{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T16:42:21Z","timestamp":1775666541110,"version":"3.50.1"},"reference-count":42,"publisher":"Wiley","issue":"21","license":[{"start":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T00:00:00Z","timestamp":1599004800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2016A030313197"],"award-info":[{"award-number":["2016A030313197"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>This study aimed to assess the health\u2010related quality of life (HRQOL) of Chinese patients with different stages of multiple myeloma (MM) who received various treatments and identify the factors associated with a lower quality of life in China.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional, anonymous questionnaire was distributed to adults with MM. The measures of quality of life included the European Organization for Research and Treatment of Cancer (EORTC) quality of life questionnaire (QLQ)\u2010C30, QLQ\u2010myeloma\u2010specific module 20 (MY20), and EuroQoL EQ\u20105D. The data, including patient factors, difficulties experienced during the diagnosis and treatment processes, psychosocial factors and disease\u2010 or treatment\u2010related effects, were collected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Four hundred and thirty patients with MM were recruited from all 27 provinces of China, and their average age was 55.7\u00a0years. Many variables were significantly associated with the HRQOL of the patients with MM. In the multivariate analyses, performance status, psychosocial factors, disease phase, and an early diagnosis were significantly associated with the HRQOL. In the subgroup analysis, the HRQOL of the patients who underwent autologous stem cell transplantation (ASCT) was significantly higher than that of the non\u2010ASCT patients. Treatment\u2010related toxicities had a significant impact on the quality of life of the patients with MM, and 91.5% of the patients intended to stop the maintenance treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The quality of life of patients with MM in China is affected by patient factors, difficulties experienced during the diagnosis and treatment processes, psychosocial factors, and disease\u2010 or treatment\u2010related effects. Efforts should be exerted to improve the overall quality of life of these patients in China.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.3391","type":"journal-article","created":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T20:07:59Z","timestamp":1599077279000},"page":"7896-7913","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Health\u2010related quality of life of patients with multiple myeloma: A real\u2010world study in China"],"prefix":"10.1002","volume":"9","author":[{"given":"Xiaozhe","family":"Li","sequence":"first","affiliation":[{"name":"Department of Haematology The First Affiliated Hospital of Sun Yat\u2010sen University Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junru","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Haematology The First Affiliated Hospital of Sun Yat\u2010sen University Guangzhou 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