{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:35:08Z","timestamp":1786977308820,"version":"build-2736575974"},"reference-count":138,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T00:00:00Z","timestamp":1652659200000},"content-version":"vor","delay-in-days":76,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Behavioral Sci &amp; The Law"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Individuals with borderline personality disorder (BPD) or antisocial personality disorder (ASPD) are overrepresented in forensic settings. Yet, despite the burden these disorders place on healthcare and criminal justice systems, there remains a lack of evidence\u2010based pharmacological treatments. Epidemiological data have shown that comorbid cannabis use disorders are common in BPD and ASPD. \u2206\n                    <jats:sup>9<\/jats:sup>\n                    \u2010Tetrahydrocannabinol, the primary psychoactive constituent of cannabis, is an exogenous cannabinoid that stimulates the endocannabinoid system (ECS). Hence, an investigation of the ECS in these conditions is warranted. This scoping review screened 105 records and summarized the extant research on the ECS in ASPD (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a069) and BPD (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a061) participants. Preliminary results suggest that alterations of the ECS may be present in these disorders. Although research examining the ECS in personality disorders is still in its infancy, more research is warranted given initial positive findings.\n                  <\/jats:p>","DOI":"10.1002\/bsl.2576","type":"journal-article","created":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T06:31:44Z","timestamp":1652682704000},"page":"331-350","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["The endocannabinoid system in borderline personality disorder and antisocial personality disorder: A scoping review"],"prefix":"10.1002","volume":"40","author":[{"given":"Wilson","family":"Ho","sequence":"first","affiliation":[{"name":"Faculty of Medicine University of Toronto  Toronto ON Canada"},{"name":"Brain Health Imaging Centre Centre for Addiction and Mental Health  Toronto ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan J.","family":"Kolla","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Toronto  Toronto ON Canada"},{"name":"Brain Health Imaging Centre Centre for Addiction and Mental Health  Toronto ON Canada"},{"name":"Department of Psychiatry University of Toronto  Toronto ON Canada"},{"name":"Waypoint Centre for Mental Health Care  Penetanguishene ON Canada"},{"name":"Waypoint\/University of Toronto Research Chair in Forensic Mental Health Science  Penetanguishene ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00406\u2010016\u20100760\u2010z"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.2174\/157015907780866910"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0028\u20103932(00)00136\u20106"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398\u2010018\u20100141\u20107"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.2165\/00023210\u2010200822080\u201000005"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2016.07.024"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41386\u2010020\u20100606\u20102"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/09585189008408453"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.comppsych.2007.04.006"},{"issue":"2","key":"e_1_2_6_12_1","first-page":"113","article-title":"Antisocial personality disorder in incarcerated offenders: Psychiatric comorbidity and quality of life","volume":"22","author":"Black D. W.","year":"2010","journal-title":"Annals of Clinical Psychiatry"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1124\/pr.112.006387"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2016.04.012"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2015.133"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2015.119"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000031422.66442.49"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2019.1427"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2006.12.001"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2013.06.009"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2012.210"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0014\u20102999(97)01255\u20107"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2013.06.002"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.4088\/jcp.v68n0217"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ynstr.2021.100337"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2021.01.021"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddh216"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2008.07.018"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2006.08.024"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.189.1.12"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.4088\/jcp.v66n0602"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213\u2010019\u201005289\u2010x"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213\u2010018\u20105020\u20107"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