{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T05:26:59Z","timestamp":1790573219903,"version":"4.1.0"},"reference-count":145,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T00:00:00Z","timestamp":1652745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2019CXTD03"],"award-info":[{"award-number":["2019CXTD03"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2019GGRC03"],"award-info":[{"award-number":["2019GGRC03"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2020\u2010JCJQ\u2010JJ\u2010358"],"award-info":[{"award-number":["2020\u2010JCJQ\u2010JJ\u2010358"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aiche.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Bioengineering &amp;amp; Transla Med"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Fatigue causes deleterious effects to physical and mental health of human being and may cause loss of lives. Therefore, the adverse effects of fatigue on individuals and the society are massive. With the ever\u2010increasing frequency of overtraining among modern military and sports personnel, timely, portable and accurate fatigue diagnosis is essential to avoid fatigue\u2010induced accidents. However, traditional detection methods require complex sample preparation and blood sampling processes, which cannot meet the timeliness and portability of fatigue diagnosis. With the development of flexible materials and biosensing technology, wearable biosensors have attracted increased attention to the researchers. Wearable biosensors collect biomarkers from noninvasive biofluids, such as sweat, saliva, and tears, followed by biosensing with the help of biosensing modules continuously and quantitatively. The detection signal can then be transmitted through wireless communication modules that constitute a method for real\u2010time understanding of abnormality. Recent developments of wearable biosensors are focused on miniaturized wearable electrochemistry and optical biosensors for metabolites detection, of which, few have exhibited satisfactory results in medical diagnosis. However, detection performance limits the wide\u2010range applicability of wearable fatigue diagnosis. In this article, the application of wearable biosensors in fatigue diagnosis has been discussed. In fact, exploration of the composition of different biofluids and their potential toward fatigue diagnosis have been discussed here for the very first time. Moreover, discussions regarding the current bottlenecks in wearable fatigue biosensors and the latest advancements in biochemical reaction and data communication modules have been incorporated herein. Finally, the main challenges and opportunities were discussed for wearable fatigue diagnosis in the future.<\/jats:p>","DOI":"10.1002\/btm2.10318","type":"journal-article","created":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T05:55:10Z","timestamp":1652766910000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Wearable biosensors for human fatigue diagnosis: A review"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3078-6900","authenticated-orcid":false,"given":"Jingyang","family":"Zhang","sequence":"first","affiliation":[{"name":"Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety Institute of Environmental and Operational Medicine  Tianjin P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengmeng","family":"Chen","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety Institute of Environmental and Operational Medicine  Tianjin P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Peng","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety Institute of Environmental and Operational Medicine  Tianjin P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuang","family":"Li","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety Institute of Environmental and Operational Medicine  Tianjin P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dianpeng","family":"Han","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety Institute of Environmental and Operational Medicine  Tianjin P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuyue","family":"Ren","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety Institute of Environmental and Operational Medicine  Tianjin P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kang","family":"Qin","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety Institute of Environmental and Operational Medicine  Tianjin P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sen","family":"Li","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety Institute of Environmental and Operational Medicine  Tianjin P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tie","family":"Han","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety Institute of Environmental and Operational Medicine  Tianjin P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Wang","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety Institute of Environmental and Operational Medicine  Tianjin P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhixian","family":"Gao","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety Institute of Environmental and Operational Medicine  Tianjin P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,17]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000006075"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsr.2016.11.006"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsr.2019.12.015"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/bmb\/ldm014"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/occmed\/kqy109"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annrmp.2006.04.007"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7CS00730B"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00420-020-01641-3"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1123\/ijspp.2020-0933"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00892.2020"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-019-04162-1"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2020.11235"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1365\/s10337-004-0412-8"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2019.111695"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.287"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2020.01037"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/bios11060190"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2016.11.067"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjms.2019.12.012"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/s21124174"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12928-021-00788-1"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.3390\/s21103461"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajh\/hpaa158"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201900109"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.07.019"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2019.111422"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.3390\/electronics10050608"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2020.108053"},{"issue":"4","key":"e_1_2_10_30_1","first-page":"2327","article-title":"Accurate