{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T21:30:12Z","timestamp":1792445412285,"version":"4.5.0"},"reference-count":30,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"9","license":[{"start":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T00:00:00Z","timestamp":1690156800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"the Institut National du Cancer","award":["2016\u2010101"],"award-info":[{"award-number":["2016\u2010101"]}]},{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["200\u20102017\u201096189"],"award-info":[{"award-number":["200\u20102017\u201096189"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006505","name":"Swiss Re","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006505","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013362","name":"Swiss Cancer Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013362","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000048","name":"American Cancer Society","doi-asserted-by":"publisher","award":["35327"],"award-info":[{"award-number":["35327"]}],"id":[{"id":"10.13039\/100000048","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Commun"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Esophageal cancer survival is poor worldwide, though there is some variation. Differences in the distribution of anatomical sub\u2010site and morphological sub\u2010type may help explain international differences in survival for all esophageal cancers combined. We estimated survival by anatomic sub\u2010site and morphological sub\u2010type to understand further the impact of topography and morphology on international comparisons of esophageal cancer survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">We estimated age\u2010standardized one\u2010year and five\u2010year net survival among adults (15\u201099 years) diagnosed with esophageal cancer in each of 60 participating countries to monitor survival trends by calendar period of diagnosis (2000\u20102004, 2005\u20102009, 2010\u20102014), sub\u2010site, morphology, and sex.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">For adults diagnosed during 2010\u20102014, tumors in the lower third of the esophagus were the most common, followed by tumors of overlapping sub\u2010site and sub\u2010site not otherwise specified. The proportion of squamous cell carcinomas diagnosed during 2010\u20102014 was generally higher in Asian countries (50%\u201090%), while adenocarcinomas were more common in Europe, North America and Oceania (50%\u201060%). From 2000\u20102004 to 2010\u20102014, the proportion of squamous cell carcinoma generally decreased, and the proportion of adenocarcinoma increased. Over time, there were few improvements in age\u2010standardized five\u2010year survival for each sub\u2010site. Age\u2010standardized one\u2010year survival was highest in Japan for both squamous cell carcinoma (67.7%) and adenocarcinoma (69.0%), ranging between 20%\u201060% in most other countries. Age\u2010standardized five\u2010year survival from squamous cell carcinoma and adenocarcinoma was similar for most countries included, around 15%\u201020% for adults diagnosed during 2010\u20102014, though international variation was wider for squamous cell carcinoma. In most countries, survival for both squamous cell carcinoma and adenocarcinoma increased by less than 5% between 2000\u20102004 and 2010\u20102014.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Esophageal cancer survival remains poor in many countries. The distributions of sub\u2010site and morphological sub\u2010type vary between countries, but these differences do not fully explain international variation in esophageal cancer survival.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cac2.12457","type":"journal-article","created":{"date-parts":[[2023,7,25]],"date-time":"2023-07-25T00:56:16Z","timestamp":1690246576000},"page":"963-980","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Worldwide trends in esophageal cancer survival, by sub\u2010site, morphology, and sex: an analysis of 696,974 adults diagnosed in 60 countries during 2000\u20102014 (CONCORD\u20103)"],"prefix":"10.34133","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0132-1108","authenticated-orcid":false,"given":"Melissa","family":"Matz","sequence":"first","affiliation":[{"name":"London School of Hygiene and Tropical Medicine","place":["Greater London, United\u00a0Kingdom"]},{"name":"London WC1E 7HT","place":["Greater London, United\u00a0Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikhail","family":"Valkov","sequence":"additional","affiliation":[{"name":"Northern State Medical University, Arkhangelsk","place":["Arkhangelsk Oblast, Russia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"\u0160ekerija","sequence":"additional","affiliation":[{"name":"Croatian Institute of Public Health, Zagreb","place":["Zagreb County, Croatia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Luttman","sequence":"additional","affiliation":[{"name":"Bremen Cancer Registry","place":["Bremen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adele","family":"Caldarella","sequence":"additional","affiliation":[{"name":"Istituto per lo studio e la prevenzione oncologica","place":["Florence, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel P","family":"Coleman","sequence":"additional","affiliation":[{"name":"London School of Hygiene and Tropical Medicine","place":["Greater London, United\u00a0Kingdom"]},{"name":"London WC1E 7HT","place":["Greater London, United\u00a0Kingdom"]},{"name":"University College London Hospitals NHS Foundation Trust, London NW1 2BU","place":["Greater London, United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Allemani","sequence":"additional","affiliation":[{"name":"London School of Hygiene and Tropical Medicine","place":["Greater London, United\u00a0Kingdom"]},{"name":"London WC1E 7HT","place":["Greater London, United\u00a0Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the CONCORD Working Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","published-online":{"date-parts":[[2023,7,24]]},"reference":[{"issue":"10125","key":"e_1_3_2_2_2","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/S0140-6736(17)33326-3","article-title":"Global surveillance of trends in cancer survival 2000\u201014 (CONCORD\u20103): analysis of individual records for 37,513,025 patients diagnosed with one of 18 cancers from 322 population\u2010based registries in 71 countries","volume":"391","author":"Allemani C","year":"2018","unstructured":"Allemani C, Matsuda T, Di Carlo V, Harewood R, Matz M, Nik\u0161i\u0107 M, et\u00a0al. 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