{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T05:04:55Z","timestamp":1790831095855,"version":"4.1.0"},"reference-count":29,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LGC22H090001"],"award-info":[{"award-number":["LGC22H090001"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This exploratory pilot study aimed to examine the potential effects of a shortened, individually delivered dialectical behavior therapy (DBT)\u2010based intervention added to pharmacotherapy on suicide\u2010related outcomes among Chinese outpatients with affective disorders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Twenty\u2010one participants recruited from the psychiatric outpatient clinics of the First Affiliated Hospital, School of Medicine, Zhejiang University, were randomly assigned to two groups. Participants in the research group received pharmacotherapy plus a shortened, individually delivered DBT\u2010based intervention, whereas those in the control group received pharmacotherapy alone. Participants completed baseline assessments, 12 weeks of treatment, and 12 weeks of follow\u2010up, with assessments performed every 4 weeks. Outcomes included suicide risk or severity, depression, anxiety, and hopelessness assessed using self\u2010report scales.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After adjustment for baseline values using repeated\u2010measures analysis of covariance (RM\u2010ANCOVA), the between\u2010group effect on suicide risk showed a marginal trend favoring the DBT\u2010based psychotherapy group, but did not reach conventional statistical significance (\n                      <jats:italic>F<\/jats:italic>\n                      = 4.26,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.054). The time effect (\n                      <jats:italic>F<\/jats:italic>\n                      = 0.234,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.965) and time\u2010by\u2010group interaction (\n                      <jats:italic>F<\/jats:italic>\n                      = 1.306,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.261) for suicide risk were not statistically significant. Depressive symptoms showed a significant time effect across the follow\u2010up period, whereas most suicide\u2010related and hopelessness outcomes were not statistically significant. These findings should be interpreted as preliminary because of the small sample size and baseline imbalance.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The results provided preliminary pilot evidence that a shortened DBT\u2010based intervention may be feasible and potentially beneficial as an adjunct to pharmacotherapy in this clinical population. However, the primary suicide\u2010risk outcome did not show a statistically significant between\u2010group effect. Larger adequately powered trials with baseline\u2010adjusted analyses and more comprehensive outcome assessment are needed before firm conclusions can be drawn.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.71827","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:49:28Z","timestamp":1790830168000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Application of an Exploratory DBT\u2013Based Psychotherapy Program for Suicide\u2010Related Symptoms in Chinese Outpatients With Affective Disorders"],"prefix":"10.1002","volume":"16","author":[{"given":"Chanchan","family":"Hu","sequence":"first","affiliation":[{"name":"The First Affiliated Hospital Zhejiang University School of Medicine  Hangzhou China"},{"name":"The Key Laboratory of Mental Disorder's Management of Zhejiang Province  Hangzhou China"},{"name":"Department of Radiology, The First Affiliated Hospital, The Key Laboratory of Mental Disorder's Management of Zhejiang Province Zhejiang University School of Medicine  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingkai","family":"Chen","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital Zhejiang University School of Medicine  Hangzhou China"},{"name":"The Key Laboratory of Mental Disorder's Management of Zhejiang Province  Hangzhou China"},{"name":"Department of Radiology, The First Affiliated Hospital, The Key Laboratory of Mental Disorder's Management of Zhejiang Province Zhejiang University School of Medicine  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhong","family":"Wang","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital Zhejiang University School of Medicine  Hangzhou China"},{"name":"The Key Laboratory of Mental Disorder's Management of Zhejiang Province  Hangzhou China"},{"name":"Department of Radiology, The First Affiliated Hospital, The Key Laboratory of Mental Disorder's Management of Zhejiang Province Zhejiang University School of Medicine  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyi","family":"Zhou","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital Zhejiang University School of Medicine  Hangzhou China"},{"name":"The Key Laboratory of Mental Disorder's Management of Zhejiang Province  Hangzhou China"},{"name":"Department of Radiology, The First Affiliated Hospital, The Key Laboratory of Mental Disorder's Management of Zhejiang Province Zhejiang University School of Medicine  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujin","family":"Yang","sequence":"additional","affiliation":[{"name":"Oberlin College and Conservatory  Oberlin Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuguang","family":"Li","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital Zhejiang University School of Medicine  Hangzhou China"},{"name":"The Key Laboratory of Mental Disorder's Management of Zhejiang Province  Hangzhou China"},{"name":"Department of Radiology, The First Affiliated Hospital, The Key Laboratory of Mental Disorder's Management of Zhejiang Province Zhejiang University School of Medicine  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruili","family":"Zhang","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital Zhejiang University School of Medicine  Hangzhou China"},{"name":"The Key Laboratory of Mental Disorder's Management of Zhejiang Province  Hangzhou China"},{"name":"Department of Radiology, The First Affiliated Hospital, The Key Laboratory of Mental Disorder's Management of Zhejiang Province Zhejiang University School of Medicine  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianbo","family":"Lai","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital Zhejiang University School of Medicine  Hangzhou China"},{"name":"The Key Laboratory of Mental Disorder's Management of Zhejiang Province  Hangzhou China"},{"name":"Department of Radiology, The First Affiliated Hospital, The Key Laboratory of Mental Disorder's Management of Zhejiang Province Zhejiang University School of Medicine  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianbo","family":"Hu","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital Zhejiang University School of Medicine  Hangzhou China"},{"name":"The Key Laboratory of Mental Disorder's Management of Zhejiang Province  Hangzhou China"},{"name":"Department of Radiology, The First Affiliated Hospital, The Key Laboratory of Mental Disorder's Management of Zhejiang Province Zhejiang University 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