{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T18:35:35Z","timestamp":1791311735934,"version":"4.3.1"},"reference-count":46,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,4,13]],"date-time":"2018-04-13T00:00:00Z","timestamp":1523577600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2018,7]]},"abstract":"Abstract<\/jats:title>Evaluating population\u2010based data of hematologic malignancies (HM<\/jats:styled-content>s) in older adults provides prognostic information for this growing demographic. Incidence rates and one\u2010 and five\u2010year relative survival rates were examined for specific HM<\/jats:styled-content>s among adults ages \u226575\u00a0years using data from the Surveillance, Epidemiology and End Results (SEER<\/jats:styled-content>) Program. Hematologic malignancy cases (Hodgkin lymphoma (HL<\/jats:styled-content>), non\u2010Hodgkin lymphoma (NHL<\/jats:styled-content>), multiple myeloma (MM<\/jats:styled-content>), acute lymphocytic leukemia (ALL<\/jats:styled-content>), chronic lymphocytic leukemia (CLL<\/jats:styled-content>), acute myeloid leukemia (AML<\/jats:styled-content>), and chronic myeloid leukemia (CML<\/jats:styled-content>)) were reported to one of 18 SEER<\/jats:styled-content> registries. Recent average annual (2010\u20132014) incidence rates and incidence trends from 1973 to 2014 were examined for cases ages \u226575\u00a0years. One\u2010 and five\u2010year relative cancer survival rates were examined for adults ages \u226575\u00a0years diagnosed 2007\u20132013, with follow\u2010up into 2014. From 1973 to 2014, incidence rates increased for NHL<\/jats:styled-content>, MM<\/jats:styled-content>, and AML<\/jats:styled-content>, decreased for HL<\/jats:styled-content>, and remained relatively stable for ALL<\/jats:styled-content>, CLL<\/jats:styled-content>, and CML<\/jats:styled-content> among adults ages \u226575\u00a0years. The highest one\u2010 and five\u2010year relative survival rates were observed among adults with CLL<\/jats:styled-content> ages 75\u201384\u00a0years (1\u00a0year: 91.8% (95% CI<\/jats:styled-content>\u00a0=\u00a091.8\u201390.8)) and 5\u00a0years: 76.5% (95% CI<\/jats:styled-content>\u00a0=\u00a074.2\u201378.6)). The lowest one\u2010 and five\u2010year survival rates were observed among adults with AML<\/jats:styled-content> ages 75\u201384 (1\u00a0year: 18.2% (95% CI<\/jats:styled-content>\u00a0=\u00a074.2\u201378.6) and 5\u00a0years: 2.7% (95% CI<\/jats:styled-content>\u00a0=\u00a02.0\u20133.6)). Survival for older adults ages \u226575\u00a0years with HM<\/jats:styled-content>s is poor, particularly for acute leukemia. Understanding the heterogeneity in HM<\/jats:styled-content> outcomes among older patients may help clinicians better address the hematological cancer burden and mortality in the aging population.<\/jats:p>","DOI":"10.1002\/cam4.1461","type":"journal-article","created":{"date-parts":[[2018,4,14]],"date-time":"2018-04-14T02:29:16Z","timestamp":1523672956000},"page":"3425-3433","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":70,"title":["Incidence and survival of hematological cancers among adults ages \u226575\u00a0years"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2484-5887","authenticated-orcid":false,"given":"Jessica L.","family":"Krok\u2010Schoen","sequence":"first","affiliation":[{"name":"Division of Medical Dietetics and Health Sciences School of Health and Rehabilitation Sciences College of Medicine The Ohio State University Columbus Ohio"},{"name":"Comprehensive Cancer Center The Ohio State University Columbus Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James L.","family":"Fisher","sequence":"additional","affiliation":[{"name":"Arthur G. James Cancer Hospital and Richard J. Solove Research Institute Columbus Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie A.","family":"Stephens","sequence":"additional","affiliation":[{"name":"Center for Biostatistics The Ohio State University Columbus Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Mims","sequence":"additional","affiliation":[{"name":"Arthur G. James Cancer Hospital and Richard J. Solove Research Institute Columbus Ohio"},{"name":"Division of Hematology Department of Internal Medicine College of Medicine The Ohio State University Columbus Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabarish","family":"Ayyappan","sequence":"additional","affiliation":[{"name":"Arthur G. James Cancer Hospital and Richard J. Solove Research Institute Columbus Ohio"},{"name":"Division of Hematology Department of Internal Medicine College of Medicine The Ohio State University Columbus Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer A.","family":"Woyach","sequence":"additional","affiliation":[{"name":"Arthur G. James Cancer Hospital and Richard J. Solove Research Institute Columbus Ohio"},{"name":"Division of Hematology Department of Internal Medicine College of Medicine The Ohio State University Columbus Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5875-3214","authenticated-orcid":false,"given":"Ashley E.","family":"Rosko","sequence":"additional","affiliation":[{"name":"Arthur G. James Cancer Hospital and Richard J. 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