{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T06:17:35Z","timestamp":1787811455012,"version":"build-2784847793"},"reference-count":28,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Anatomy"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The esophagogastric junction (EGJ) is the anatomical zone where the esophagus ends and the stomach begins. Its competence in preventing gastro\u2010esophageal reflux has been shown to depend on a number of factors which have been extensively investigated and widely accepted. This study describes two previously unreported features that show anatomical variation around the EGJ: (1) posterior pericardio\u2010esophageal (PE) attachment, and (2) posterior location of the gastric fundus relative to the intra\u2010abdominal esophagus. Measurements and observations were made on 60 formalin\u2010embalmed full\u2010body cadaveric donors from 2023 to 2026. Total pericardial (TP) and PE attachment lengths were measured along a standardized craniocaudal line. The posterior location of the gastric fundus was assessed using a binary scale. Measurements were made by two investigators. Inter\u2010observer agreement was analyzed using intraclass correlation coefficients or Cohen's kappa (\n                    <jats:italic>\u03ba<\/jats:italic>\n                    ). The mean age at death of all donors examined was 87.22\u2009\u00b1\u20098.11\u2009years (range 68\u2013101), with 31 females. For the posterior pericardio\u2010esophageal attachment study group, TP was measurable in 45 donors with a mean TP of 117.3\u2009\u00b1\u200910.66\u2009mm. PE attachment was present in 24.4% (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200911\/45), with a mean length of 36.12\u2009\u00b1\u20099.72\u2009mm, and proportional attachment (PE\/TP) of 29.81%\u2009\u00b1\u20099.23%. For the gastric fundus study group, posterior location was assessed in 58 donors. Posterior location was present in 53.4% (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200931\/58), with high inter\u2010observer agreement in double\u2010rated cases (\n                    <jats:italic>\u03ba<\/jats:italic>\n                    \u2009=\u20090.946). There was no association between presence of PE attachment and posterior fundus location (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20091.00). This study found that PE attachment was present in 24.4% of the donors investigated, which could be relevant to hiatus hernia pathophysiology. Posterior location of the gastric fundus was observed in just over 50% of donors, and might theoretically affect competence at the EGJ. Further in\u00a0vivo and in dynamic imaging studies would be required to demonstrate any potential effects on the EGJ.\n                  <\/jats:p>","DOI":"10.1002\/ca.70219","type":"journal-article","created":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T05:25:35Z","timestamp":1787808335000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Observations on Two Previously Unreported Anatomical Factors Relating to the Esophagogastric Junction"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-0012-2921","authenticated-orcid":false,"given":"Yuhan","family":"Guo","sequence":"first","affiliation":[{"name":"School of Clinical Medicine University of Cambridge  Cambridge UK"},{"name":"Human Anatomy Centre, Department of Physiology, Development and Neuroscience University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandan","family":"Sekhon","sequence":"additional","affiliation":[{"name":"School of Clinical Medicine University of Cambridge  Cambridge UK"},{"name":"Human Anatomy Centre, Department of Physiology, Development and Neuroscience University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Sparks","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Medical School University of P\u00e9cs  P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Brown","sequence":"additional","affiliation":[{"name":"Human Anatomy Centre, Department of Physiology, Development and Neuroscience University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3621-9445","authenticated-orcid":false,"given":"Cecilia","family":"Brassett","sequence":"additional","affiliation":[{"name":"Human Anatomy Centre, Department of Physiology, Development and Neuroscience University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,26]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00180919"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2008.02.003"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2006.124032"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.143701"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/26345161231174246"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.187583"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004649900480"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.13168"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.22091"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01321777"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199703273361306"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.28.12.1564"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1159\/000200561"},{"key":"e_1_2_11_15_1","volume-title":"Netter Atlas of Human Anatomy: Classic Regional Approach","author":"Netter F. 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B.","year":"1987","journal-title":"Acta Chirurgica Scandinavica"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11748\u2010021\u201001615\u20103"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10388\u2010018\u20100625\u20109"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12010"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658\u2010198304000\u201000002"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2017.03.172"},{"key":"e_1_2_11_27_1","volume-title":"Snell's Clinical Anatomy by Regions","author":"Wineski L. 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