{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T22:14:04Z","timestamp":1792707244809,"version":"4.5.0"},"reference-count":46,"publisher":"Wiley","issue":"16","license":[{"start":{"date-parts":[[2021,7,2]],"date-time":"2021-07-02T00:00:00Z","timestamp":1625184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30 CA008748"],"award-info":[{"award-number":["P30 CA008748"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Yoga is a meditative movement therapy focused on mind\u2010body awareness. The impact of yoga on health\u2010related quality of life (HRQOL) outcomes in patients with chemotherapy\u2010induced peripheral neuropathy (CIPN) is unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a pilot randomized wait\u2010list controlled trial of 8\u00a0weeks of yoga (n\u00a0=\u00a021) versus wait\u2010list control (n\u00a0=\u00a020) for CIPN in 41 breast and gynecological cancer survivors with persistent moderate to severe CIPN. HRQOL endpoints were Hospital Anxiety and Depression Scale (HADS), Brief Fatigue Inventory (BFI), and Insomnia Severity Index (ISI). The Treatment Expectancy Scale (TES) was administered at baseline. We estimated mean changes and 95% confidence intervals (CIs) from baseline to weeks 8 and 12 and compared arms using constrained linear mixed models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At week 8, HADS anxiety scores decreased \u22121.61 (\u22122.75, \u22120.46) in the yoga arm and \u22120.32 (\u22121.38, 0.75) points in the wait\u2010list control arm (<jats:italic>p\u00a0<\/jats:italic>=\u00a00.099). At week 12, HADS anxiety scores decreased \u22121.42 (\u22122.57, \u22120.28) in yoga compared to an increase of 0.46 (\u22120.60, 1.53) in wait\u2010list control (<jats:italic>p\u00a0<\/jats:italic>=\u00a00.017). There were no significant differences in HADS depression, BFI, or ISI scores between yoga and wait\u2010list control. Baseline TES was significantly higher in yoga than in wait\u2010list control (14.9 vs. 12.7, <jats:italic>p\u00a0<\/jats:italic>=\u00a00.019). TES was not associated with HADS anxiety reduction and HADS anxiety reduction was not associated with CIPN pain reduction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Yoga may reduce anxiety in patients with CIPN. Future studies are needed to confirm these findings.<\/jats:p><jats:p><jats:bold>Clinical Trial Registration Number:<\/jats:bold> ClinicalTrials.gov Identifier: NCT03292328.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.4098","type":"journal-article","created":{"date-parts":[[2021,7,2]],"date-time":"2021-07-02T10:45:14Z","timestamp":1625222714000},"page":"5456-5465","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Yoga for cancer survivors with chemotherapy\u2010induced peripheral neuropathy: Health\u2010related quality of life outcomes"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4263-7272","authenticated-orcid":false,"given":"W. 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