{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T07:44:07Z","timestamp":1792395847521,"version":"4.4.0"},"reference-count":49,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:00:00Z","timestamp":1789603200000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Multiple sclerosis (MS) is a chronic neurodegenerative disorder associated with diverse physical and psychological challenges. Effective self\u2010care behaviors are essential for managing symptoms and improving quality of life. Psychological constructs such as self\u2010compassion and illness perception are key determinants of self\u2010management in chronic illness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study investigated the role of self\u2010compassion in promoting self\u2010care behaviors among patients with MS, emphasizing the mediating role of illness perception based on Leventhal's Common\u2010Sense Model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A cross\u2010sectional analytical study was conducted among 360 patients with MS referred to Sina Hospital, Tehran. Participants completed the\n                      <jats:italic>Self\u2010Care of Chronic Illness Inventory (Version 4.c)<\/jats:italic>\n                      ,\n                      <jats:italic>Revised Illness Perception Questionnaire (IPQ\u2010R)<\/jats:italic>\n                      , and\n                      <jats:italic>Self\u2010Compassion Scale (SCS)<\/jats:italic>\n                      . Structural equation modeling (SEM) was used to examine direct and indirect relationships between self\u2010compassion, illness perception dimensions, and self\u2010care behaviors. Model fit was evaluated using\n                      <jats:italic>\u03c7<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \/df\u00a0=\u00a02.52, CFI\u00a0=\u00a00.843, TLI\u00a0=\u00a00.825, RMSEA\u00a0=\u00a00.065, and SRMR\u00a0=\u00a00.084.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Self\u2010compassion had a significant positive direct effect on self\u2010care (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a00.30,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.006). Indirect effects were also found through personal control (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a00.15,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.004), emotional representation (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a00.22,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.011), and illness coherence (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a00.15,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.030). Other illness perception dimensions, including treatment control and timeline beliefs, did not show significant mediation effects (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&gt;\u00a00.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Self\u2010compassion promotes self\u2010care behaviors in MS patients both directly and indirectly by enhancing adaptive illness perceptions\u2014particularly personal control, illness coherence, and emotional balance. Interventions aimed at fostering self\u2010compassion and reframing maladaptive illness perceptions may strengthen disease self\u2010management and psychological well\u2010being.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.71772","type":"journal-article","created":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T06:15:58Z","timestamp":1789712158000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Role of Self\u2010Compassion on Self\u2010Care With the Mediating Role of Illness Perception in Patients With Multiple Sclerosis Referred to Sina Hospital: Based on the Leventhal Model"],"prefix":"10.1002","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-8326-5769","authenticated-orcid":false,"given":"Ali","family":"Bagheri","sequence":"first","affiliation":[{"name":"Department of Clinical Psychology, School of Medicine Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8686-523X","authenticated-orcid":false,"given":"Amir Sam","family":"Kianimoghadam","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology, School of Medicine Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2302-3574","authenticated-orcid":false,"given":"Zahra","family":"Ebadi","sequence":"additional","affiliation":[{"name":"Multiple Sclerosis Research Center, Neuroscience Institute Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2474-3381","authenticated-orcid":false,"given":"Abbas","family":"Masjedi\u2010Arani","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology, School of Medicine Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6136-0697","authenticated-orcid":false,"given":"Maryam","family":"Amini\u2010Fasakhoudi","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology, School of Medicine Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,17]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5369"},{"issue":"3","key":"e_1_2_10_3_1","first-page":"149","article-title":"The Validity and Reliability of the Iranian Version of the Self\u2010Compassion Scale","volume":"1","author":"Azizi A.","year":"2013","journal-title":"Practice in Clinical Psychology"},{"key":"e_1_2_10_4_1","unstructured":"Bagheri A. 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