{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T23:01:07Z","timestamp":1776726067226,"version":"3.51.2"},"reference-count":188,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,2,21]],"date-time":"2016-02-21T00:00:00Z","timestamp":1456012800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Anatomy"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:p>Klinefelter's syndrome, the most common sex disorder associated with chromosomal aberrations, is characterized by a plethora of clinical features. Parameters for diagnosis of the syndrome are constantly expanding as new anatomical and hormonal abnormalities are noted, yet Klinefelter's remains underdiagnosed and underreported. This review outlines the key anatomical characteristics associated with the syndrome, which are currently used for clinical diagnosis, or may provide means for improving diagnosis in the future. Clin. Anat. 29:606\u2013619, 2016. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/ca.22695","type":"journal-article","created":{"date-parts":[[2016,1,29]],"date-time":"2016-01-29T03:31:54Z","timestamp":1454038314000},"page":"606-619","source":"Crossref","is-referenced-by-count":19,"title":["Anatomical and clinical aspects of Klinefelter's syndrome"],"prefix":"10.1002","volume":"29","author":[{"given":"Rebecca J.","family":"Bird","sequence":"first","affiliation":[{"name":"Department of Anatomy University of Otago Dunedin 9016 New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bradley J.","family":"Hurren","sequence":"additional","affiliation":[{"name":"Department of Anatomy University of Otago Dunedin 9016 New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,21]]},"reference":[{"key":"e_1_2_20_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0223(199704)17:4<363::AID-PD79>3.0.CO;2-O"},{"key":"e_1_2_20_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2605.2008.00921.x"},{"key":"e_1_2_20_4_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-12-0934"},{"key":"e_1_2_20_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2007.120675"},{"key":"e_1_2_20_6_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-07-0310"},{"key":"e_1_2_20_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2011.02246.x"},{"key":"e_1_2_20_8_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ne.09.030186.002041"},{"key":"e_1_2_20_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11065-006-9002-x"},{"key":"e_1_2_20_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2008.03211.x"},{"key":"e_1_2_20_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/13.4.329"},{"key":"e_1_2_20_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2011.02161.x"},{"key":"e_1_2_20_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320450314"},{"key":"e_1_2_20_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1966.00290160014004"},{"key":"e_1_2_20_15_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.82.8.4163"},{"key":"e_1_2_20_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00354965"},{"key":"e_1_2_20_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320480312"},{"key":"e_1_2_20_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(83)91779-8"},{"key":"e_1_2_20_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yfrne.2011.03.001"},{"key":"e_1_2_20_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/ddrr.83"},{"key":"e_1_2_20_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncpuro0775"},{"key":"e_1_2_20_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2011.02274.x"},{"key":"e_1_2_20_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gaq016"},{"key":"e_1_2_20_24_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-0777"},{"key":"e_1_2_20_25_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-0697"},{"key":"e_1_2_20_26_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-021491"},{"key":"e_1_2_20_27_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc06-0145"},{"key":"e_1_2_20_28_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-0367"},{"key":"e_1_2_20_29_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-16-5-689"},{"key":"e_1_2_20_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2010.02131.x"},{"key":"e_1_2_20_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/15.3.185"},{"key":"e_1_2_20_32_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.940577"},{"key":"e_1_2_20_33_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-1954"},{"key":"e_1_2_20_34_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5899-10.2011"},{"key":"e_1_2_20_35_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010-2103"},{"key":"e_1_2_20_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(72)80586-9"},{"key":"e_1_2_20_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1981.tb00709.x"},{"key":"e_1_2_20_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00283733"},{"key":"e_1_2_20_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(16)34961-1"},{"key":"e_1_2_20_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0223(200001)20:1<37::AID-PD748>3.0.CO;2-G"},{"key":"e_1_2_20_41_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-021379"},{"key":"e_1_2_20_42_1","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1037\/0033-2909.118.1.55","article-title":"Human behavioural sex differences: A role for gonadal hormones during early development?","volume":"118","author":"Collaer ML","year":"1995","journal-title":"Psychol Bull"},{"key":"e_1_2_20_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2605.2009.00986.x"},{"key":"e_1_2_20_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpn.2012.01.009"},{"key":"e_1_2_20_45_1","first-page":"717","article-title":"Klinefelter's