{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T14:09:38Z","timestamp":1791468578168,"version":"4.3.4"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,11,10]],"date-time":"2017-11-10T00:00:00Z","timestamp":1510272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Anatomy"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:p>\n                    Gender\u2010affirmation surgery is often the final gender\u2010confirming medical intervention sought by those patients suffering from gender dysphoria. In the male\u2010to\u2010female (MtF) transgendered patient, the creation of esthetic and functional external female genitalia with a functional vaginal channel is of the utmost importance. The aim of this review and meta\u2010analysis is to evaluate the epidemiology, presentation, management, and outcomes of neovaginal complications in the MtF transgender reassignment surgery patients. PUBMED was searched in accordance with PRISMA guidelines for relevant articles (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u2009125). Ineligible articles were excluded and articles meeting all inclusion criteria went on to review and analysis (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200913). Ultimately, studies reported on 1,684 patients with an overall complication rate of 32.5% and a reoperation rate of 21.7% for non\u2010esthetic reasons. The most common complication was stenosis of the neo\u2010meatus (14.4%). Wound infection was associated with an increased risk of all tissue\u2010healing complications. Use of sacrospinous ligament fixation (SSL) was associated with a significantly decreased risk of prolapse of the neovagina. Gender\u2010affirmation surgery is important in the treatment of gender dysphoric patients, but there is a high complication rate in the reported literature. Variability in technique and complication reporting standards makes it difficult to assess the accurately the current state of MtF gender reassignment surgery. Further research and implementation of standards is necessary to improve patient outcomes. Clin. Anat. 31:191\u2013199, 2018. \u00a9 2017 Wiley Periodicals, Inc.\n                  <\/jats:p>","DOI":"10.1002\/ca.23001","type":"journal-article","created":{"date-parts":[[2017,10,23]],"date-time":"2017-10-23T02:16:36Z","timestamp":1508724996000},"page":"191-199","source":"Crossref","is-referenced-by-count":96,"title":["Complications of the neovagina in male\u2010to\u2010female transgender surgery: A systematic review and meta\u2010analysis with discussion of management"],"prefix":"10.1002","volume":"31","author":[{"given":"Paulette Cutruzzula","family":"Dreher","sequence":"first","affiliation":[{"name":"Department of Urology Hahnemann University Hospital\/Drexel University College of Medicine Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4978-7460","authenticated-orcid":false,"given":"Daniel","family":"Edwards","sequence":"additional","affiliation":[{"name":"Department of Urology Hahnemann University Hospital\/Drexel University College of Medicine Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaun","family":"Hager","sequence":"additional","affiliation":[{"name":"Department of Urology Hahnemann University Hospital\/Drexel University College of Medicine Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margeaux","family":"Dennis","sequence":"additional","affiliation":[{"name":"Lake Erie College of Osteopathic Medicine Erie Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andie","family":"Belkoff","sequence":"additional","affiliation":[{"name":"Drexel University College of Medicine Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamie","family":"Mora","sequence":"additional","affiliation":[{"name":"Department of Surgery Hahnemann University Hospital\/Drexel University College of Medicine Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Tarry","sequence":"additional","affiliation":[{"name":"Department of Urology Hahnemann University Hospital\/Drexel University College of Medicine Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathy L.","family":"Rumer","sequence":"additional","affiliation":[{"name":"Department of Surgery Hahnemann University Hospital\/Drexel University College of Medicine Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,11,10]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"223","article-title":"Genital reassignment on two male transvestites","volume":"18","author":"Abraham F.","year":"1931","journal-title":"Int J Transgenderism"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-012-0867-9"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2012.12.030"},{"key":"e_1_2_10_5_1","first-page":"12","article-title":"Transvestitism and transexualism","volume":"7","author":"Benjamin H.","year":"1953","journal-title":"Int J Sexol"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsm.12914"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-1591.33731"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000435844.95551.35"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2016.07.012"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2004.04.055"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2007.07017.x"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1008161"},{"key":"e_1_2_10_13_1","doi-asserted-by":"crossref","unstructured":"GreenR FlemingDT.1990. 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