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Herein, we report a soft, wearable and battery\u2010free wound dressing system (WDS) for wireless and real\u2010time monitoring of wound condition and sepsis\u2010related biomarker (procalcitonin [PCT]) in wound exudate for early sepsis detection. The battery\u2010free WDS powered by near\u2010field communication enables wireless data transmission, signal processing and power supply, which allows portable intelligent wound caring. The exudate collection associates with soft silicone based microfluidic technologies (exudate collection time within 15\u2009s), that can filtrate contamination at the cell level and enable a superior filtration rate up to 95% with adopting microsphere structures. The battery\u2010free WDS also includes state\u2010of\u2010the\u2010art biosensors, which can accurate detect the pH value, wound temperature, and PCT level and thus for sepsis diagnosis. In vivo studies of SD rats prove the capability of the WDS for continuously monitoring wound condition and PCT concentration in the exudate. As a result, the reported fully integrated WDS provides a potential solution for further developing wearable, multifunctional and on\u2010site disease diagnosis.<\/jats:p>","DOI":"10.1002\/btm2.10445","type":"journal-article","created":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T05:43:47Z","timestamp":1675230227000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Wearable and battery\u2010free wound dressing system for wireless and early sepsis diagnosis"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4726-4559","authenticated-orcid":false,"given":"Jiyu","family":"Li","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering City University of Hong Kong  Kowloon Tong Hong Kong"},{"name":"Hong Kong Center for Cerebra\u2010Cardiovascular Health Engineering Hong Kong Science Park  New Territories Hong 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