monitoring of parkinson's disease symptoms with a wearable device during COVID\u201019 pandemic","volume":"35","author":"Tsamis KI","year":"2021","journal-title":"In Vivo (Athens, Greece)"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c07614"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2021.105367"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(21)02573-7"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-92430-6"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keaa115"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2010.07.060"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2008.11.018"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.1c04139"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2022.123338"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2019.04.061"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6528\/abce2d"},{"issue":"4","key":"e_1_2_10_42_1","first-page":"206","article-title":"An HPLC\u2010DAD validated method for the detection and quantification of cortisol, corticosterone and melatonin in plasma samples of two different animal species","volume":"74","author":"Viljoen FP","year":"2019","journal-title":"Pharmazie"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.3390\/bios11090304"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1TB02550C"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-018-0939-4"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2017.06.030"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-019-1961-4"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-019-0045-y"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.3390\/bios10080086"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.4103\/jfmpc.jfmpc_138_20"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.imbio.2019.04.001"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejcn.2017.136"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-24543-4"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40279-017-0691-5"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2018.09.086"},{"issue":"3","key":"e_1_2_10_56_1","first-page":"109","article-title":"Uric acid and urea in human sweat","volume":"45","author":"Huang CT","year":"2002","journal-title":"Chin J Physiol"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-75871-3"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2015-095113"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5AN00464K"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2020.8799"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2021.733810"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1109\/JSEN.2020.2969635"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2020.112483"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1021\/acssensors.6b00356"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aar2904"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2019.111637"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2020.112133"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2012700117"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abe4553"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1177\/2472630318759257"},{"key":"e_1_2_10_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2020.121145"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.9b03110"},{"key":"e_1_2_10_73_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.8b04877"},{"key":"e_1_2_10_74_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-021-00685-1"},{"key":"e_1_2_10_75_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201800880"},{"key":"e_1_2_10_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compscitech.2021.108894"},{"key":"e_1_2_10_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2020.111298"},{"key":"e_1_2_10_78_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202008479"},{"key":"e_1_2_10_79_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9AN01679A"},{"key":"e_1_2_10_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2015.07.039"},{"key":"e_1_2_10_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2015.12.014"},{"key":"e_1_2_10_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2019.04.058"},{"key":"e_1_2_10_83_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms14997"},{"key":"e_1_2_10_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2006.05.006"},{"key":"e_1_2_10_85_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-019-01788-0"},{"key":"e_1_2_10_86_1","doi-asserted-by":"publisher","DOI":"10.1039\/C3AN02359A"},{"key":"e_1_2_10_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0956-5663(01)00189-0"},{"key":"e_1_2_10_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2010.10.055"},{"key":"e_1_2_10_89_1","doi-asserted-by":"publisher","DOI":"10.1109\/JSSC.2011.2170633"},{"key":"e_1_2_10_90_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.9b03379"},{"issue":"1","key":"e_1_2_10_91_1","first-page":"87","article-title":"A comparative study of serum, urine and saliva using rk39 strip for the diagnosis of visceral leishmaniasis","volume":"10","author":"Mohapatra S","year":"2016","journal-title":"J Arthropod Borne Dis"},{"issue":"3","key":"e_1_2_10_92_1","first-page":"307","article-title":"Alcohol saliva strip test","volume":"8","author":"Thokala MR","year":"2014","journal-title":"J Clin Diagn