{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T08:06:33Z","timestamp":1753862793579,"version":"3.41.2"},"reference-count":41,"publisher":"Wiley","license":[{"start":{"date-parts":[[2024,3,12]],"date-time":"2024-03-12T00:00:00Z","timestamp":1710201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Anatomy"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The existence, composition, and continuity of the medial wall of the cavernous sinus (MWCS) have been extensively studied and debated. However, the precise nature of this membrane remains unknown. Understanding the anatomical characteristics of the MWCS is crucial, notably in relation to pituitary adenomas, which often invade the cavernous sinus. Indeed, surgical treatment of those tumors is frequently incomplete because of such invasion. The anatomical and molecular basis of the peculiar and often lateralized tropism of adenomatous cells to the cavernous sinus is not yet understood and it has been suggested repeatedly that the MWCS is physiologically frail. During the past three decades, there have been several conflicting accounts of the existence, composition, and continuity of this medial wall, but methodological differences and varying definitions could have contributed to the current lack of consensus regarding it. The aim of this systematic review was to summarize previously published data concerning the existence, anatomy, composition, and continuity of the MWCS.<\/jats:p>","DOI":"10.1002\/ca.24152","type":"journal-article","created":{"date-parts":[[2024,3,12]],"date-time":"2024-03-12T07:15:05Z","timestamp":1710227705000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Anatomy of the medial wall of the cavernous sinus: A systematic review of the literature"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3055-996X","authenticated-orcid":false,"given":"Etienne","family":"Lefevre","sequence":"first","affiliation":[{"name":"Physiologie et Physiopathologie Endocriniennes Paris\u2010Saclay University, INSERM U1185  Le Kremlin\u2010Bic\u00eatre France"},{"name":"Department of Neurosurgery, APHP Groupe Hospitalier Piti\u00e9\u2010Salp\u00eatri\u00e8re  Paris France"},{"name":"Laboratory of Anatomy Sorbonne Universit\u00e9  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie","family":"Dupont","sequence":"additional","affiliation":[{"name":"Laboratory of Anatomy Sorbonne Universit\u00e9  Paris France"},{"name":"Department of Neurology, APHP Groupe Hospitalier Piti\u00e9\u2010Salp\u00eatri\u00e8re  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominique","family":"Liguoro","sequence":"additional","affiliation":[{"name":"Neurosurgery Department A University Hospital of Bordeaux  Bordeaux France"},{"name":"Laboratory of Anatomy Universit\u00e9 de Bordeaux  Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fanny","family":"Chasseloup","sequence":"additional","affiliation":[{"name":"Physiologie et Physiopathologie Endocriniennes Paris\u2010Saclay University, INSERM U1185  Le Kremlin\u2010Bic\u00eatre France"},{"name":"Service d'Endocrinologie et des Maladies de la Reproduction Centre de R\u00e9f\u00e9rence des maladies Rares de l'Hypophyse, H\u00f4pital de Bic\u00eatre  Le Kremlin\u2010Bic\u00eatre France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Kamenicky","sequence":"additional","affiliation":[{"name":"Physiologie et Physiopathologie Endocriniennes Paris\u2010Saclay University, INSERM U1185  Le Kremlin\u2010Bic\u00eatre France"},{"name":"Service d'Endocrinologie et des Maladies de la Reproduction Centre de R\u00e9f\u00e9rence des maladies Rares de l'Hypophyse, H\u00f4pital de Bic\u00eatre  Le Kremlin\u2010Bic\u00eatre France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0826-7004","authenticated-orcid":false,"given":"Paul","family":"Roblot","sequence":"additional","affiliation":[{"name":"Neurosurgery Department A University Hospital of Bordeaux  Bordeaux France"},{"name":"Laboratory of Anatomy Universit\u00e9 de Bordeaux  Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,3,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1007\/s00276-010-0651-3","article-title":"Endoscopic anatomy and approaches of the cavernous sinus: Cadaver study","volume":"32","author":"Abuzayed B.","year":"2010","journal-title":"Surgical and Radiologic Anatomy"},{"key":"e_1_2_7_3_1","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1055\/s-0036-1598022","article-title":"Cavernous sinus involvement by pituitary adenomas: Clinical implications and outcomes of endoscopic endonasal resection","volume":"78","author":"Ajlan A.","year":"2017","journal-title":"Journal of Neurological Surgery Part B: Skull Base"},{"key":"e_1_2_7_4_1","first-page":"827","article-title":"Endoscopic endonasal cavernous sinus surgery: An anatomic study","volume":"48","author":"Alfieri A.","year":"2001","journal-title":"Neurosurgery"},{"key":"e_1_2_7_5_1","doi-asserted-by":"crossref","first-page":"e139","DOI":"10.1016\/j.wneu.2021.12.023","article-title":"From above and below: The microsurgical anatomy of endoscopic endonasal and transcranial microsurgical approaches to the Parasellar region","volume":"159","author":"Almeida J. 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