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Due to a paucity of literature examining the gross anatomical relationships between endopelvic fascia and autonomic nerves in adult female pelvises, it remains unknown whether defects in endopelvic fascia predisposing pelvic organ prolapse and\/or manipulation of endopelvic fascia during prolapse repair may be the cause of prolapse\u2010related pelvic pain and sexual dysfunction. Through the dissection of formalin\u2010fixed hemipelvises (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200910) the present study aimed to map the loci of the visceral branches of the inferior hypogastric plexus and associate them with endopelvic fascia of the female pelvis. In all specimens, two gross bundles of autonomic nerves were identified within pubocervical fascia traveling caudally to innervate the clitoral crura, vestibular bulbs, and anterior vaginal wall. Moreover, a distinct bundle was found traveling within the rectovaginal septum innervating the posterior vaginal wall. Immunohistochemical staining for S100 protein confirmed the presence of nerves and ganglia within pubocervical fascia that were localized near the vaginal arteries. Additionally, our dissections revealed that the visceral branches of the inferior hypogastric plexus can be stratified to correspond to different named components of endopelvic fascia. Clinically, our results provide a robust anatomical characterization that will inform the development of surgical approaches to reduce the risk of pelvic neuropathy during vaginal prolapse surgery.\n                  <\/jats:p>","DOI":"10.1002\/ca.70028","type":"journal-article","created":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T12:55:26Z","timestamp":1757076926000},"page":"672-682","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Autonomic Plexuses of the Female Sexual Organs Travel Within Pubocervical and Rectovaginal [Endopelvic] Fascia: A Rationale for \u2018Nerve\u2010Aware\u2019 Vaginal Prolapse Repair"],"prefix":"10.1002","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-7699-7903","authenticated-orcid":false,"given":"Stephen","family":"Magliocchetti","sequence":"first","affiliation":[{"name":"Department of Anatomy &amp; Cell Biology Schulich School of Medicine &amp; Dentistry, Western University  London Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Laxer","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine &amp; Pathobiology Temerty Faculty of Medicine, University of Toronto  Toronto Ontario Canada"},{"name":"Arthur and Sonia Labatt Brain Tumour Research Center The Hospital for Sick Children  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leyla","family":"Spennato","sequence":"additional","affiliation":[{"name":"Department of Anatomy &amp; Cell Biology Schulich School of Medicine &amp; Dentistry, Western University  London Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norah","family":"Alturki","sequence":"additional","affiliation":[{"name":"London Health Sciences Research Centre  London Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Queena","family":"Chou","sequence":"additional","affiliation":[{"name":"London Health Sciences Research Centre  London Ontario Canada"},{"name":"Department of Obstetrics &amp; Gynaecology Schulich School of Medicine &amp; Dentistry, Western University  London Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tyler S.","family":"Beveridge","sequence":"additional","affiliation":[{"name":"Department of Anatomy &amp; Cell Biology Schulich School of Medicine &amp; Dentistry, Western University  London Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,5]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Grant's Atlas of Anatomy","author":"Agur A. 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