syndrome and pulmonary disease","volume":"98","author":"Daly JJ","year":"1968","journal-title":"Am Rev Resp Dis"},{"key":"e_1_2_20_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.b.30163"},{"key":"e_1_2_20_47_1","first-page":"91","article-title":"Klinefelter's syndrome and cardiovascular disease","volume":"6","author":"Esposito D","year":"2012","journal-title":"Curr Trends Endocrinol"},{"key":"e_1_2_20_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970040704"},{"key":"e_1_2_20_49_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2.2.142"},{"key":"e_1_2_20_50_1","first-page":"277","volume-title":"The Sex Chromatin","author":"Ferguson\u2010Smith MA.","year":"1966"},{"key":"e_1_2_20_51_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010-1878"},{"key":"e_1_2_20_52_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.84.10.3807"},{"key":"e_1_2_20_53_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.83.1.203"},{"key":"e_1_2_20_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(61)92541-7"},{"key":"e_1_2_20_55_1","first-page":"88","article-title":"Klinefelter's syndrome and mitral valve prolapse. An echocardiographic study in twenty\u2010two patients","volume":"38","author":"Fricke GR","year":"1984","journal-title":"Biomed Pharmacother"},{"key":"e_1_2_20_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(81)92821-X"},{"key":"e_1_2_20_57_1","first-page":"74","article-title":"Bilateral aplasia of the mandibular ramus and condyle in Klinefelter syndrome","volume":"7","author":"Fryns JP","year":"1996","journal-title":"Genet Couns"},{"key":"e_1_2_20_58_1","doi-asserted-by":"publisher","DOI":"10.1002\/1098-2779(2000)6:2<107::AID-MRDD4>3.0.CO;2-2"},{"key":"e_1_2_20_59_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1985.04060050026008"},{"key":"e_1_2_20_60_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-2969"},{"key":"e_1_2_20_61_1","doi-asserted-by":"publisher","DOI":"10.1159\/000232162"},{"key":"e_1_2_20_62_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345650440012201"},{"key":"e_1_2_20_63_1","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1542\/peds.81.6.795","article-title":"Oral and written language abilities of XXY boys: Implications for anticipatory guidance","volume":"81","author":"Graham J","year":"1988","journal-title":"Pediatrics"},{"key":"e_1_2_20_64_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000181506.97839.b0"},{"key":"e_1_2_20_65_1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1302\/0301-620X.61B1.33996","article-title":"Congenital abnormalities and Perthes' disease. Clinical evidence that children with Perthes' disease may have a major congenital defect","volume":"61","author":"Hall DJ","year":"1979","journal-title":"J Bone Joint Surg"},{"key":"e_1_2_20_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2003.12.029"},{"key":"e_1_2_20_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1995.85"},{"key":"e_1_2_20_68_1","first-page":"1025","article-title":"Maternal serum screening for aneuploidy pregnancy by alpha\u2010fetoprotein, hCG and unconjugated estriol","volume":"76","author":"Heyl PS","year":"1990","journal-title":"Obstet Gynecol"},{"key":"e_1_2_20_69_1","doi-asserted-by":"publisher","DOI":"10.5489\/cuaj.2603"},{"key":"e_1_2_20_70_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1983.03330390038028"},{"key":"e_1_2_20_71_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1992.tb02910.x"},{"key":"e_1_2_20_72_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197809000-00004"},{"key":"e_1_2_20_73_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.80.1.31"},{"key":"e_1_2_20_74_1","doi-asserted-by":"publisher","DOI":"10.1002\/1096-8628(20010101)98:1<25::AID-AJMG1015>3.0.CO;2-X"},{"key":"e_1_2_20_75_1","first-page":"100","article-title":"Craniofacial morphology in Klinefelter syndrome: A roentgencephalometric investigation","volume":"15","author":"Ingerslev CH","year":"1978","journal-title":"Cleft Palate J"},{"key":"e_1_2_20_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2008.01.051"},{"key":"e_1_2_20_77_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-1596"},{"key":"e_1_2_20_78_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-1809.1988.tb01084.x"},{"key":"e_1_2_20_79_1","doi-asserted-by":"publisher","DOI":"10.1038\/183302a0"},{"key":"e_1_2_20_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2012.07.1122"},{"key":"e_1_2_20_81_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1939-4640.2003.tb02638.x"},{"key":"e_1_2_20_82_1","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1093\/oxfordjournals.jhered.a108398","article-title":"Taurodont molars and shovel incisors in Klinefelter's syndrome","volume":"64","author":"Keeler C.","year":"1973","journal-title":"J Hered"},{"key":"e_1_2_20_83_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00451449"},{"key":"e_1_2_20_84_1","first-page":"15","article-title":"Syndrome characterized by gynecomastia, aspermatogenesis without a\u2010Leydigism and increased secretion of follicle\u2010stimulating hormone","volume":"26","author":"Klinefelter HF","year":"1942","journal-title":"J Clin Endocrinol