{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T17:50:45Z","timestamp":1792173045709,"version":"4.4.0"},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:00:00Z","timestamp":1792108800000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100025520","name":"Medical Research Future Fund","doi-asserted-by":"publisher","award":["APP2012410"],"award-info":[{"award-number":["APP2012410"]}],"id":[{"id":"10.13039\/501100025520","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Psilocybin is a naturally occurring classic psychedelic associated with widespread changes in brain function and promising therapeutic outcomes in several neuropsychiatric disorders. Complementing these findings, qualitative studies following psilocybin administration have revealed diverse and highly individual effects across multiple domains of subjective experience. However, little is known about its impacts on individuals\u2019 subjective motor experiences. With the tendency of individuals to stay stationary during psilocybin's effects, investigating qualitative motor experiences following low\u2010to\u2010moderate doses of psilocybin may offer novel considerations regarding safety and quality of individuals\u2019 psychedelic experiences. We aimed to explore healthy individuals\u2019 subjective experiences after receiving three different doses of psilocybin and conducting motor activity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Following the study procedure previously published, semi\u2010structured interviews were conducted with 12 participants who had completed sessions of motor tasks at different doses of psilocybin, which were then transcribed and thematically analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Four major themes were developed, each containing sub\u2010themes: two motor themes, (1) mixed motor messages, including altered motor coordination, control, speed, and reaction time; (2) interacting influences on motor performance, including dose\u2010dependent effects; and two non\u2010motor themes, (3) transcendence, altered consciousness, and transformative \u201cmysticism\u201d; and (4) dynamic and enhanced psychological and sensory experiences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This work contributes to a more comprehensive understanding of psilocybin's multifaceted effects and their relevance to safety, therapeutic potential and future research in motor disorders. The findings will inform a broader dose\u2010finding study and the design of proposed research on psilocybin\u2010assisted physiotherapy for refractory motor functional neurological disorder.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>ANZCTR number: ACTRN12621000560897<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.71807","type":"journal-article","created":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T17:12:50Z","timestamp":1792170770000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["After the Trip: A Qualitative Study of Healthy Individuals\u2019 Motor Experiences Following Different Doses of Psilocybin"],"prefix":"10.1002","volume":"16","author":[{"given":"Ruiqi Rachel","family":"Luo","sequence":"first","affiliation":[{"name":"Department of Psychiatry Austin Health University of Melbourne  Heidelberg Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Berlowitz","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy University of Melbourne  Parkville Victoria Australia"},{"name":"Institute For Breathing and Sleep Austin Health  Heidelberg Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Bryson","sequence":"additional","affiliation":[{"name":"Florey Institute of Neuroscience &amp; Mental Health University of Melbourne  Parkville Victoria Australia"},{"name":"Department of Neurology Royal Melbourne Hospital  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia","family":"Carter","sequence":"additional","affiliation":[{"name":"Melbourne School of Psychological Sciences University of Melbourne  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiranth","family":"Bhagavan","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Austin Health University of Melbourne  Heidelberg Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Kanaan","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Austin Health University of Melbourne  Heidelberg Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,16]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380\u2010023\u201002360\u20100"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/acps.13249"},{"key":"e_1_2_13_4_1","unstructured":"ANZCTR.2025. \u201cSafety and Tolerability of Psilocybin\u2010Assisted Physiotherapy in Healthy Volunteers.\u201d NHMRC Clinical Trials Centre. Accessed May 20.https:\/\/www.anzctr.org.au\/Trial\/Registration\/TrialReview.aspx?id=381526."},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022167817706884"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1017\/neu.2025.10042"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40263\u2010026\u201001326\u20104"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.prcp.20240047"},{"key":"e_1_2_13_9_1","volume-title":"Successful Qualitative Research: A Practical Guide for Beginners","author":"Braun V.","year":"2013"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1191\/1478088706qp063oa"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40263\u2010020\u201000748\u2010y"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s44184\u2010024\u201000095\u20106"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ijnp\/pyx011"},{"key":"e_1_2_13_14_1","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2021.724606","article-title":"Psychedelics and Neuroplasticity: A Systematic Review Unraveling the Biological Underpinnings of Psychedelics","volume":"12","author":"De Vos C. 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