{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T06:29:20Z","timestamp":1786343360241,"version":"build-2736575974"},"reference-count":51,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T00:00:00Z","timestamp":1786233600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T00:00:00Z","timestamp":1786233600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Anatomy"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The present study aimed to evaluate the developmental morphometry of the paranasal sinuses using computed tomography (CT) in subjects aged 1\u201325\u2009years and to characterize age\u2010related changes in sinus dimensions, volume, and surface area throughout childhood, adolescence, and young adulthood. This retrospective CT\u2010based study included 250 subjects (125 females and 125 males) without radiologic evidence of sinonasal pathology. Bilateral morphometric analyses of the frontal, sphenoid, maxillary, and ethmoid sinuses were performed using multiplanar CT images and three\u2010dimensional reconstructions. Measurements included anteroposterior, mediolateral, and superoinferior diameters, sinus volume, and sinus surface area. Significant age\u2010related differences were identified for all morphometric parameters of the frontal, sphenoid, maxillary, and ethmoid sinuses (all\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05). The frontal sinus demonstrated the latest developmental onset, with no measurable pneumatization during infancy and first detectable development at 5\u2009years of age. In contrast, the maxillary and ethmoid sinuses were identifiable in most subjects during infancy, whereas sphenoid sinus pneumatization was identifiable at 2\u2009years of age. Progressive enlargement of sinus dimensions, volume, and surface area was observed throughout childhood and adolescence, with relative stabilization of most morphometric measurements between the postpubescent and young adult groups. Paranasal sinus morphology demonstrates substantial age\u2010related developmental variation from infancy to young adulthood. These findings provide comprehensive morphometric reference data regarding paranasal sinus maturation and may contribute to improved radiologic interpretation, developmental assessment, and safer surgical planning in pediatric and young adult populations.\n                  <\/jats:p>","DOI":"10.1002\/ca.70201","type":"journal-article","created":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T05:56:02Z","timestamp":1786341362000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Developmental Morphometry of the Paranasal Sinuses in Subjects Aged 1\u201325\u2009Years: A Computed Tomography Study"],"prefix":"10.1002","author":[{"given":"Ceyda \u015eevval","family":"\u00c7etin","sequence":"first","affiliation":[{"name":"Department of Anatomy, Health Sciences Institute Gaziantep University  Gaziantep T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5726-9372","authenticated-orcid":false,"given":"Asl\u0131han","family":"Arta\u015f","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Radiology, Faculty of Dentistry Gaziantep University  Gaziantep T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Atada\u011f","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Bossan Hospital  Gaziantep T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6mer Faruk","family":"Cihan","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Faculty of Medicine Gaziantep University  Gaziantep T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4932-8758","authenticated-orcid":false,"given":"Orhan","family":"Beger","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Faculty of Medicine Gaziantep University  Gaziantep T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,9]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903\u2010025\u201007128\u20102"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010025\u201013624\u2010w"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jobcr.2025.12.001"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2011.25.3552"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2022.111327"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00381\u2010024\u201006574\u20107"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537\u2010199309000\u201000008"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903\u2010026\u201008000\u20107"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/tomography12020015"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330\u2010001\u20101218\u20109"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2016.10.022"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1227\/ons.0000000000001772"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215125102922"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000002304"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2006.09.003"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2012.05.001"},{"key":"e_1_2_13_18_1","volume-title":"Understanding Motor Development: Infants, Children, Adolescents, Adults","author":"Goodway J. 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