Metab"},{"key":"e_1_2_20_85_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-198609000-00012"},{"key":"e_1_2_20_86_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02208039"},{"key":"e_1_2_20_87_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02242951"},{"key":"e_1_2_20_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2004.03.006"},{"key":"e_1_2_20_89_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1211192"},{"key":"e_1_2_20_90_1","doi-asserted-by":"publisher","DOI":"10.1159\/000362414"},{"key":"e_1_2_20_91_1","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1490601"},{"key":"e_1_2_20_92_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-031624"},{"key":"e_1_2_20_93_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2011.02280.x"},{"key":"e_1_2_20_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16678-6"},{"key":"e_1_2_20_95_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.57.11.887-a"},{"key":"e_1_2_20_96_1","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.76.s2.04"},{"key":"e_1_2_20_97_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-19-12-1667"},{"key":"e_1_2_20_98_1","first-page":"193","article-title":"A prospective study of development of children with sex chromosome anomalies: New Haven Study III: The middle years","volume":"18","author":"Leonard MF","year":"1982","journal-title":"Birth Defects Orig Art Ser"},{"key":"e_1_2_20_99_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.96.4.672"},{"key":"e_1_2_20_100_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.10391"},{"key":"e_1_2_20_101_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4389-11.2012"},{"key":"e_1_2_20_102_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00219178"},{"key":"e_1_2_20_103_1","doi-asserted-by":"publisher","DOI":"10.1086\/323763"},{"key":"e_1_2_20_104_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199103000-00001"},{"key":"e_1_2_20_105_1","doi-asserted-by":"publisher","DOI":"10.4103\/1008-682X.125914"},{"key":"e_1_2_20_106_1","doi-asserted-by":"publisher","DOI":"10.3122\/jabfm.2012.05.110232"},{"key":"e_1_2_20_107_1","first-page":"267","article-title":"The effectos of testosterone treatment in Klinefelter's syndrome","volume":"76","author":"Mhyre S","year":"1970","journal-title":"J"},{"key":"e_1_2_20_108_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.102.5.1550"},{"key":"e_1_2_20_109_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1987.5.8.1290"},{"key":"e_1_2_20_110_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1988.tb03447.x"},{"key":"e_1_2_20_111_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-69644-2_22"},{"key":"e_1_2_20_112_1","first-page":"559","article-title":"The association of Klinefelter syndrome and multiple pterygium syndrome: an unusual presentation","volume":"55","author":"Nur BG","year":"2013","journal-title":"Turk J Pediatr"},{"key":"e_1_2_20_113_1","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gam053"},{"key":"e_1_2_20_114_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/324835"},{"key":"e_1_2_20_115_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1202302"},{"key":"e_1_2_20_116_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOU.0b013e32831367c7"},{"key":"e_1_2_20_117_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199802263380905"},{"key":"e_1_2_20_118_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.09.215"},{"key":"e_1_2_20_119_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.10154"},{"key":"e_1_2_20_120_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.54.12.2218"},{"key":"e_1_2_20_121_1","first-page":"321","article-title":"Klinefelter's syndrome and its variants: A hormonal and chromosomal study","volume":"24","author":"Paulsen CA","year":"1968","journal-title":"Recent Prog Horm Res"},{"key":"e_1_2_20_122_1","first-page":"53","article-title":"Testicular dysgenesis affecting the seminiferous tubules principally, with chromatin\u2010positive nuclei","volume":"28","author":"Plunkett ER","year":"1956","journal-title":"Lancet"},{"key":"e_1_2_20_123_1","doi-asserted-by":"publisher","DOI":"10.1038\/35107080"},{"key":"e_1_2_20_124_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech.39.4.330"},{"key":"e_1_2_20_125_1","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gaq027"},{"key":"e_1_2_20_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)69099-2"},{"key":"e_1_2_20_127_1","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1080\/09723757.2012.11886175","article-title":"A data profile of phenotypic features in 72 Klinefelter syndrome (KFS) males","volume":"12","author":"Ranganath V","year":"2012","journal-title":"Int J Hum Genet"},{"key":"e_1_2_20_128_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.80.2.192"},{"key":"e_1_2_20_129_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-595X(82)80008-X"},{"key":"e_1_2_20_130_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.1711640405"},{"key":"e_1_2_20_131_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.b.30772"},{"key":"e_1_2_20_132_1","first-page":"261","article-title":"Summary of clinical findings: profiles of children with 47,XXY, 47,XXX and 47,XYY karyotypes","volume":"15","author":"Robinson A","year":"1979","journal-title":"Birth Defects Orig Artic Ser"},{"key":"e_1_2_20_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(64)90161-8"},{"key":"e_1_2_20_134_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/15.8.1804"},{"key":"e_1_2_20_135_1","doi-asserted-by":"publisher","DOI":"10.1159\/000087313"},{"key":"e_1_2_20_136_1","doi-asserted-by":"publisher","DOI":"10.1177\/002221949602900208"},{"key":"e_1_2_20_137_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.78"},{"key":"e_1_2_20_138_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-198501000-00022"},{"key":"e_1_2_20_139_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2009.03.006"},{"key":"e_1_2_20_140_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(63)80189-4"},{"key":"e_1_2_20_141_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8529(18)30285-8"},{"key":"e_1_2_20_142_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