{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T15:54:01Z","timestamp":1781193241463,"version":"3.54.1"},"reference-count":55,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T00:00:00Z","timestamp":1502409600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007660","name":"Universiteit Antwerpen","doi-asserted-by":"publisher","award":["G815"],"award-info":[{"award-number":["G815"]}],"id":[{"id":"10.13039\/501100007660","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Patients with idiopathic adult\u2010onset cervical dystonia (<jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>) experience an abnormal head posture and involuntary muscle contractions. Although the exact areas affected in the central nervous system remain uncertain, impaired functions in systems stabilizing the head and neck are apparent such as the somatosensory and sensorimotor integration systems. The aim of the study is to investigate cervical sensorimotor control dysfunction in patients with <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>Cervical sensorimotor control was assessed by a head repositioning task in 24 patients with <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> and 70 asymptomatic controls. Blindfolded participants were asked to reposition their head to a previously memorized neutral head position (<jats:styled-content style=\"fixed-case\">NHP<\/jats:styled-content>) following an active movement (flexion, extension, left, and right rotation). The repositioning error (joint position error, <jats:styled-content style=\"fixed-case\">JPE<\/jats:styled-content>) was registered via 3D motion analysis with an eight\u2010camera infrared system (<jats:styled-content style=\"fixed-case\">VICON<\/jats:styled-content><jats:sup>\u00ae<\/jats:sup> T10). Disease\u2010specific characteristics of all patients were obtained via the Tsui scale, Cervical Dystonia Impact Profile (<jats:styled-content style=\"fixed-case\">CDIP<\/jats:styled-content>\u201058), and Toronto Western Spasmodic Rating Scale.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients with <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> showed larger <jats:styled-content style=\"fixed-case\">JPE<\/jats:styled-content> than controls (mean difference of 1.5\u00b0, <jats:italic>p\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>.006), and systematically \u2018overshoot\u2019, i.e. surpassed the <jats:styled-content style=\"fixed-case\">NHP<\/jats:styled-content>, whereas control subjects \u2018undershoot\u2019, i.e. fall behind the <jats:styled-content style=\"fixed-case\">NHP<\/jats:styled-content>. The <jats:styled-content style=\"fixed-case\">JPE<\/jats:styled-content> did not correlate with disease\u2010specific characteristics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Cervical sensorimotor control is impaired in patients with <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>. As cervical sensorimotor control can be trained, this might be a potential treatment option for therapy, adjuvant to botulinum toxin injections.<\/jats:p><\/jats:sec>","DOI":"10.1002\/brb3.735","type":"journal-article","created":{"date-parts":[[2017,8,12]],"date-time":"2017-08-12T04:10:41Z","timestamp":1502511041000},"source":"Crossref","is-referenced-by-count":18,"title":["Cervical sensorimotor control in idiopathic cervical dystonia: A\u00a0cross\u2010sectional study"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1798-4563","authenticated-orcid":false,"given":"Joke","family":"De Pauw","sequence":"first","affiliation":[{"name":"Department of Physical Therapy and Rehabilitation Sciences University of Antwerp  Wilrijk Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudy","family":"Mercelis","sequence":"additional","affiliation":[{"name":"Department of Neurology Antwerp University Hospital  Wilrijk Belgium"},{"name":"Faculty 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