{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T09:02:16Z","timestamp":1790326936650,"version":"4.1.0"},"reference-count":41,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Meaning in life is a fundamental component of mental health that can be influenced by early traumatic experiences. This study aimed to investigate the mediating role of self\u2010compassion in the relationship between childhood trauma and meaning in life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>This cross\u2010sectional study utilized a correlational design and structural equation modeling (SEM) approach. The study population included individuals aged 18 to 60 residing in Semnan in 2025, with 562 participants recruited through convenience sampling and voluntarily participating in the research (216 men [38.4%], 346 women [61.6%]; M = 40.00, SD = 7.93) The research instruments included the Childhood Trauma Questionnaire (CTQ), the Self\u2010Compassion Scale (SCS), and the Meaning in Life Questionnaire (MLQ). Data were analyzed using SPSS 26 and Smart\u2010PLS 4 software.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>\n                      The results indicated that childhood trauma had a significant negative effect on self\u2010compassion (\u03b2 = \u22120.462) and meaning in life (\u03b2 = \u22120.224). Additionally, self\u2010compassion showed a significant positive relationship with meaning in life (\u03b2 = 0.454). The analysis of indirect effects revealed that self\u2010compassion plays a significant mediating role in the relationship between childhood trauma and meaning in life (\u03b2 = \u22120.210,\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The findings suggest that self\u2010compassion can help maintain and enhance meaning in life by reducing the negative consequences of childhood trauma. These results underscore the importance of interventions aimed at fostering self\u2010compassion in individuals with early traumatic experiences.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.71800","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T05:59:25Z","timestamp":1790229565000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Association Between Childhood Trauma and Meaning in Life: The Mediating Role of Self\u2010Compassion in Iranian Adults"],"prefix":"10.1002","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-6381-1779","authenticated-orcid":false,"given":"Reza","family":"Refaei","sequence":"first","affiliation":[{"name":"Department of Clinical Psychology, Faculty of Medical Sciences Islamic Azad University  Semnan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,23]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijop.12709"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.24869\/psyd.2024.351"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2023.1180082"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0145\u20102134(02)00541\u20100"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12671\u2010022\u201001891\u2010x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"crossref","unstructured":"\u00c7i\u00e7ek \u0130.2025. \u201cRelationship between Adverse Childhood Experiences and Anxiety Symptoms Among Youth: The Mediating Roles of Positive Childhood Experiences and Meaning in Life.\u201dJournal of Interpersonal Violence ahead of print May 30.https:\/\/doi.org\/10.1177\/08862605251399674.","DOI":"10.1177\/08862605251399674"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11126\u2010026\u201010286\u20103"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chiabu.2023.106089"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.2466\/PR0.104.2.509\u2010516"},{"key":"e_1_2_10_11_1","unstructured":"Gentry M. 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W.Palmer.2025. \u201cFrom Adversity to Purpose: How Self\u2010Compassion and Age Influence Meaning in Life Among Adults With Adverse Childhood Experiences.\u201dJournal of Adult Development ahead of print June 18.https:\/\/doi.org\/10.1007\/s10804\u2010025\u201009547\u20105."},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/01612840.2016.1253804"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.25215\/0303.186"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev\u2010psych\u2010072420\u2010122921"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/08862605211062994"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40359\u2010025\u201002746\u20105"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/17439760.2015.1137623"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadr.2020.100023"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2025.106124"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/15298860309027"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.paid.2021.111360"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1177\/00846724221150027"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.21859\/sija.12.3.326"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.22055\/psy.2025.50012.3452"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/jopy.12820"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12144\u2010021\u201002206\u20104"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1080\/10720537.2015.1119080"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1177\/17423953221150686"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2022.1059330"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022-0167.53.1.80"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1080\/10720537.2020.1865854"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2015.08.015"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chiabu.2011.07.003"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2021.05.019"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00406\u2010024\u201001779\u2010y"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s44202\u2010025\u201000383\u2010y"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2017.02.026"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12144\u2010022\u201004031\u20109"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chiabu.2018.03.013"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.281053"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1177\/001316447403400104"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1177\/15248380211043825"}],"container-title":["Brain and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.71800","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/brb3.71800","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.71800","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T08:11:58Z","timestamp":1790323918000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/brb3.71800"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":41,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1002\/brb3.71800"],"URL":"https:\/\/doi.org\/10.1002\/brb3.71800","archive":["Portico"],"relation":{},"ISSN":["2162-3279","2162-3279"],"issn-type":[{"value":"2162-3279","type":"print"},{"value":"2162-3279","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"2026-06-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71800"}}