2006.06584.x"},{"key":"e_1_2_20_143_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1462"},{"key":"e_1_2_20_144_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2004.08.018"},{"key":"e_1_2_20_145_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.GIM.0000095626.54201.D0"},{"key":"e_1_2_20_146_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2013.10.013"},{"key":"e_1_2_20_147_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.158.12.1309"},{"key":"e_1_2_20_148_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0223(200005)20:5<390::AID-PD824>3.0.CO;2-B"},{"key":"e_1_2_20_149_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.31354"},{"key":"e_1_2_20_150_1","doi-asserted-by":"publisher","DOI":"10.1002\/ddrr.84"},{"key":"e_1_2_20_151_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.2006.00635.x"},{"key":"e_1_2_20_152_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780200103"},{"key":"e_1_2_20_153_1","first-page":"99","article-title":"Growth and development of children with X and Y chromosome aneuploidy from infancy to pubertal age: The Toronto Study","volume":"18","author":"Stewart DA","year":"1982","journal-title":"Birth Defects Orig Art Ser"},{"key":"e_1_2_20_154_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2011-000650"},{"key":"e_1_2_20_155_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-1809.2001.6520177.x"},{"key":"e_1_2_20_156_1","doi-asserted-by":"crossref","first-page":"6516","DOI":"10.1210\/jc.2005-1077","article-title":"Mortality in patients with Klinefelter syndrome in Britain: A cohort study","volume":"90","author":"Swerdlow AJ","journal-title":"J Clin Endocrinol Metab"},{"key":"e_1_2_20_157_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(59)90558-6"},{"key":"e_1_2_20_158_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2011.02235.x"},{"key":"e_1_2_20_159_1","first-page":"151","article-title":"The spectrum of the behavioral phenotype in boys and adolescents 47,XXY (Klinefelter syndrome)","volume":"8","author":"Tartaglia N","year":"2010","journal-title":"Pediatr Endocrinol"},{"key":"e_1_2_20_160_1","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1542\/peds.59.4.574","article-title":"The early childhood development of 17 boys with sex chromosome anomalies: A prospective study","volume":"59","author":"Tennes K","year":"1977","journal-title":"Pediatrics"},{"key":"e_1_2_20_161_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)55334-5"},{"key":"e_1_2_20_162_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmg028"},{"key":"e_1_2_20_163_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00442070"},{"key":"e_1_2_20_164_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a019004"},{"key":"e_1_2_20_165_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(85)90028-7"},{"key":"e_1_2_20_166_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0801183"},{"key":"e_1_2_20_167_1","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gaq019"},{"key":"e_1_2_20_168_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/11.suppl_4.1"},{"key":"e_1_2_20_169_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001980170158"},{"key":"e_1_2_20_170_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-008-0542-1"},{"key":"e_1_2_20_171_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345880670021401"},{"key":"e_1_2_20_172_1","doi-asserted-by":"publisher","DOI":"10.1177\/000992280104001201"},{"key":"e_1_2_20_173_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-1-42"},{"key":"e_1_2_20_174_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.31103"},{"key":"e_1_2_20_175_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2011.06.077"},{"key":"e_1_2_20_176_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1975.tb01547.x"},{"key":"e_1_2_20_177_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-032006"},{"key":"e_1_2_20_178_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.66.5.628"},{"key":"e_1_2_20_179_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(02)01484-1"},{"key":"e_1_2_20_180_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-0669"},{"key":"e_1_2_20_181_1","doi-asserted-by":"publisher","DOI":"10.1203\/01.pdr.0000219386.31398.c3"},{"key":"e_1_2_20_182_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2010.09.006"},{"key":"e_1_2_20_183_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-031725"},{"key":"e_1_2_20_184_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/112.3.799"},{"key":"e_1_2_20_185_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2350-12-68"},{"key":"e_1_2_20_186_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2007.10.019"},{"key":"e_1_2_20_187_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0387-7604(97)00032-6"},{"key":"e_1_2_20_188_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-1424"},{"key":"e_1_2_20_189_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0960-7692.2001.00583.x"}],"container-title":["Clinical Anatomy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fca.22695","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ca.22695","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T20:15:36Z","timestamp":1696623336000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ca.22695"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,21]]},"references-count":188,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["10.1002\/ca.22695"],"URL":"https:\/\/doi.org\/10.1002\/ca.22695","archive":["Portico"],"relation":{},"ISSN":["0897-3806","1098-2353"],"issn-type":[{"value":"0897-3806","type":"print"},{"value":"1098-2353","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,21]]}}}