1521\/pedi.15.2.180.19212"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1521\/pedi.2000.14.2.162"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398\u2010021\u201001446\u2010z"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2553"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms7395"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215\u20100366(18)30427\u20109"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.4088\/jcp.v65n0302"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1037\/lhb0000105"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.12.033"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/0010\u2010440x(70)90202\u20106"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(02)07740\u20101"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2021.744061"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2018.02.004"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0605493103"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213\u2010009\u20101569\u20105"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.comppsych.2014.09.001"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00004.2003"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40263\u2010021\u201000855\u20104"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007668.pub3"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.14209"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0306\u20104522(96)00428\u20109"},{"key":"e_1_2_6_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11920\u2010011\u20100249\u20104"},{"key":"e_1_2_6_56_1","doi-asserted-by":"publisher","DOI":"10.1093\/ijnp\/pyu104"},{"key":"e_1_2_6_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0193\u2010953x(05)70141\u20106"},{"key":"e_1_2_6_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2008.10.047"},{"key":"e_1_2_6_59_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.87.5.1932"},{"key":"e_1_2_6_60_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471\u20104159.2008.05567.x"},{"key":"e_1_2_6_61_1","doi-asserted-by":"publisher","DOI":"10.2174\/187152709789824624"},{"key":"e_1_2_6_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2018.07.009"},{"key":"e_1_2_6_63_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1996.01830060031004"},{"key":"e_1_2_6_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03033482"},{"key":"e_1_2_6_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447\u20100349.2007.00508.x"},{"key":"e_1_2_6_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2006.12.023"},{"key":"e_1_2_6_67_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1996.01830060057008"},{"key":"e_1_2_6_68_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2009.19"},{"key":"e_1_2_6_69_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00019.2008"},{"key":"e_1_2_6_70_1","doi-asserted-by":"publisher","DOI":"10.1080\/1068316X.2015.1077250"},{"key":"e_1_2_6_71_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2016.00294"},{"key":"e_1_2_6_72_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007667.pub3"},{"key":"e_1_2_6_73_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010022\u201004789\u20109"},{"key":"e_1_2_6_74_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398\u2010020\u201001144\u20102"},{"key":"e_1_2_6_75_1","doi-asserted-by":"publisher","DOI":"10.1080\/13811110701542010"},{"key":"e_1_2_6_76_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnbeh.2018.00041"},{"key":"e_1_2_6_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41386\u2010020\u20100731\u2010y"},{"key":"e_1_2_6_78_1","doi-asserted-by":"publisher","DOI":"10.1185\/030079908x280707"},{"key":"e_1_2_6_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2009.07.014"},{"key":"e_1_2_6_80_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2008.46"},{"key":"e_1_2_6_81_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000100"},{"key":"e_1_2_6_82_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.108.062984"},{"key":"e_1_2_6_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1077\u20107229(00)80056\u20105"},{"key":"e_1_2_6_84_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1991.01810360024003"},{"key":"e_1_2_6_85_1","doi-asserted-by":"publisher","DOI":"10.1521\/pedi.2010.24.5.610"},{"key":"e_1_2_6_86_1","doi-asserted-by":"publisher","DOI":"10.3109\/15622975.2016.1151075"},{"issue":"3","key":"e_1_2_6_87_1","first-page":"498","article-title":"Anandamide, an endogenous cannabinoid, inhibits calcium currents as a partial agonist in N18 neuroblastoma cells","volume":"44","author":"Mackie K.","year":"1993","journal-title":"Molecular