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Long noncoding <jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>s (lnc<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>s), which play essential roles in the tumorigenesis and metastasis of <jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content> and interplay with micro<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>s (mi<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>s) and <jats:styled-content style=\"fixed-case\">mRNA<\/jats:styled-content>s, are hopefully considered to be efficient biomarkers to detect deterioration during the progression of <jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content> to improve the prognosis. Bioinformatics analysis was fully applied to predict the vital lnc<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>s and the associated mi<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>s and <jats:styled-content style=\"fixed-case\">mRNA<\/jats:styled-content>s, which eventually constructed the competing endogenous <jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content> (ce<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>) network to explain the <jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content> expression patterns in the progression of <jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content>. Further statistical analysis emphasized the importance of these key genes, which were statistically significantly related to one or few clinical features from the ce<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content> network. The results showed the lnc<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>s <jats:styled-content style=\"fixed-case\">MGC<\/jats:styled-content>12926 and <jats:styled-content style=\"fixed-case\">LINC<\/jats:styled-content>00937 were verified to be strongly connected with the prognosis of <jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content> patients.<\/jats:p>","DOI":"10.1002\/cam4.1315","type":"journal-article","created":{"date-parts":[[2018,3,9]],"date-time":"2018-03-09T15:32:54Z","timestamp":1520609574000},"page":"1019-1029","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Integrative analysis of competing endogenous <scp>RNA<\/scp> network focusing on long noncoding <scp>RNA<\/scp> associated with progression of cutaneous melanoma"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5147-2644","authenticated-orcid":false,"given":"Siyi","family":"Xu","sequence":"first","affiliation":[{"name":"Key Laboratory of Environmental Medicine Engineering Ministry of Education School of Public Health Southeast University  Nanjing Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Sui","sequence":"additional","affiliation":[{"name":"Key Laboratory of Environmental Medicine Engineering Ministry of Education School of Public Health Southeast University  Nanjing Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Yang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Environmental Medicine Engineering Ministry of Education School of Public Health Southeast University  Nanjing Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufeng","family":"Liu","sequence":"additional","affiliation":[{"name":"TCM of Jiangsu Provincial Hospital  Nanjing Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Dermatology Chinese Academy of Medical Sciences and Peking Union Medical College Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs  Nanjing Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geyu","family":"Liang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Environmental Medicine Engineering Ministry of Education School of Public Health Southeast University  Nanjing Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,3,9]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2014.07.022"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.3892\/ijo.2014.2691"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1188\/15.CJON.430-432"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.17446611"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S98203"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.3892\/ijo.2016.3377"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/7038579"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2016.12.006"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.132159.111"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.14763"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.140061.112"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2016.04.010"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i41.11680"},{"key":"e_1_2_5_15_1","first-page":"1177","article-title":"A meta\u2010analysis of the literature for whole\u2010body FDG PET detection of recurrent colorectal cancer","volume":"41","author":"Huebner R. 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