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To inform this issue, the Health Policy Professional Interest Area of the International Society to Advance Alzheimer's Research and Treatment convened an expert discussion with researchers, clinicians, policymakers, and advocates, identifying three recurring challenges: difficulties translating research into actionable guidance, limited evaluation of real\u2011world impact, and persistent inequities in access to dementia care. Building on these insights, this narrative review applies the Evidence\u2011Informed Policy and Practice framework to examine how evidence is sourced, interpreted, and implemented across diverse settings. Integrating peer\u2011reviewed literature, policy documents, and practice\u2011based insights, the review highlights structural and institutional determinants of evidence generation, the contextual factors shaping evidence use, and system\u2011level constraints and enabling mechanisms influencing implementation. 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