Pharmacology"},{"key":"e_1_2_6_88_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291709990729"},{"key":"e_1_2_6_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2019.07.034"},{"key":"e_1_2_6_90_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.108.138321"},{"key":"e_1_2_6_91_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022\u2010006x.71.2.320"},{"key":"e_1_2_6_92_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0171592"},{"key":"e_1_2_6_93_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00702\u2010008\u20100076\u2010x"},{"key":"e_1_2_6_94_1","doi-asserted-by":"publisher","DOI":"10.1111\/1556\u20104029.15000"},{"key":"e_1_2_6_95_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2020.00315"},{"key":"e_1_2_6_96_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2174"},{"key":"e_1_2_6_97_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1301283"},{"key":"e_1_2_6_98_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpm.12116"},{"key":"e_1_2_6_99_1","doi-asserted-by":"publisher","DOI":"10.1037\/prj0000088"},{"key":"e_1_2_6_100_1","doi-asserted-by":"publisher","DOI":"10.1177\/2040622310368455"},{"key":"e_1_2_6_101_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2013.74"},{"key":"e_1_2_6_102_1","doi-asserted-by":"publisher","DOI":"10.1177\/1039856218810154"},{"key":"e_1_2_6_103_1","doi-asserted-by":"publisher","DOI":"10.1177\/1049731513503047"},{"key":"e_1_2_6_104_1","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2012.1"},{"key":"e_1_2_6_105_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11920\u2010009\u20100083\u20100"},{"key":"e_1_2_6_106_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5603\u201007.2008"},{"key":"e_1_2_6_107_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1527\u20103458.2006.00021.x"},{"key":"e_1_2_6_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2010.02.015"},{"key":"e_1_2_6_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pscychresns.2013.06.006"},{"key":"e_1_2_6_110_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1990.03450190043026"},{"key":"e_1_2_6_111_1","doi-asserted-by":"publisher","DOI":"10.1080\/00332747.1991.11024540"},{"issue":"10","key":"e_1_2_6_112_1","first-page":"16","article-title":"Borderline personality and criminality","volume":"6","author":"Sansone R. A.","year":"2009","journal-title":"Psychiatry"},{"key":"e_1_2_6_113_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00406\u2010013\u20100470\u20108"},{"key":"e_1_2_6_114_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41386\u2010020\u201000888\u20101"},{"key":"e_1_2_6_115_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpsc.2016.07.003"},{"key":"e_1_2_6_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chiabu.2020.104621"},{"key":"e_1_2_6_117_1","doi-asserted-by":"publisher","DOI":"10.1177\/0306624X16653193"},{"key":"e_1_2_6_118_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11682\u2010018\u20109945\u20106"},{"key":"e_1_2_6_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0193\u2010953X(05)70143\u2010X"},{"key":"e_1_2_6_120_1","doi-asserted-by":"publisher","DOI":"10.1615\/critrevneurobiol.v15.i2.10"},{"key":"e_1_2_6_121_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.082235799"},{"key":"e_1_2_6_122_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0006\u20103223(02)01325\u20102"},{"key":"e_1_2_6_123_1","doi-asserted-by":"publisher","DOI":"10.1023\/a:1025730901955"},{"key":"e_1_2_6_124_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.9.1123"},{"key":"e_1_2_6_125_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001756\u2010200312020\u201000015"},{"key":"e_1_2_6_126_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012955.pub2"},{"key":"e_1_2_6_127_1","doi-asserted-by":"publisher","DOI":"10.1037\/1064\u20101297.12.1.65"},{"key":"e_1_2_6_128_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476\u20105381.2010.00790.x"},{"key":"e_1_2_6_129_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12671\u2010018\u20101048\u20103"},{"key":"e_1_2_6_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2017.04.005"},{"key":"e_1_2_6_131_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306\u20104522(94)90511\u20108"},{"key":"e_1_2_6_132_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2016.02.010"},{"key":"e_1_2_6_133_1","doi-asserted-by":"publisher","DOI":"10.1080\/10253890.2018.1451837"},{"key":"e_1_2_6_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2010.04.034"},{"key":"e_1_2_6_135_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00127\u2010007\u20100226\u20108"},{"key":"e_1_2_6_136_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pscychresns.2009.03.012"},{"key":"e_1_2_6_137_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11920\u2010004\u20100041\u20109"},{"key":"e_1_2_6_138_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.201400055"},{"key":"e_1_2_6_139_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19030833"}],"container-title":["Behavioral Sciences &amp; the Law"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bsl.2576","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/bsl.2576","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bsl.2576","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T00:11:07Z","timestamp":1692835867000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bsl.2576"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":138,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["10.1002\/bsl.2576"],"URL":"https:\/\/doi.org\/10.1002\/bsl.2576","archive":["Portico"],"relation":{},"ISSN":["0735-3936","1099-0798"],"issn-type":[{"value":"0735-3936","type":"print"},{"value":"1099-0798","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"2021-11-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-31","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}