{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T13:30:01Z","timestamp":1789047001940,"version":"build-2803163510"},"reference-count":52,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82471544"],"award-info":[{"award-number":["82471544"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82271569"],"award-info":[{"award-number":["82271569"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Suicidal ideation (SI) is common in major depressive disorder (MDD) and has been linked to sleep disturbances. However, the relative contributions of subjective sleep quality and objective sleep architecture to SI remain unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A total of 103 inpatients with MDD underwent polysomnography (PSG) and completed the Pittsburgh Sleep Quality Index (PSQI). Based on HAMD\u201017 item 3 scores, participants were classified into SI (\n                      <jats:italic>n<\/jats:italic>\n                      = 49) and non\u2010SI (N\u2010SI,\n                      <jats:italic>n<\/jats:italic>\n                      = 54) groups. Clinical characteristics, subjective sleep quality, and PSG\u2010derived sleep parameters were compared between groups. Binary logistic regression was performed to identify independent predictors of SI.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Compared with the N\u2010SI group, patients with SI had longer illness duration, more depressive episodes, higher depressive severity, and poorer subjective sleep quality. PSG analyses revealed that SI patients showed significantly lower N3% and higher apnea\u2013hypopnea index (AHI). Logistic regression indicated that PSQI score, N3%, and AHI were independent predictors of SI. A combined model incorporating these three factors demonstrated excellent discriminative ability (AUC = 0.924) for identifying SI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Both subjective sleep disturbance and objective sleep abnormalities, specifically reduced slow\u2010wave sleep and elevated AHI, are strongly associated with SI in MDD. Integrating subjective and objective sleep assessments may enhance suicide risk detection and guide targeted interventions for prevention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.71693","type":"journal-article","created":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:37:52Z","timestamp":1787031472000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Reduced Slow\u2010Wave Sleep and Sleep\u2010Disordered Breathing Are Linked to Suicidal Ideation in Major Depressive Disorder"],"prefix":"10.1002","volume":"16","author":[{"given":"Limin","family":"Yang","sequence":"first","affiliation":[{"name":"Shandong Mental Health Center Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Wang","sequence":"additional","affiliation":[{"name":"Peking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital)  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renyun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Shandong Mental Health Center Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shilong","family":"Jia","sequence":"additional","affiliation":[{"name":"Shandong Mental Health Center Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuefei","family":"Wu","sequence":"additional","affiliation":[{"name":"Shandong Mental Health Center Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun'ai","family":"Su","sequence":"additional","affiliation":[{"name":"Peking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital)  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jitao","family":"Li","sequence":"additional","affiliation":[{"name":"Peking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital)  Beijing 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