{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T03:35:10Z","timestamp":1773977710021,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,12,22]],"date-time":"2017-12-22T00:00:00Z","timestamp":1513900800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The aim of this study was to investigate the incidence and risk factors of postoperative pneumonia (<jats:styled-content style=\"fixed-case\">POP<\/jats:styled-content>) within 1 year after cancer surgery in patients with the five most common cancers (gastric, colorectal, lung, breast cancer, and hepatocellular carcinoma [<jats:styled-content style=\"fixed-case\">HCC<\/jats:styled-content>]) in South Korea. This was a multicenter and retrospective cohort study performed at five nationwide cancer centers. The number of cancer patients in each center was allocated by the proportion of cancer surgery. Adult patients were randomly selected according to the allocated number, among those who underwent cancer surgery from January to December 2014 within 6\u00a0months after diagnosis of cancer. One\u2010year cumulative incidence of <jats:styled-content style=\"fixed-case\">POP<\/jats:styled-content> was estimated using Kaplan\u2013Meier analysis. An univariable Cox's proportional hazard regression analysis was performed to identify risk factors for <jats:styled-content style=\"fixed-case\">POP<\/jats:styled-content> development. As a multivariable analysis, confounders were adjusted using multiple Cox's <jats:styled-content style=\"fixed-case\">PH<\/jats:styled-content> regression model. Among the total 2000 patients, the numbers of patients with gastric cancer, colorectal cancer, lung cancer, breast cancer, and <jats:styled-content style=\"fixed-case\">HCC<\/jats:styled-content> were 497 (25%), 525 (26%), 277 (14%), 552 (28%), and 149 (7%), respectively. Overall, the 1\u2010year cumulative incidence of <jats:styled-content style=\"fixed-case\">POP<\/jats:styled-content> was 2.0% (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 1.4\u20132.6). The 1\u2010year cumulative incidences in each cancer were as follows: lung 8.0%, gastric 1.8%, colorectal 1.0%, <jats:styled-content style=\"fixed-case\">HCC<\/jats:styled-content> 0.7%, and breast 0.4%. In multivariable analysis, older age, higher Charlson comorbidity index (<jats:styled-content style=\"fixed-case\">CCI<\/jats:styled-content>) score, ulcer disease, history of pneumonia, and smoking were related with <jats:styled-content style=\"fixed-case\">POP<\/jats:styled-content> development. In conclusions, the 1\u2010year cumulative incidence of <jats:styled-content style=\"fixed-case\">POP<\/jats:styled-content> in the five most common cancers was 2%. Older age, higher <jats:styled-content style=\"fixed-case\">CCI<\/jats:styled-content> scores, smoker, ulcer disease, and previous pneumonia history increased the risk of <jats:styled-content style=\"fixed-case\">POP<\/jats:styled-content> development in cancer patients.<\/jats:p>","DOI":"10.1002\/cam4.1259","type":"journal-article","created":{"date-parts":[[2017,12,24]],"date-time":"2017-12-24T07:38:10Z","timestamp":1514101090000},"page":"261-269","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Incidence and risk factors of postoperative pneumonia following cancer surgery in adult patients with selected solid cancer: results of \u201cCancer POP\u201d study"],"prefix":"10.1002","volume":"7","author":[{"given":"Jiwon","family":"Jung","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases Department of Internal Medicine Ulsan University Hospital University of Ulsan College of Medicine  Ulsan Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Song Mi","family":"Moon","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Gachon University Gil Medical Center  Incheon Korea"},{"name":"Division of Infectious Diseases Department of Internal Medicine Armed Forces Capital Hospital  Seongnam Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hee\u2010Chang","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Chonnam National University Medical School  Gwangju Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheol\u2010In","family":"Kang","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Department of Internal Medicine Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae\u2010Bum","family":"Jun","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Department of Internal Medicine Ulsan University Hospital University of Ulsan College of Medicine  Ulsan Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong Kyun","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Gachon University Gil Medical Center  Incheon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung\u2010Ji","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Chonnam National University Medical School  Gwangju Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo\u2010Jeong","family":"Seo","sequence":"additional","affiliation":[{"name":"Outcomes Research\/Real World Data Corporate Affairs &amp; Health and Value Pfizer Pharmaceuticals Korea Ltd.  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