{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T12:30:54Z","timestamp":1772022654521,"version":"3.50.1"},"reference-count":39,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,6,9]],"date-time":"2017-06-09T00:00:00Z","timestamp":1496966400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["16H03207"],"award-info":[{"award-number":["16H03207"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>This study aimed to clarify cortical circuit mechanisms contributing to corticomotor excitability during postexercise depression (<jats:styled-content style=\"fixed-case\">PED<\/jats:styled-content>) following repetitive nonfatiguing movement. We investigated changes in short\u2010latency afferent inhibition (<jats:styled-content style=\"fixed-case\">SAI<\/jats:styled-content>) and short\u2010interval intracortical inhibition (<jats:styled-content style=\"fixed-case\">SICI<\/jats:styled-content>) by paired\u2010pulse transcranial magnetic stimulation (<jats:styled-content style=\"fixed-case\">TMS<\/jats:styled-content>) during <jats:styled-content style=\"fixed-case\">PED<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 16 healthy subjects performed repetitive abduction movements of the right index finger at 2.0\u00a0Hz for 6\u00a0min at 10% maximum voluntary contraction. We measured <jats:styled-content style=\"fixed-case\">SAI<\/jats:styled-content> evoked by pairing ulnar nerve stimulation with <jats:styled-content style=\"fixed-case\">TMS<\/jats:styled-content> (interstimulus interval, 22\u00a0ms) before and during <jats:styled-content style=\"fixed-case\">PED<\/jats:styled-content> (<jats:italic>n<\/jats:italic>\u00a0=\u00a010, experiment 1). We also measured <jats:styled-content style=\"fixed-case\">SICI<\/jats:styled-content> evoked by paired <jats:styled-content style=\"fixed-case\">TMS<\/jats:styled-content> (interstimulus interval, 2\u00a0ms) at 80% resting motor threshold (<jats:italic>n<\/jats:italic>\u00a0=\u00a010, experiment 2), and at 80% active motor threshold (<jats:italic>n<\/jats:italic>\u00a0=\u00a08, experiment 3) before and during <jats:styled-content style=\"fixed-case\">PED<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Single motor evoked potential amplitude significantly decreased 1\u20132\u00a0min after the movement task in all experiments, indicating reliable <jats:styled-content style=\"fixed-case\">PED<\/jats:styled-content> induction. In experiment 1, <jats:styled-content style=\"fixed-case\">SAI<\/jats:styled-content> significantly decreased (disinhibited) 1\u20132\u00a0min during <jats:styled-content style=\"fixed-case\">PED<\/jats:styled-content>, whereas in experiments 2 and 3, <jats:styled-content style=\"fixed-case\">SICI<\/jats:styled-content> showed no significant change during <jats:styled-content style=\"fixed-case\">PED<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study suggests that cholinergic inhibitory circuit activity decreases during <jats:styled-content style=\"fixed-case\">PED<\/jats:styled-content> following repetitive nonfatiguing movement, whereas <jats:styled-content style=\"fixed-case\">GABA<jats:sub>A<\/jats:sub><\/jats:styled-content> circuit activity remains stable.<\/jats:p><\/jats:sec>","DOI":"10.1002\/brb3.744","type":"journal-article","created":{"date-parts":[[2017,6,9]],"date-time":"2017-06-09T08:07:51Z","timestamp":1496995671000},"source":"Crossref","is-referenced-by-count":13,"title":["Decrease in short\u2010latency afferent inhibition during corticomotor postexercise depression following repetitive finger movement"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1570-8891","authenticated-orcid":false,"given":"Shota","family":"Miyaguchi","sequence":"first","affiliation":[{"name":"Institute for Human Movement and Medical Sciences Niigata University of Health and Welfare  Niigata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sho","family":"Kojima","sequence":"additional","affiliation":[{"name":"Institute for Human Movement and Medical Sciences Niigata University of Health and Welfare  Niigata 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