{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T01:04:10Z","timestamp":1771463050175,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T00:00:00Z","timestamp":1665964800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Anatomy"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In this cadaver\u2010based study, we aimed to present a novel approach to pulmonary valve (PV) anatomy, morphometry, and geometry to offer comprehensive information on PV structure. The 182 autopsied human hearts were investigated morphometrically. The largest PV area was seen for the coaptation center plane, followed by basal ring and the tubular plane (626.7\u2009\u00b1\u2009191.7\u2009mm<jats:sup>2<\/jats:sup> vs. 433.9\u2009\u00b1\u2009133.6\u2009mm<jats:sup>2<\/jats:sup> vs. 290.0\u2009\u00b1\u2009110.1\u2009mm<jats:sup>2<\/jats:sup>, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). In all leaflets, fenestrations are noted and occur in 12.5% of PVs. Only in 31.3% of PVs, the coaptation center is located in close vicinity of the PV geometric center. Similar\u2010sized sinuses were found in 35.7% of hearts, in the remaining cases, significant heterogeneity was seen in size. The mean sinus depth was: left anterior 15.59\u2009\u00b1\u20092.91\u2009mm, posterior: 16.04\u2009\u00b1\u20092.82\u2009mm and right anterior sinus: 16.21\u2009\u00b1\u20092.81\u2009mm and the mean sinus height: left anterior 15.24\u2009\u00b1\u20093.10\u2009mm, posterior: 19.12\u2009\u00b1\u20093.79\u2009mm and right anterior sinus: 18.59\u2009\u00b1\u20094.03\u2009mm. For males, the mean pulmonary root perimeters and areas were significantly larger than those for females. Multiple forward stepwise regression model showed that anthropometric variables might predict the coaptation center plane (sex, age, and heart weight; R<jats:sup>2<\/jats:sup>\u00a0=\u00a033.8%), tubular plane (sex, age, and BSA; <jats:italic>R<\/jats:italic><jats:sup><jats:italic>2<\/jats:italic><\/jats:sup>\u00a0=\u00a020.5%) and basal ring level area (heart weight and sex; <jats:italic>R<\/jats:italic><jats:sup><jats:italic>2<\/jats:italic><\/jats:sup>\u00a0=\u00a017.1%). In conclusion, the largest pulmonary root area is observed at the coaptation center plane, followed by the basal ring and tubular plane. The PV geometric center usually does not overlap valve coaptation center. Significant heterogeneity is observed in the size of sinuses and leaflets within and between valves. Anthropometric variables may be used to predict pulmonary root dimensions.<\/jats:p>","DOI":"10.1002\/ca.23959","type":"journal-article","created":{"date-parts":[[2022,10,4]],"date-time":"2022-10-04T09:59:03Z","timestamp":1664877543000},"page":"234-241","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Pulmonary valve morphometry revisited: Clinical implications for valvular and supravalvular interventions"],"prefix":"10.1002","volume":"36","author":[{"given":"Maciej","family":"Lis","sequence":"first","affiliation":[{"name":"HEART \u2010 Heart Embryology and Anatomy Research Team, Department of Anatomy Jagiellonian University Medical College  Cracow Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7691-8174","authenticated-orcid":false,"given":"Agata","family":"Krawczyk\u2010O\u017c\u00f3g","sequence":"additional","affiliation":[{"name":"HEART \u2010 Heart 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