{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:22:09Z","timestamp":1760955729227,"version":"3.41.2"},"reference-count":46,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2017,11,22]],"date-time":"2017-11-22T00:00:00Z","timestamp":1511308800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The implications of early readmission on long\u2010term mortality after transient ischemic attack (<jats:styled-content style=\"fixed-case\">TIA<\/jats:styled-content>) are not known. We aimed at examining the effect of 180\u2010day readmission on subsequent long\u2010term mortality after index hospitalization for <jats:styled-content style=\"fixed-case\">TIA<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study of patients hospitalized for first\u2010ever <jats:styled-content style=\"fixed-case\">TIA<\/jats:styled-content> at Mayo Clinic from 2000 through 2017. Patients readmitted within 180\u00a0days postdischarge were compared with those not readmitted in long\u2010term risk of death.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 251 <jats:styled-content style=\"fixed-case\">TIA<\/jats:styled-content> patients aged 73\u00a0\u00b1\u00a015\u00a0years with 1509 person\u2010years of follow\u2010up, 65 (26%) were readmitted within 180\u00a0days of discharge and 125 died during a median follow\u2010up of 5.7\u00a0years. The mortality was 10 vs. 7 deaths per 100 person\u2010years in patients who were readmitted compared to those who were not readmitted with hazard ratio (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>) 1.73 (95% confidence interval [<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>] 1.13\u20132.66). Other competing predictors of mortality were age \u226565\u00a0years (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> 5.70, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 2.72\u201311.96), cancer (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> 1.65, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.03\u20133.38), chronic obstructive pulmonary disease (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> 1.90, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.07\u20133.38), heart failure (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> 3.03, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.82\u20135.06), dementia (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> 5.87, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 3.27\u201310.52), creatinine \u22651.4\u00a0mg\/dl (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> 1.89, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.17\u20133.06), and hemoglobin level &lt;10\u00a0g\/dl (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> 2.80, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.20\u20136.66).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Hospital readmission within 180\u00a0days of discharge from index <jats:styled-content style=\"fixed-case\">TIA<\/jats:styled-content> was associated with increased risk of death several years after initial readmission. Older age and several comorbidities identified during index hospitalization also confer increased risk for long\u2010term mortality.<\/jats:p><\/jats:sec>","DOI":"10.1002\/brb3.865","type":"journal-article","created":{"date-parts":[[2017,11,22]],"date-time":"2017-11-22T05:16:47Z","timestamp":1511327807000},"source":"Crossref","is-referenced-by-count":6,"title":["Effect of early hospital readmission and comorbid conditions on subsequent long\u2010term mortality after transient ischemic attack"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7496-9856","authenticated-orcid":false,"given":"Mohammed","family":"Yousufuddin","sequence":"first","affiliation":[{"name":"Division of Hospital Medicine Mayo Clinic Health System  Austin MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan","family":"Young","sequence":"additional","affiliation":[{"name":"Division of Neurology Mayo Clinic  Rochester MN 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