{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T06:33:23Z","timestamp":1783578803600,"version":"3.55.0"},"reference-count":74,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"9","license":[{"start":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T00:00:00Z","timestamp":1749081600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004082","name":"Korean Foundation for Cancer Research","doi-asserted-by":"publisher","award":["CB\u20102022\u2010A\u20101"],"award-info":[{"award-number":["CB\u20102022\u2010A\u20101"]}],"id":[{"id":"10.13039\/501100004082","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004082","name":"Korean Foundation for Cancer Research","doi-asserted-by":"publisher","award":["CB\u20102022\u2010A\u20101"],"award-info":[{"award-number":["CB\u20102022\u2010A\u20101"]}],"id":[{"id":"10.13039\/501100004082","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Commun"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Overweight and obesity are known risk factors for cancer. The aim of this study was to investigate associations of body mass index (BMI) and waist circumference (WC) with incidence of 27 site\u2010specific cancers stratified by sex and menopausal status accounting for non\u2010linearity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p xml:lang=\"en\">We performed a population\u2010based retrospective cohort study using the Korean National Health Insurance Service (KNHIS 2009\u20102020) database. We included 3,986,155 participants (aged \u2265 20 years), and the mean follow\u2010up duration was 9.0 \u00b1 1.6 years. The primary outcome was the incidence of cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">There were positive associations between BMI or WC and incidences of cancers including overall cancer, digestive tract cancer (except for esophageal cancer), hepato\u2010bilio\u2010pancreatic cancer, hematological cancer, sex\u2010specific cancers, brain\/central nervous system (postmenopausal women), thyroid, renal, and bladder cancers. We observed inverse associations for several cancers, including lung and laryngeal cancers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Our findings of differential associations of BMI and WC with incidence of various cancers contribute to the understanding of the relationship between obesity and cancer risk in Asian populations. These results may provide evidence to support the implementation of active surveillance and targeted management strategies for obesity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cac2.70039","type":"journal-article","created":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T02:24:44Z","timestamp":1749176684000},"page":"1075-1089","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Associations of body mass index and waist circumference with incidence of overall and of 27 site\u2010specific cancers: a population\u2010based retrospective cohort study"],"prefix":"10.34133","volume":"45","author":[{"given":"Seonghye","family":"Kim","sequence":"first","affiliation":[{"name":"Sungkyunkwan University School of Medicine","place":["Seoul, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bongseong","family":"Kim","sequence":"additional","affiliation":[{"name":"Soongsil University","place":["Seoul, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyu\u2010won","family":"Jung","sequence":"additional","affiliation":[{"name":"National Cancer Center","place":["Goyang, Republic of Korea"]},{"name":"National Cancer Control Institute","place":["Goyang, Republic of Korea"]},{"name":"National Cancer Center","place":["Goyang, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ga Eun","family":"Nam","sequence":"additional","affiliation":[{"name":"Korea University Guro Hospital","place":["Seoul, Republic of Korea"]},{"name":"Korea University College of Medicine","place":["Seoul, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wonyoung","family":"Jung","sequence":"additional","affiliation":[{"name":"University of Pennsylvania","place":["Philadelphia, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhee","family":"Park","sequence":"additional","affiliation":[{"name":"Kangbuk Samsung Hospital","place":["Seoul, Republic of Korea"]},{"name":"Sungkyunkwan University School of Medicine","place":["Seoul, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung\u2010Do","family":"Han","sequence":"additional","affiliation":[{"name":"Soongsil University","place":["Seoul, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8128-8920","authenticated-orcid":false,"given":"Dong Wook","family":"Shin","sequence":"additional","affiliation":[{"name":"Sungkyunkwan University School of Medicine","place":["Seoul, Republic of Korea"]},{"name":"Sungkyunkwan University","place":["Seoul, Republic of Korea"]},{"name":"Sungkyunkwan University","place":["Seoul, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","published-online":{"date-parts":[[2025,6,5]]},"reference":[{"key":"e_1_3_2_2_2","unstructured":"World Cancer Research Fund . 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