{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T06:58:58Z","timestamp":1790319538481,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,7,8]],"date-time":"2020-07-08T00:00:00Z","timestamp":1594166400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Anatomy"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The motion of the brain relative to the skull is influenced by the architecture of the subarachnoid space (SAS), and in particular, by the arachnoid trabeculae. In previous studies of these structures, specific shapes were identified. However, the work presented here shows much finer detail of the SAS geometries using SEM and TEM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>These images were acquired by maintaining the SAS structure of a rat using glutaraldehyde formaldehyde to strengthen the tissues via crosslinking with the biological proteins.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The results showed the detailed shape of five dominant arachnoid trabeculae structures: single strands, branched strands, tree like shapes, sheets, and trabecular networks. Each of these architectures would provide a different response when exposed to a tensile load and would provide different levels of resistance to the flow of the cerebrospinal fluid (CSF) within the SAS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This very detailed level of geometric information will therefore allow more accurate finite element models of the SAS to be developed.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ca.23635","type":"journal-article","created":{"date-parts":[[2020,6,10]],"date-time":"2020-06-10T02:36:45Z","timestamp":1591756605000},"page":"40-50","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Subarachnoid space trabeculae architecture"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2355-9387","authenticated-orcid":false,"given":"Parisa","family":"Saboori","sequence":"first","affiliation":[{"name":"Department of Mechanical Engineering Manhattan College  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901610404"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X16655550"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/02688690701447420"},{"key":"e_1_2_6_5_1","first-page":"29","article-title":"Micromechanical heterogeneity of the rat pia arachnoid complex","volume":"100","author":"Fabris G.","year":"2019","journal-title":"ActaBiomater"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001250202"},{"issue":"2","key":"e_1_2_6_7_1","first-page":"54","article-title":"Fluid structure interaction of traumatic brain injury: Effects of material properties on SAS trabeculae","volume":"14","author":"Ghaffari M.","year":"2014","journal-title":"International Journal of Modern Engineering"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1115\/1.3005171"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1092300103"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001310102"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091710102"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2010.0032"},{"key":"e_1_2_6_13_1","volume-title":"Histology and cell biology an introduction to pathology","author":"Kierszenbaum L. 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