{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T21:18:44Z","timestamp":1782163124724,"version":"3.54.5"},"reference-count":36,"publisher":"Wiley","license":[{"start":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T00:00:00Z","timestamp":1706140800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Anatomy"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cone\u2010Beam Computed Tomography\u2010Sialography (Sialo\u2010CBCT) is used to demonstrate salivary ductal structure. This study aimed to conduct a volumetric analysis of the anatomical morphology of Normal\u2010Appearing Glands (NAGs) in parotid sialo\u2010CBCT. Our retrospective study included 14 parotid sialo\u2010CBCT scans interpreted as NAGs in 11 patients with salivary gland impairment. The main duct length and width, as well as number and width of secondary and tertiary ducts were manually evaluated. We found that the main parotid duct showed an average width of 1.39 mm, 1.15 mm, and 0.98\u2009mm, for the proximal, middle and distal thirds, respectively. The arborization pattern showed approximately 20% more tertiary (average number 11.1\u2009\u00b1\u20092.7) than secondary ducts (average number 9.0\u2009\u00b1\u20092.4) and approximately 8% narrower tertiary ducts (average width 0.65\u2009\u00b1\u20090.11\u2009mm) compared to the secondary ducts (average width 0.77\u2009\u00b1\u20090.14\u2009mm). Our anatomical analysis of NAGs in parotid sialo\u2010CBCT demonstrated progressive narrowing of the main duct and increasing arborization and decreasing lumen size starting from the primary to the tertiary ducts. This is the most updated study regarding the anatomy of the parotid glands as demonstrated in sialo\u2010CBCT. Our results may provide clinicians with the basic information for understanding aberration from normal morphology, as seen in salivary gland pathologies as well facilitate planning of treatment strategies, such as minimally invasive sialo\u2010endoscopies, commonly practiced today.<\/jats:p>","DOI":"10.1002\/ca.24136","type":"journal-article","created":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T11:58:26Z","timestamp":1706183906000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The anatomical pattern of ductal arborization in parotid glands using cone\u2010beam computerized sialography"],"prefix":"10.1002","author":[{"given":"Tevel","family":"Amiel","sequence":"first","affiliation":[{"name":"Oral Maxillofacial Imaging, Department of Oral Medicine, Sedation and Imaging, Faculty of Dental Medicine, Hadassah Medical Center Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oren","family":"Shauly","sequence":"additional","affiliation":[{"name":"School of Computer Science and Engineering The Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ella Gilenson","family":"Istoyler","sequence":"additional","affiliation":[{"name":"Oral Maxillofacial Imaging, Department of Oral Medicine, Sedation and Imaging, Faculty of Dental Medicine, Hadassah Medical Center Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Alterman","sequence":"additional","affiliation":[{"name":"Oral Maxillofacial Surgery Department, Hadassah Medical Center, Faculty of Dental Medicine Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naama","family":"Keshet","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Sedation and Imaging, Faculty of Dental Medicine, Hadassah Medical Center Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sigal","family":"Mazor","sequence":"additional","affiliation":[{"name":"Community Dentistry Department, Hadassah Faculty of Dental Medicine Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Pikovsky","sequence":"additional","affiliation":[{"name":"Oral Medicine Unit, Oral Maxillofacial Surgery Department Barzilai Medical Center  Ashkelon Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doron J.","family":"Aframian","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Sedation and Imaging, Faculty of Dental Medicine, Hadassah Medical Center Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leo","family":"Joskowicz","sequence":"additional","affiliation":[{"name":"School of Computer Science and Engineering The Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2218-3966","authenticated-orcid":false,"given":"Chen","family":"Nadler","sequence":"additional","affiliation":[{"name":"Oral Maxillofacial Imaging, Department of Oral Medicine, Sedation and Imaging, Faculty of Dental Medicine, Hadassah Medical Center Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,25]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3290\/j.qi.b1492217"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.5624\/isd.2013.43.1.17"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12736"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/cpf.12199"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2015.02.024"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40136-020-00299-2"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr.20150431"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-023-03159-9"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12911"},{"key":"e_1_2_10_11_1","article-title":"Conventional MRI techniques combined with MR sialography on T2\u20103D\u2010DRIVE in Sj\u00f6gren syndrome","volume":"8","author":"Ren Y.","year":"2015","journal-title":"International Journal of Clinical and Experimental Medicine"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kez079"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/028418517301400104"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/lio2.33"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.13298"},{"key":"e_1_2_10_16_1","first-page":"1","volume-title":"Histology, in: histopathology of the salivary glands","author":"Henrik H.","year":"2014"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(68)90351-4"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr\/81159071"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr.20110319"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2020.101592"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612823666170215110648"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12946"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr.1978.0011"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.3174\/ng.3140086"},{"key":"e_1_2_10_25_1","volume-title":"Idiopathic adulthood ductopenia: an update","author":"Ludwig J.","year":"1998"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1067\/moe.2002.121163"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1653"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199703203361204"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2008.05.011"},{"key":"e_1_2_10_30_1","volume-title":"Radiology of salivary glands","author":"Rabinov K.","year":"1984"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1080\/21681163.2020.1866670"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1601-0825.2002.2o837.x"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9082492"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1249\/01.MSS.0000139797.26760.06"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-010-2038-6"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(98)90294-3"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm-20-3295"}],"container-title":["Clinical Anatomy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ca.24136","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T11:58:34Z","timestamp":1706183914000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ca.24136"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,25]]},"references-count":36,"alternative-id":["10.1002\/ca.24136"],"URL":"https:\/\/doi.org\/10.1002\/ca.24136","archive":["Portico"],"relation":{},"ISSN":["0897-3806","1098-2353"],"issn-type":[{"value":"0897-3806","type":"print"},{"value":"1098-2353","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,25]]},"assertion":[{"value":"2023-10-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"ca.24136"}}