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Previous studies have found category representations in prefrontal cortex and posterior parietal cortex (<jats:styled-content style=\"fixed-case\">PPC<\/jats:styled-content>). However, these higher\u2010order areas lack the fine\u2010scale spatial representations of early sensory areas, and it remains unclear what mechanisms enable flexible categorization based on fine\u2010scale features.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this study, we decoded functional <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> signals and measured causal influences, across visual, parietal, and prefrontal cortex from participants performing categorization based on coarse\u2010 or fine\u2010scale spatial information in thirteen healthy adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We show that category information based on coarse discriminations was represented in the <jats:styled-content style=\"fixed-case\">PPC<\/jats:styled-content>, in the intraparietal sulcus region, <jats:styled-content style=\"fixed-case\">IPS<\/jats:styled-content>1\/2, at an early stage of categorization trials, whereas representations of category information based on fine\u2010scale discriminations formed later during interactions between <jats:styled-content style=\"fixed-case\">IPS<\/jats:styled-content>1\/2 and primary visual cortex (V1). Specifically, when fine\u2010scale discriminations were necessary, we decoded significant category information from V1 at an intermediate stage of trials and again from <jats:styled-content style=\"fixed-case\">IPS<\/jats:styled-content>1\/2 at a late stage. <jats:styled-content style=\"fixed-case\">IPS<\/jats:styled-content>1\/2 feedback was critical, because categorization performance improved as causal influence from <jats:styled-content style=\"fixed-case\">IPS<\/jats:styled-content>1\/2 to V1 increased. Further, these mechanisms were plastic, as the selectivity of <jats:styled-content style=\"fixed-case\">IPS<\/jats:styled-content>1\/2 and V1 responses shifted markedly with retraining to categorize the same stimuli into two new groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our findings suggest that reentrant processing between the <jats:styled-content style=\"fixed-case\">PPC<\/jats:styled-content> and visual cortex enables flexible abstraction of category information.<\/jats:p><\/jats:sec>","DOI":"10.1002\/brb3.886","type":"journal-article","created":{"date-parts":[[2017,12,18]],"date-time":"2017-12-18T05:48:36Z","timestamp":1513576116000},"source":"Crossref","is-referenced-by-count":3,"title":["Feedback from human posterior parietal cortex enables visuospatial category representations as early as primary visual 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