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It is unlikely that delusional disorder is strongly related genetically to affective disorder or schizophrenia, but more subtle relationships cannot be ruled out. The rarity of multiply affected families prohibits linkage studies and, to date, molecular genetic investigations have been mainly limited to small association studies of dopamine receptor polymorphisms. A range of considerably larger, epidemiologically rigorous studies is required, but the uncommonness and other features of the disorder put strong limitations on the prospects for ascertaining adequate samples. Copyright \u00a9 2006 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/bsl.681","type":"journal-article","created":{"date-parts":[[2006,5,16]],"date-time":"2006-05-16T17:25:40Z","timestamp":1147800340000},"page":"257-276","source":"Crossref","is-referenced-by-count":16,"title":["Genetics and delusional disorder"],"prefix":"10.1002","volume":"24","author":[{"given":"Alastair G.","family":"Cardno","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"McGuffin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,5,16]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.186.2.91"},{"key":"e_1_2_1_3_1","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"1980"},{"key":"e_1_2_1_4_1","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"1987"},{"key":"e_1_2_1_5_1","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"1994"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1964.tb05758.x"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.56.2.162"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3223(93)90236-7"},{"key":"e_1_2_1_9_1","unstructured":"Debray Q.(1974).Etude genetique des delires chroniques. 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