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Labial oral microcirculation was evaluated on labial mucosa using oral videocapillaroscopy. The statistical significance was checked with the Mann\u2013Whitney <jats:italic>U<\/jats:italic>\u2010test (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). The analysis of videocapillaroscopic patterns showed statistically significant variations relative to the diameter of the incoming loop; the diameter of the outgoing loop; and loop tortuosity. This study shows that capillary alterations to patients who receive chemotherapy occur in labial oral microcirculation. Clin. 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