Res"},{"key":"e_1_2_10_93_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201703257"},{"key":"e_1_2_10_94_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-19239-8"},{"key":"e_1_2_10_95_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/41.10.1522"},{"key":"e_1_2_10_96_1","doi-asserted-by":"publisher","DOI":"10.3390\/s18051431"},{"issue":"3","key":"e_1_2_10_97_1","doi-asserted-by":"crossref","first-page":"94A","DOI":"10.1016\/S0002-9149(97)00463-3","article-title":"Myocardial blood flow and glucose metabolism in diabetes mellitus","volume":"80","author":"Christian M","year":"1997","journal-title":"Am J Cardiol"},{"key":"e_1_2_10_98_1","doi-asserted-by":"publisher","DOI":"10.1080\/00325481.2016.1221732"},{"issue":"15","key":"e_1_2_10_99_1","first-page":"4137","article-title":"High serum cortisol levels are associated with fatigue and verbal fluency in Parkinson's disease: preliminary results","volume":"94","author":"Magalhaes PG","year":"2020","journal-title":"Neurology"},{"key":"e_1_2_10_100_1","doi-asserted-by":"publisher","DOI":"10.1080\/17461391.2018.1480661"},{"key":"e_1_2_10_101_1","doi-asserted-by":"publisher","DOI":"10.1139\/H08-085"},{"key":"e_1_2_10_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2015.12.055"},{"key":"e_1_2_10_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2008.09.026"},{"key":"e_1_2_10_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2019.113533"},{"key":"e_1_2_10_105_1","doi-asserted-by":"publisher","DOI":"10.3390\/bios9010046"},{"key":"e_1_2_10_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2005.07.012"},{"key":"e_1_2_10_107_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408347.2018.1461552"},{"key":"e_1_2_10_108_1","doi-asserted-by":"publisher","DOI":"10.1590\/0001-3765201820170514"},{"key":"e_1_2_10_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-2670(00)83828-3"},{"key":"e_1_2_10_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2004.12.001"},{"key":"e_1_2_10_111_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac401573r"},{"key":"e_1_2_10_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2019.01.002"},{"key":"e_1_2_10_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2015.02.059"},{"key":"e_1_2_10_114_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-018-2545-6"},{"key":"e_1_2_10_115_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201700102"},{"key":"e_1_2_10_116_1","doi-asserted-by":"publisher","DOI":"10.3390\/bios10040040"},{"key":"e_1_2_10_117_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-020-03002-y"},{"key":"e_1_2_10_118_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-02133-0"},{"key":"e_1_2_10_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2020.112782"},{"key":"e_1_2_10_120_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202008465"},{"key":"e_1_2_10_121_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics13060774"},{"key":"e_1_2_10_122_1","doi-asserted-by":"publisher","DOI":"10.1080\/07388551.2021.1874281"},{"key":"e_1_2_10_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.marpolbul.2021.112541"},{"key":"e_1_2_10_124_1","doi-asserted-by":"publisher","DOI":"10.3390\/polym13040548"},{"key":"e_1_2_10_125_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2020.04.022"},{"key":"e_1_2_10_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2021.122274"},{"key":"e_1_2_10_127_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202008231"},{"key":"e_1_2_10_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2017.12.021"},{"key":"e_1_2_10_129_1","doi-asserted-by":"publisher","DOI":"10.3390\/mi11100895"},{"key":"e_1_2_10_130_1","doi-asserted-by":"publisher","DOI":"10.3390\/s20216289"},{"key":"e_1_2_10_131_1","doi-asserted-by":"publisher","DOI":"10.3390\/bios10120209"},{"key":"e_1_2_10_132_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aaf2593"},{"key":"e_1_2_10_133_1","doi-asserted-by":"publisher","DOI":"10.1039\/C8LC00530C"},{"key":"e_1_2_10_134_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.5b05001"},{"key":"e_1_2_10_135_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2009.02.032"},{"key":"e_1_2_10_136_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2015.08.073"},{"key":"e_1_2_10_137_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2012.06.048"},{"key":"e_1_2_10_138_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.9b04927"},{"key":"e_1_2_10_139_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201703334"},{"key":"e_1_2_10_140_1","doi-asserted-by":"publisher","DOI":"10.3390\/s20051381"},{"key":"e_1_2_10_141_1","doi-asserted-by":"publisher","DOI":"10.1049\/iet-map.2019.0451"},{"key":"e_1_2_10_142_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.7b04753"},{"key":"e_1_2_10_143_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2020.111345"},{"key":"e_1_2_10_144_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrep.2015.11.010"},{"key":"e_1_2_10_145_1","doi-asserted-by":"publisher","DOI":"10.1111\/gcb.14883"},{"key":"e_1_2_10_146_1","doi-asserted-by":"publisher","DOI":"10.2175\/106143015X14338845155985"}],"container-title":["Bioengineering &amp; Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/btm2.10318","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/btm2.10318","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aiche.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/btm2.10318","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T22:10:24Z","timestamp":1760047824000},"score":1,"resource":{"primary":{"URL":"https:\/\/aiche.onlinelibrary.wiley.com\/doi\/10.1002\/btm2.10318"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,17]]},"references-count":145,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["10.1002\/btm2.10318"],"URL":"https:\/\/doi.org\/10.1002\/btm2.10318","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1002\/BTM2.10318\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BTM2.10318\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BTM2.10318\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BTM2.10318\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BTM2.10318\/v1\/review2","asserted-by":"object"}]},"ISSN":["2380-6761","2380-6761"],"issn-type":[{"value":"2380-6761","type":"print"},{"value":"2380-6761","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,17]]},"assertion":[{"value":"2022-02-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e10318"}}