_67_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.119.316448"},{"key":"e_1_2_18_68_1","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2023.2271629"},{"key":"e_1_2_18_69_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.020646"},{"key":"e_1_2_18_70_1","doi-asserted-by":"publisher","DOI":"10.1515\/tnsci-2020-0117"},{"key":"e_1_2_18_71_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-016-0222-x"},{"key":"e_1_2_18_72_1","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci13081217"},{"key":"e_1_2_18_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2023.106714"},{"key":"e_1_2_18_74_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2020.511562"},{"key":"e_1_2_18_75_1","doi-asserted-by":"publisher","DOI":"10.18632\/aging.102846"},{"key":"e_1_2_18_76_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13020-024-00991-1"},{"key":"e_1_2_18_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-021-00992-y"},{"key":"e_1_2_18_78_1","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2022.2126272"},{"key":"e_1_2_18_79_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.19159"},{"key":"e_1_2_18_80_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-023-02957-w"},{"key":"e_1_2_18_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2022.e12605"},{"key":"e_1_2_18_82_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2022\/2124230","article-title":"Exercise Preconditioning Ameliorates Cognitive Impairment in Mice With Ischemic Stroke by Alleviating Inflammation and Modulating Gut Microbiota","volume":"2022","author":"Lv H.","year":"2022","journal-title":"Mediators of Inflammation"},{"key":"e_1_2_18_83_1","doi-asserted-by":"publisher","DOI":"10.1080\/1028415X.2023.2242121"},{"key":"e_1_2_18_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jare.2023.02.006"},{"key":"e_1_2_18_85_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms12010037"},{"key":"e_1_2_18_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2020.01.010"},{"key":"e_1_2_18_87_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox13080985"},{"key":"e_1_2_18_88_1","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.70017"},{"key":"e_1_2_18_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.02.016"},{"key":"e_1_2_18_90_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000001350"},{"key":"e_1_2_18_91_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.118.021997"},{"key":"e_1_2_18_92_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-017-2673-z"},{"key":"e_1_2_18_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2025.103908"},{"key":"e_1_2_18_94_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-024-01136-9"},{"key":"e_1_2_18_95_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2015.00080"},{"key":"e_1_2_18_96_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00248-022-02081-x"},{"key":"e_1_2_18_97_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12975-019-00760-5"},{"key":"e_1_2_18_98_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-57014-2"},{"key":"e_1_2_18_99_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.121.036800"},{"key":"e_1_2_18_100_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22020915"},{"key":"e_1_2_18_101_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.120.030643"},{"key":"e_1_2_18_102_1","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.3387"},{"key":"e_1_2_18_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2021.11.016"},{"key":"e_1_2_18_104_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1114-16.2016"},{"key":"e_1_2_18_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresbull.2024.110888"},{"key":"e_1_2_18_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbih.2021.100318"},{"key":"e_1_2_18_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2023.12.010"},{"key":"e_1_2_18_108_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.25250"},{"key":"e_1_2_18_109_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4194"},{"key":"e_1_2_18_110_1","doi-asserted-by":"publisher","DOI":"10.1111\/cns.14089"},{"key":"e_1_2_18_111_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23031172"},{"key":"e_1_2_18_112_1","doi-asserted-by":"publisher","DOI":"10.1002\/jpen.1861"},{"key":"e_1_2_18_113_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1109400"},{"key":"e_1_2_18_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2024.115111"},{"key":"e_1_2_18_115_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xcrm.2024.101754"},{"key":"e_1_2_18_116_1","doi-asserted-by":"publisher","DOI":"10.1128\/Spectrum.00042-21"},{"key":"e_1_2_18_117_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-022-02435-9"},{"key":"e_1_2_18_118_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-022-02606-8"},{"key":"e_1_2_18_119_1","doi-asserted-by":"publisher","DOI":"10.2147\/JIR.S350109"},{"key":"e_1_2_18_120_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.121.316533"},{"key":"e_1_2_18_121_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000012805"},{"key":"e_1_2_18_122_1","doi-asserted-by":"publisher","DOI":"10.1002\/cns.70704"},{"key":"e_1_2_18_123_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2022.980722"},{"key":"e_1_2_18_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2024.112030"},{"key":"e_1_2_18_125_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2019-320204"},{"key":"e_1_2_18_126_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-024-05800-9"},{"issue":"12","key":"e_1_2_18_127_1","first-page":"717","article-title":"Elevated Phenylacetylglutamine Caused by Gut Dysbiosis Associated With Type 2 Diabetes Increases Neutrophil Extracellular Traps Formation and Exacerbates Brain Infarction","volume":"139","author":"Wei M.","year":"2025","journal-title":"Clinical Science"},{"key":"e_1_2_18_128_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000005298"},{"key":"e_1_2_18_129_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2024.107229"},{"key":"e_1_2_18_130_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00397"},{"key":"e_1_2_18_131_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2021.715475"},{"key":"e_1_2_18_132_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2020.587284"},{"key":"e_1_2_18_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2021.08.045"},{"key":"e_1_2_18_134_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-020-00923-9"},{"key":"e_1_2_18_135_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2020-323263"},{"key":"e_1_2_18_136_1","doi-asserted-by":"publisher","DOI":"10.1159\/000516398"},{"key":"e_1_2_18_137_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.25742"},{"key":"e_1_2_18_138_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2023.1116065"},{"key":"e_1_2_18_139_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature11053"},{"key":"e_1_2_18_140_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.115.002699"},{"key":"e_1_2_18_141_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2023.1327499"},{"key":"e_1_2_18_142_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2025.107685"},{"key":"e_1_2_18_143_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.707972"},{"key":"e_1_2_18_144_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2023.11.021"},{"key":"e_1_2_18_145_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2024.1334581"},{"key":"e_1_2_18_146_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2026.1749522"},{"key":"e_1_2_18_147_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1107559"},{"key":"e_1_2_18_148_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2024.155530"},{"key":"e_1_2_18_149_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12975-022-01096-3"},{"issue":"24","key":"e_1_2_18_150_1","first-page":"12993","article-title":"Associations of OSAHS Complicated by Cerebral Infarction With Intestinal Flora, Inflammatory Factors, Homocysteine and Adiponectin Expression","volume":"24","author":"Zhang W. T.","year":"2020","journal-title":"European Review for Medical and Pharmacological Sciences"},{"key":"e_1_2_18_151_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.836820"},{"key":"e_1_2_18_152_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2022.e11848"},{"key":"e_1_2_18_153_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2023.1081347"},{"key":"e_1_2_18_154_1","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgaf340"},{"key":"e_1_2_18_155_1","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X20910533"},{"key":"e_1_2_18_156_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2021.05.002"}],"container-title":["Brain and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.71547","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/brb3.71547","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.71547","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T13:03:45Z","timestamp":1789045425000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/brb3.71547"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":155,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1002\/brb3.71547"],"URL":"https:\/\/doi.org\/10.1002\/brb3.71547","archive":["Portico"],"relation":{},"ISSN":["2162-3279","2162-3279"],"issn-type":[{"value":"2162-3279","type":"print"},{"value":"2162-3279","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"2026-01-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71547"}}