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The CAR enables the T cells to bind and eradicate cells with a specific surface marker (e.g., CD19\n                    <jats:sup>+<\/jats:sup>\n                    B cells) after they are transfused back into the patient. This treatment was proven to be particularly effective in treating non\u2010Hodgkin's lymphoma (NHL) and acute lymphoblastic leukemia (ALL), but the current CAR\u2010T cell manufacturing process has a few significant drawbacks. For example, while lentiviral and gammaretroviral transduction are both relatively effective, the process of producing viral vectors is time\u2010consuming and costly. Additionally, patients must undergo follow up appointments for several years to monitor them for any unanticipated side effects associated with the virus. Therefore, several studies have endeavored to find alternative non\u2010viral gene delivery methods that are less expensive, more precise, simple, and safe. 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