{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:41:26Z","timestamp":1792629686005,"version":"4.5.0"},"reference-count":109,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T00:00:00Z","timestamp":1792540800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T00:00:00Z","timestamp":1792540800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Biological Reviews"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>In 2004, researchers found a population of mitotically active germ stem cells in adult mice capable of differentiating into oocyte\u2010like cells, which, by contradicting the long\u2010existing dogma on the non\u2010existence of postnatal oogenesis, caused a shift in fertility research. Further studies conducted in mice, human and other species have continuously confirmed the existence of these female germline stem cells.<\/jats:p>\n                  <jats:p>Given that these cells represent an extremely small portion of the total ovarian cell population, their isolation has been exceptionally challenging, with some studies being unable to identify these cells. Moreover, studies that identified these stem cells have observed a variety of sizes, morphologies and expression profiles.<\/jats:p>\n                  <jats:p>Thus, there is a lack of consensus on the characteristics of female germline stem cells, including their terminology, as different researchers have called them \u2018female germline stem cells\u2019, \u2018oogonial stem cells\u2019, \u2018egg precursor cells\u2019, \u2018very small embryonic\u2010like stem cells\u2019 or other terms. This review summarises the findings on these stem cells from the ovaries of a range of species, with the aim of proposing a standardised terminology based on their intrinsic characteristics. We hope that this terminology will be unanimously used in future fertility studies.<\/jats:p>","DOI":"10.1002\/brv.70214","type":"journal-article","created":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T23:50:46Z","timestamp":1792626646000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Categorisation of female germline stem cells based on their morphology and marker expression profiles"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7019-0186","authenticated-orcid":false,"given":"Rita L.","family":"Sousa","sequence":"first","affiliation":[{"name":"Gamete Research Centre, Veterinary Physiology and Biochemistry, Department of Veterinary Sciences University of Antwerp  Wilrijk Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecibel M.","family":"Le\u00f3n\u2010F\u00e9lix","sequence":"additional","affiliation":[{"name":"Gamete Research Centre, Veterinary Physiology and Biochemistry, Department of Veterinary Sciences University of Antwerp  Wilrijk Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0432-8719","authenticated-orcid":false,"given":"Peter E. J.","family":"Bols","sequence":"additional","affiliation":[{"name":"Gamete Research Centre, Veterinary Physiology and Biochemistry, Department of Veterinary Sciences University of Antwerp  Wilrijk Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0170-1963","authenticated-orcid":false,"given":"Ruth","family":"Appeltant","sequence":"additional","affiliation":[{"name":"Gamete Research Centre, Veterinary Physiology and Biochemistry, Department of Veterinary Sciences University of Antwerp  Wilrijk Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,21]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/j.1365-2443.2010.01400.x","article-title":"Role of SOX2 in maintaining pluripotency of human embryonic stem cells","volume":"15","author":"Adachi K.","year":"2010","journal-title":"Genes to Cells"},{"key":"e_1_2_12_3_1","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1093\/stmcls\/sxac015","article-title":"Workflow optimization for identification of female germline or oogonial stem cells in human ovarian cortex using single\u2010cell RNA sequence analysis","volume":"40","author":"Alberico H.","year":"2022","journal-title":"Stem Cells"},{"key":"e_1_2_12_4_1","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1007\/BF01306883","article-title":"Regenerative capacity of rat ovary after compensatory hypertrophy","volume":"51","author":"Artem'eva N. 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