{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T13:37:38Z","timestamp":1762609058296,"version":"3.40.5"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,12,15]],"date-time":"2022-12-15T00:00:00Z","timestamp":1671062400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Anatomy"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Nasopharyngeal depth (ND) prediction is clinically relevant in performing medical procedures, and in enhancing technique accuracy and patient safety. Nonetheless, clinical predictive variables and normative data in adults remain limited. This study aimed to determine normative data on ND and its correlation to external facial measurements. A multicenter cross\u2010sectional study obtained data from adults presenting to otolaryngology clinics at five sites in Canada, Italy, and Spain. Investigators compared endoscopically measured depth from the nasal sill (soft tissue between the nasal ala and columella) to nasopharynx along the nasal floor to the \u201ccurved distance from the alar\u2010facial groove along the face to the tragus\u201d and \u201cdistance from the tragus to a plane perpendicular to the philtrum.\u201d When sinus computed tomography images were available, the distance from the nasopharynx to the nasal sill was also collected. 371 patients participated in the study (41% women; 51\u2009years old, SD 18). Average ND was 9.4\u00a0cm (SD 0.86) and 10.1\u00a0cm (SD 0.9) for women and men, respectively (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001; 95% CI 0.46\u20130.86). Perpendicular distance was strongly correlated to ND (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.775; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), with an average underestimation of 0.1\u00a0cm (SD 0.65; 95% CI 0.06\u20130.2). The equation: ND (cm)\u00a0=\u00a0perpendicular distance*0.773\u2009+\u20092.344, generated from 271 randomly selected participants, and validated on 100 participants, resulted in a 0.03\u2009cm prediction error (SD 0.61; 95% CI \u22120.08\u20130.16). Nasopharyngeal depth can be approximated by the distance from the tragus to a plane perpendicular to the philtrum.<\/jats:p>","DOI":"10.1002\/ca.23985","type":"journal-article","created":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T14:19:28Z","timestamp":1670509168000},"page":"285-290","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["How deep do you go? Clinical prediction of nasopharyngeal depth based on facial measurements"],"prefix":"10.1002","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2802-7232","authenticated-orcid":false,"given":"Alexander","family":"Dickie","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Western University  London Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6190-1425","authenticated-orcid":false,"given":"Taciano","family":"Rocha","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Western University  London Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1251-0185","authenticated-orcid":false,"given":"Antonino","family":"Maniaci","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences and Advanced Technologies GF Ingrassia ENT Section University of Catania  Catania Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1975-6153","authenticated-orcid":false,"given":"Angelo","family":"Ingrassia","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences and Advanced Technologies GF Ingrassia ENT Section University of Catania  Catania Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1457-6871","authenticated-orcid":false,"given":"Alberto","family":"Maria Saibene","sequence":"additional","affiliation":[{"name":"Otolaryngology Unit, Santi Paolo e Carlo Hospital, Department of Health Sciences Universit\u00e0 Degli Studi di Milano  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2705-5493","authenticated-orcid":false,"given":"Sofia","family":"Spagnolini","sequence":"additional","affiliation":[{"name":"Otolaryngology Unit, Santi Paolo e Carlo Hospital, Department of Health Sciences Universit\u00e0 Degli Studi di Milano  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1879-5580","authenticated-orcid":false,"given":"Luca Giovanni","family":"Locatello","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Careggi University Hospital  Florence Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6463-1459","authenticated-orcid":false,"given":"Manuel","family":"Tucciarone","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology University Hospital of Jerez  C\u00e1diz Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5939-5372","authenticated-orcid":false,"given":"Thomas","family":"Radulesco","sequence":"additional","affiliation":[{"name":"Aix\u2010Marseille Univ, APHM, IUSTI, CNRS La Conception University Hospital, Department of Oto\u2010Rhino\u2010Laryngology Head and Neck Surgery  Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0258-3142","authenticated-orcid":false,"given":"Brian","family":"Rotenberg","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Western University  London Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5825-2759","authenticated-orcid":false,"given":"Leigh J","family":"Sowerby","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Western University  London Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,12,15]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_6_2_1","DOI":"10.3390\/diagnostics11071257"},{"unstructured":"CDC. 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