{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T17:30:30Z","timestamp":1775928630923,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,7,19]],"date-time":"2023-07-19T00:00:00Z","timestamp":1689724800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,7,19]],"date-time":"2023-07-19T00:00:00Z","timestamp":1689724800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["S10RR029020\u201001"],"award-info":[{"award-number":["S10RR029020\u201001"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["ECCS\u20102026822"],"award-info":[{"award-number":["ECCS\u20102026822"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aiche.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Bioengineering &amp;amp; Transla Med"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Cardiac electrophysiology mapping and ablation are widely used to treat heart rhythm disorders such as atrial fibrillation (AF) and ventricular tachycardia (VT). Here, we describe an approach for rapid production of three dimensional (3D)\u2010printed mapping devices derived from magnetic resonance imaging. The mapping devices are equipped with flexible electronic arrays that are shaped to match the epicardial contours of the atria and ventricle and allow for epicardial electrical mapping procedures. We validate that these flexible arrays provide high\u2010resolution mapping of epicardial signals in vivo using porcine models of AF and myocardial infarction. Specifically, global coverage of the epicardial surface allows for mapping and ablation of myocardial substrate and the capture of premature ventricular complexes with precise spatial\u2013temporal resolution. We further show, as proof\u2010of\u2010concept, the localization of sites of VT by means of beat\u2010to\u2010beat whole\u2010chamber ventricular mapping of ex vivo Langendorff\u2010perfused human hearts.<\/jats:p>","DOI":"10.1002\/btm2.10575","type":"journal-article","created":{"date-parts":[[2023,7,20]],"date-time":"2023-07-20T01:42:55Z","timestamp":1689817375000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Electrophysiological mapping of the epicardium via\n                    <scp>3D<\/scp>\n                    \u2010printed flexible arrays"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4382-9890","authenticated-orcid":false,"given":"Terrence","family":"Pong","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery School of Medicine, Stanford University  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin J.","family":"Cyr","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery School of Medicine, Stanford University  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cody","family":"Carlton","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery School of Medicine, Stanford University  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joy","family":"Aparicio\u2010Valenzuela","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery School of Medicine, Stanford University  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanjay","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery School of Medicine, Stanford University  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meghedi","family":"Babakhanian","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine School of Medicine, Stanford University  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Maiuolo","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery School of Medicine, Stanford University  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haley","family":"Lucian","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery School of Medicine, Stanford University  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul J.","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine School of Medicine, Stanford University  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y. Joseph","family":"Woo","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery School of Medicine, Stanford University  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anson M.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery School of Medicine, Stanford University  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,7,19]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-017-0180-z"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aav9051"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semtcvs.2022.03.003"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2014.118"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2010.01887.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2007.00956.x"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.109.859116"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMct1109977"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.111.963413"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.117.005748"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.113.000342"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2018.10.010"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/joa3.12308"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.01.016"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/imi.0b013e318248f3f4"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmat2971"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms4329"},{"key":"e_1_2_10_19_1","first-page":"1","article-title":"Capacitively coupled arrays of multiplexed flexible silicon transistors for long\u2010term cardiac electrophysiology","volume":"1","author":"Fang H","year":"2017","journal-title":"Nat Biomed Eng"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature25494"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2000207117"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.829546"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2006.01.015"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/ahe.12099"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000147781.02738.13"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.910901"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.117.005858"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2009.232"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/imi.0000000000000230"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0271846"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.11.054"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.12.054"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.2174\/157340312803217229"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.517011"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0709758104"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.1999.1766"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2016.05.026"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-25861-3"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(90)92832-M"},{"key":"e_1_2_10_40_1","article-title":"Optocardiography and electrophysiology studies of ex vivo Langendorff\u2010perfused hearts","volume":"153","author":"Swift LM","year":"2019","journal-title":"J Vis Exp"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1006\/phrs.1999.0653"}],"container-title":["Bioengineering &amp; 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