{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T08:06:27Z","timestamp":1753862787887,"version":"3.41.2"},"reference-count":10,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,7,12]],"date-time":"2017-07-12T00:00:00Z","timestamp":1499817600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001823","name":"Ministerstvo \u0160kolstv\u00ed, Ml\u00e1de\u017ee a T\u011blov\u00fdchovy","doi-asserted-by":"publisher","award":["SVMUNI\/A\/1072\/2015"],"award-info":[{"award-number":["SVMUNI\/A\/1072\/2015"]}],"id":[{"id":"10.13039\/501100001823","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003243","name":"Ministerstvo Zdravotnictv\u00ed Cesk\u00e9 Republiky","doi-asserted-by":"publisher","award":["MH CZ \u2013 DRO, FNBr, 65269705"],"award-info":[{"award-number":["MH CZ \u2013 DRO, FNBr, 65269705"]}],"id":[{"id":"10.13039\/501100003243","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>A\u2010waves, which are observed following the M\u2010wave during motor nerve conduction studies (<jats:styled-content style=\"fixed-case\">NCS<\/jats:styled-content>), are late responses that are frequently found in many types of neurogenic disorders. However, A\u2010waves are also common in healthy individuals, where their significance remains unclear. The aim of this study was to examine whether the occurrence of A\u2010waves does in fact represent an increased risk for the future development of changes upon <jats:styled-content style=\"fixed-case\">NCS<\/jats:styled-content> or needle electromyography (<jats:styled-content style=\"fixed-case\">EMG<\/jats:styled-content>) in the corresponding nerve.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Nerve conduction studies\/needle electromyography findings at control examination were evaluated in relation to the occurrence of initial A\u2010waves in 327 individuals who had undergone repeated <jats:styled-content style=\"fixed-case\">NCS<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">EMG<\/jats:styled-content> examination and exhibited normal initial findings, with or without the occurrence of A\u2010waves as the only acceptable abnormality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The odds ratio, which reflects the predictive power of the occurrence of A\u2010waves at the initial testing for the development of an abnormality (neuropathy or radiculopathy) at the follow\u2010up examination, ranged from 2.7 (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.041) in the tibial nerve and 3.9 (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.034) in peroneal one, to 30.0 (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.002) in the ulnar nerve.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A\u2010waves constitute an initial abnormality in all nerves, and they may be predictive for the future development of broader <jats:styled-content style=\"fixed-case\">NCS<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">EMG<\/jats:styled-content> abnormalities in the corresponding nerve.<\/jats:p><\/jats:sec>","DOI":"10.1002\/brb3.760","type":"journal-article","created":{"date-parts":[[2017,7,13]],"date-time":"2017-07-13T10:35:03Z","timestamp":1499942103000},"source":"Crossref","is-referenced-by-count":5,"title":["A\u2010waves increase the risk of developing neuropathy"],"prefix":"10.1002","volume":"7","author":[{"given":"Iva","family":"Srotova","sequence":"first","affiliation":[{"name":"Department of Neurology Masaryk University and University Hospital Brno  Brno Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2322-5539","authenticated-orcid":false,"given":"Eva","family":"Vlckova","sequence":"additional","affiliation":[{"name":"Department of Neurology Masaryk University and University Hospital Brno  Brno Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ladislav","family":"Dusek","sequence":"additional","affiliation":[{"name":"Institute of Biostatistics and Analyses Masaryk University  Brno Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josef","family":"Bednarik","sequence":"additional","affiliation":[{"name":"Department of Neurology Masaryk University and University Hospital Brno  Brno Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,7,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(199710)20:10<1296::AID-MUS12>3.0.CO;2-1"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.10149"},{"key":"e_1_2_7_4_1","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/S0013-4694(96)96553-4","article-title":"Significance of A\u2010waves recorded in routine motor nerve conduction studies","volume":"101","author":"Bischoff C.","year":"1996","journal-title":"Electroencephalography and Clinical Neurophysiology"},{"volume-title":"Practical electromyography","year":"1994","author":"Kadanka Z.","key":"e_1_2_7_5_1"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/med\/9780199738687.001.0001"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(199903)22:3<394::AID-MUS13>3.0.CO;2-V"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0168-5597(92)90078-P"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.10448"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0168-5597(93)90104-W"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-4598(200007)23:7<1117::AID-MUS16>3.0.CO;2-#"}],"container-title":["Brain and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbrb3.760","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.760","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T05:34:46Z","timestamp":1696570486000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/brb3.760"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,12]]},"references-count":10,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["10.1002\/brb3.760"],"URL":"https:\/\/doi.org\/10.1002\/brb3.760","archive":["Portico"],"relation":{},"ISSN":["2162-3279","2162-3279"],"issn-type":[{"type":"print","value":"2162-3279"},{"type":"electronic","value":"2162-3279"}],"subject":[],"published":{"date-parts":[[2017,7,12]]},"article-number":"e00760"}}