{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T06:46:18Z","timestamp":1773297978281,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2017,10,12]],"date-time":"2017-10-12T00:00:00Z","timestamp":1507766400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Stroke Screening and Prevention Engineering Committee of People's Republic of China"},{"name":"Tianjin Health and Family Planning Commission science and technology foundation","award":["2015KZ022"],"award-info":[{"award-number":["2015KZ022"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2017,11]]},"abstract":"Abstract<\/jats:title>Introduction<\/jats:title>To analyze the risk factors of carotid plaque (CP<\/jats:styled-content>) and carotid common artery intima\u2010media thickening (CCAIMT<\/jats:styled-content>) and the association between the risk factors and CP<\/jats:styled-content> numbers and the side of the CCAIMT<\/jats:styled-content> in a high\u2010stroke\u2010risk population.<\/jats:p><\/jats:sec>Methods<\/jats:title>Carotid ultrasonography was conducted in 2025 participants with high stroke risk. Participants were divided into different groups according to the results of the ultrasound. The risk factors and blood biochemical indices were recorded.<\/jats:p><\/jats:sec>Results<\/jats:title>The presence of CP<\/jats:styled-content> and CCAIMT<\/jats:styled-content> were 38.9% and 24.8% respectively. Multivariate logistic regression indicated that the risk factors of CP<\/jats:styled-content> were age, high LDL<\/jats:styled-content>\u2010C and FBG<\/jats:styled-content> levels, male gender, stroke, diabetes, hypertension, and tobacco use. Compared with participants without CP<\/jats:styled-content>s, the participants who were male, and older in age, with risk factors of tobacco use, diabetes, high LDL<\/jats:styled-content>\u2010C levels, and a family history of hypertension were likely to have a single CP<\/jats:styled-content>, whereas the participants with risk factors of tobacco use, diabetes, hypertension, male gender, older age, high LDL<\/jats:styled-content>\u2010C levels, stroke and AF<\/jats:styled-content> or valvulopathy were prone to have multiple CP<\/jats:styled-content>s. The risk factors of CCAIMT<\/jats:styled-content> were male gender, stroke, hypertension, diabetes, AF<\/jats:styled-content> or valvulopathy, tobacco use and age. Compared with the N\u2010CCAIMT<\/jats:styled-content> subgroup, the risk factors of left CCAIMT<\/jats:styled-content> were tobacco use, diabetes, male gender, and age. The risk factors of right CCAIMT<\/jats:styled-content> were male gender, high FBG<\/jats:styled-content> levels, age, AF<\/jats:styled-content> or valvulopathy. The risk factors of dual CCAIMT<\/jats:styled-content> were high frequency of drinking milk, tobacco use, male gender, age, stroke, and hypertension.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>These findings revealed the risk factors of CP<\/jats:styled-content> and CCAIMT<\/jats:styled-content>, and an association between the risk factors and the CP<\/jats:styled-content> numbers and the side of the CCAIMT<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/brb3.847","type":"journal-article","created":{"date-parts":[[2017,10,12]],"date-time":"2017-10-12T10:22:39Z","timestamp":1507803759000},"source":"Crossref","is-referenced-by-count":20,"title":["Risk factors of carotid plaque and carotid common artery intima\u2010media thickening in a high\u2010stroke\u2010risk population"],"prefix":"10.1002","volume":"7","author":[{"given":"ChunFang","family":"Wang","sequence":"first","affiliation":[{"name":"First Central Clinical College of Tianjin Medical University Tianjin 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